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The AAN provides the highest quality scientific education to the neurology community worldwide. Read the AAN's journals, discover CME publications, and browse reports on breaking news, issues, and trends in neurology.

AAN Family of Publications

Neurology ®

The AAN’s flagship journal includes the latest peer-reviewed original clinical research articles, AAN position papers and clinical guidelines, editorials, and reviews that enhance the field of neurology and influence patient care. The journal’s impact factor is 10.1.

Earn CME credit by reading two articles selected weekly by the editors and taking the exams online.

Neurology ® Clinical Practice

Read peer-reviewed articles and commentaries on clinical topics, practice management, health policy issues, ethical issues, and updates on diseases and disorders. Articles are available in PubMed Central one year after publication. The journal’s impact factor is 2.2.

Neurology ® Neuroimmunology & Neuroinflammation

An online-only, open-access journal with peer-reviewed reports of research affecting the full range of neurological diseases. Articles, editorials, and reviews aim to facilitate basic and translational research, along with enhancing patient care. The journal’s impact factor is 8.8.

Neurology ® Genetics

An online-only, open-access journal with peer-reviewed reports in neurogenetics that elucidate the role of genetic and epigenetic variations in diseases and biological traits of the central and peripheral nervous systems. The journal’s impact factor is 4.1.

Neurology ® Education  

An online-only, open access journal in the field of neurological and neuroscience education research. Original research articles, reviews, and editorials on evidence-based teaching methods and curriculum innovations provide the academic community with a forum to exchange ideas that enhance teaching and training.

Continuum: Lifelong Learning in Neurology ®

An in-depth clinically oriented review journal for neurology professionals. Written by authors who are experts in their field, each bimonthly issue contains up-to-date knowledge around a single topic area in neurology with continuing medical education (CME) available.

Continuum ® Audio features conversations with Continuum ® authors that supplement each journal article and provide an opportunity for additional CME.

Neurology Today ®

The AAN's official news source, reporting on breaking news, issues, and trends in neurology. The publication provides an inside track to advances from the AAN, Neurology ® , and other peer-reviewed neurology and medical journals. Published in print twice a month.

Brain & Life ®

A free magazine and website for patients, caregivers, and anyone interested in brain health. Articles connect readers with stories of people living with brain disease, the latest research, and perspectives on neurological disorders and brain health not found anywhere else. A print subscription (six issues a year) is available to anyone residing in the United States.

Brain & Life ® en Español

A free magazine for Spanish-speaking readers, published quarterly and is mailed to interested readers in the United States with all content available online.

Brain & Life and Brain & Life en Español print issues are available in bulk to AAN members in the US to share with your patients. Email [email protected] to learn more.

Explore the publications' podcasts, including the Brain & Life ®  Podcast, Neurology ® Podcast, and Neurology Minute ®

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Collection  10 March 2022

Top 100 in Neuroscience

This collection highlights our most downloaded* neuroscience papers published in 2021. Featuring authors from around the world, these papers showcase valuable research from an international community.

*Data obtained from SN Inights, which is based on Digital Science's Dimensions.

Musical components important for the Mozart K448 effect in epilepsy

• Robert J. Quon
• Michael A. Casey
• Barbara C. Jobst

Brain structure changes associated with sexual orientation

• Mikhail Votinov
• Katharina S. Goerlich

Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain

• Fabien Dachet
• James B. Brown
• Jeffrey A. Loeb

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

• Lisa Mosconi
• Valentina Berti
• Roberta Diaz Brinton

Multimodal deep learning models for early detection of Alzheimer’s disease stage

• Janani Venugopalan
• May D. Wang

Brain tumor segmentation based on deep learning and an attention mechanism using MRI multi-modalities brain images

• Ramin Ranjbarzadeh
• Abbas Bagherian Kasgari
• Malika Bendechache

Splitting sleep between the night and a daytime nap reduces homeostatic sleep pressure and enhances long-term memory

• James N. Cousins
• Ruth L. F. Leong
• Michael W. L. Chee

Listening to speech with a guinea pig-to-human brain-to-brain interface

• Claus-Peter Richter
• Petrina La Faire
• Alan G. Micco

Benefit of human moderate running boosting mood and executive function coinciding with bilateral prefrontal activation

• Chorphaka Damrongthai
• Ryuta Kuwamizu
• Hideaki Soya

Enhanced activations in syntax-related regions for multilinguals while acquiring a new language

• Keita Umejima
• Suzanne Flynn
• Kuniyoshi L. Sakai

Brain-inspired spiking neural networks for decoding and understanding muscle activity and kinematics from electroencephalography signals during hand movements

• Kaushalya Kumarasinghe
• Nikola Kasabov
• Denise Taylor

Longitudinal effects of meditation on brain resting-state functional connectivity

• Zongpai Zhang
• Wen-Ming Luh
• Weiying Dai

Evidence of a new hidden neural network into deep fasciae

• Caterina Fede
• Lucia Petrelli
• Carla Stecco

Cross-sex hormone treatment and own-body perception: behavioral and brain connectivity profiles

• Behzad S. Khorashad
• Amirhossein Manzouri
• Ivanka Savic

A directional 3D neurite outgrowth model for studying motor axon biology and disease

• Xandor M. Spijkers
• Svetlana Pasteuning-Vuhman
• R. Jeroen Pasterkamp

The role of dorsolateral and ventromedial prefrontal cortex in the processing of emotional dimensions

• Vahid Nejati
• Reyhaneh Majdi
• Michael A. Nitsche

How neurons exploit fractal geometry to optimize their network connectivity

• Julian H. Smith
• Conor Rowland
• R. P. Taylor

Defining early changes in Alzheimer’s disease from RNA sequencing of brain regions differentially affected by pathology

• Boris Guennewig
• Greg T. Sutherland

Narcissistic personality traits and prefrontal brain structure

• Igor Nenadić
• Carsten Lorenz
• Christian Gaser

EEG-based diagnostics of the auditory system using cochlear implant electrodes as sensors

• Christopher J. Long
• Tom Francart

Investigating real-life emotions in romantic couples: a mobile EEG study

• Julian Packheiser
• Gesa Berretz
• Sebastian Ocklenburg

Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice

• Kauê Machado Costa
• Daniela Schenkel
• Jochen Roeper

Functional network connectivity during Jazz improvisation

• Victor M. Vergara
• Martin Norgaard
• Vince D. Calhoun

Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice

• Jeon-Kyung Kim
• Sang-Kap Han
• Dong-Hyun Kim

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

• Bradley R. Groveman
• Natalia C. Ferreira
• Cathryn L. Haigh

Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model

• YoungSoo Kim

Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning

• Mona Nasseri
• Tal Pal Attia
• Benjamin H. Brinkmann

Post-traumatic seizures and antiepileptic therapy as predictors of the functional outcome in patients with traumatic brain injury

• Valeria Pingue
• Chiara Mele
• Antonio Nardone

Human α-synuclein overexpression in a mouse model of Parkinson’s disease leads to vascular pathology, blood brain barrier leakage and pericyte activation

• Osama Elabi
• Abderahim Gaceb
• Gesine Paul

Neuropsychiatric profiles and conversion to dementia in mild cognitive impairment, a latent class analysis

• Natalia Roberto
• Maria J. Portella
• Sergi Valero

Comparative neuroanatomy of the lumbosacral spinal cord of the rat, cat, pig, monkey, and human

• Amirali Toossi
• Bradley Bergin
• Vivian K. Mushahwar

A personalized and evolutionary algorithm for interpretable EEG epilepsy seizure prediction

• Mauro. F. Pinto
• Adriana Leal
• César A. Teixeira

The effects of positive or negative self-talk on the alteration of brain functional connectivity by performing cognitive tasks

• Junhyung Kim
• Joon Hee Kwon
• Jae-Jin Kim

Deep learning-Based 3D inpainting of brain MR images

• Seung Kwan Kang
• Seong A. Shin
• Jae Sung Lee

Both high fat and high carbohydrate diets impair vagus nerve signaling of satiety

• Hailley Loper
• Monique Leinen
• Matthew A. Schiefer

PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons

• Sarah J. Brown
• Ibrahim Boussaad
• Oliver Bandmann

Altered spontaneous activity in the frontal gyrus in dry eye: a resting-state functional MRI study

Online and offline effects of transcranial alternating current stimulation of the primary motor cortex

• Ivan Pozdniakov
• Alicia Nunez Vorobiova
• Matteo Feurra

Cell type-specific changes in transcriptomic profiles of endothelial cells, iPSC-derived neurons and astrocytes cultured on microfluidic chips

• H. H. T. Middelkamp
• A. H. A. Verboven
• A. D. van der Meer

Brain MRI in SARS-CoV-2 pneumonia patients with newly developed neurological manifestations suggestive of brain involvement

• Batil Alonazi
• Ahmed M. Farghaly
• Mustafa Z. Mahmoud

Diazepam causes sedative rather than anxiolytic effects in C57BL/6J mice

• Marina Pádua-Reis
• Diana Aline Nôga
• Martina Blunder

Photons detected in the active nerve by photographic technique

• Andrea Zangari
• Davide Micheli
• Maria Emiliana Caristo

Cannabidiol induces autophagy via ERK1/2 activation in neural cells

• Talita A. M. Vrechi
• Anderson H. F. F. Leão
• Gustavo J. S. Pereira

Deep learning-based pupil model predicts time and spectral dependent light responses

• Babak Zandi
• Tran Quoc Khanh

ATP signaling in the integrative neural center of Aplysia californica

• János Györi
• Andrea B. Kohn
• Leonid L. Moroz

EEG signals respond differently to idea generation, idea evolution and evaluation in a loosely controlled creativity experiment

Cognitive and MRI trajectories for prediction of Alzheimer’s disease

• Samaneh A. Mofrad
• Astri J. Lundervold
• Alexander S. Lundervold

Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

• Angela Duong
• Alesya Evstratova
• Ana C. Andreazza

Astrocytic expression of the Alzheimer’s disease risk allele, ApoEε4, potentiates neuronal tau pathology in multiple preclinical models

• Angela Marie Jablonski
• Bhavya Voleti

Effects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy

• Samantha T. Reyes
• Robert M. J. Deacon
• Frederick T. Chin

Magnetic domains oscillation in the brain with neurodegenerative disease

• Gunther Kletetschka
• Robert Bazala
• Eva Svecova

Right frontal anxiolytic-sensitive EEG ‘theta’ rhythm in the stop-signal task is a theory-based anxiety disorder biomarker

• Shabah M. Shadli
• Lynne C. Ando
• Neil McNaughton

Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation

• Debora Giunti
• Chiara Marini
• Antonio Uccelli

Position sensitive measurement of trace lithium in the brain with NIK (neutron-induced coincidence method) in suicide

• J. Schoepfer
• R. Gernhäuser

Major oscillations in spontaneous home-cage activity in C57BL/6 mice housed under constant conditions

• Karin Pernold
• Eric Rullman
• Brun Ulfhake

Involvement of the dopaminergic system in the reward-related behavior of pregabalin

• Yusuf S. Althobaiti
• Farooq M. Almutairi
• Zahoor A. Shah

A high-density electroencephalography study reveals abnormal sleep homeostasis in patients with rapid eye movement sleep behavior disorder

• Amandine Valomon
• Brady A. Riedner
• Melanie Boly

MEG signatures of long-term effects of agreement and disagreement with the majority

• V. Klucharev
• A. Shestakova

Stroke prediction in patients presenting with isolated dizziness in the emergency department

• June-sung Kim
• Hong Jun Bae
• Won Young Kim

Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption

• Amy C. Reichelt
• Claire A. Lemieux
• Lisa M. Saksida

Recording site placement on planar silicon-based probes affects signal quality in acute neuronal recordings

• Richárd Fiáth
• Domokos Meszéna
• István Ulbert

Amplification of potential thermogenetic mechanisms in cetacean brains compared to artiodactyl brains

• Paul R. Manger
• Nina Patzke

Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth

• Marion I. van den Heuvel
• Jasmine L. Hect
• Moriah E. Thomason

An anomaly detection approach to identify chronic brain infarcts on MRI

• Kees M. van Hespen
• Jaco J. M. Zwanenburg
• Hugo J. Kuijf

The neurodynamic treatment induces biological changes in sensory and motor neurons in vitro

• Giacomo Carta
• Giovanna Gambarotta
• Federica Fregnan

Optimal flickering light stimulation for entraining gamma waves in the human brain

• Kanghee Lee
• Yeseung Park
• Ki Woong Kim

Two-photon GCaMP6f imaging of infrared neural stimulation evoked calcium signals in mouse cortical neurons in vivo

• Attila Kaszas
• Gergely Szalay
• David Moreau

The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression

• Maa O. Quartey
• Jennifer N. K. Nyarko
• Darrell D. Mousseau

Drinking coffee enhances neurocognitive function by reorganizing brain functional connectivity

• Sung Hoon Kang
• Jung Bin Kim

The impact of multisensory integration and perceptual load in virtual reality settings on performance, workload and presence

• Matteo Marucci
• Gianluca Di Flumeri
• Pietro Aricò

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

• Jeremy S. Lum
• Mikayla L. Brown
• Justin J. Yerbury

Underlying neurological mechanisms associated with symptomatic convergence insufficiency

• Tara L. Alvarez
• Mitchell Scheiman
• Bharat B. Biswal

Paternal exposure to a common pharmaceutical (Ritalin) has transgenerational effects on the behaviour of Trinidadian guppies

• Alex R. De Serrano
• Kimberly A. Hughes
• F. Helen Rodd

Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT 2A receptor activation

• April Contreras
• Matthew Khumnark
• Dustin J. Hines

Focused ultrasound mediated blood–brain barrier opening is safe and feasible in a murine pontine glioma model

• Zachary K. Englander
• Hong-Jian Wei
• Cheng-Chia Wu

Basmisanil, a highly selective GABA A -α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man

• Joerg F. Hipp
• Frederic Knoflach
• Maria-Clemencia Hernandez

Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model

• Shinwoo Kang
• Keun-A Chang

The gut microbiome is associated with brain structure and function in schizophrenia

Static and dynamic functional connectivity supports the configuration of brain networks associated with creative cognition

• Abhishek Uday Patil
• Sejal Ghate
• Chih-Mao Huang

Digital signatures for early traumatic brain injury outcome prediction in the intensive care unit

• Anil K. Palepu
• Aditya Murali
• Robert D. Stevens

LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1

• Ramona M. Rodriguiz
• Vineet Nadkarni
• William C. Wetsel

Modified wavelet analysis of ECoG-pattern as promising tool for detection of the blood–brain barrier leakage

• Anastasiya Runnova
• Maksim Zhuravlev
• Jurgen Kurths

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization

• Hiromu Monai
• Shinnosuke Koketsu
• Hajime Hirase

An atlas for human brain myelin content throughout the adult life span

• Adam V. Dvorak
• Taylor Swift-LaPointe
• Shannon H. Kolind

Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex

• Carlos A. Sánchez-León
• Isabel Cordones
• Javier Márquez-Ruiz

Human brain dynamics in active spatial navigation

• Tien-Thong Nguyen Do
• Chin-Teng Lin
• Klaus Gramann

Reading without phonology: ERP evidence from skilled deaf readers of Spanish

• Brendan Costello
• Sendy Caffarra
• Manuel Carreiras

Alterations in reward network functional connectivity are associated with increased food addiction in obese individuals

• Soumya Ravichandran
• Ravi R. Bhatt
• Arpana Gupta

Disease progression modelling from preclinical Alzheimer’s disease (AD) to AD dementia

• Soo Hyun Cho
• Sookyoung Woo
• Sang Won Seo

The structure dilemma in biological and artificial neural networks

• Thomas Pircher
• Bianca Pircher
• Andreas Feigenspan

Voluntary intake of psychoactive substances is regulated by the dopamine receptor Dop1R1 in Drosophila

• Shun Hiramatsu
• Toshiharu Ichinose

The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder

• Cristan A. Farmer
• Audrey E. Thurm
• Joan C. Han

Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease

• Victoria Monge-Fuentes
• Andréia Biolchi Mayer
• Márcia Renata Mortari

NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury

• Frances Corrigan
• Ibolja Cernak
• Robert Vink

Nicotine suppresses Parkinson’s disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels

• Angel Carvajal-Oliveros
• Carmen Domínguez-Baleón
• Enrique Reynaud

Free-water diffusion tensor imaging improves the accuracy and sensitivity of white matter analysis in Alzheimer’s disease

• Maurizio Bergamino
• Ryan R. Walsh
• Ashley M. Stokes

A functional spiking neuronal network for tactile sensing pathway to process edge orientation

• Adel Parvizi-Fard
• Mahmood Amiri
• Nitish V. Thakor

The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells

• Kim Le Cann
• Alec Foerster
• Angelika Lampert

Hippocampus-retrosplenial cortex interaction is increased during phasic REM and contributes to memory consolidation

• Daniel Gomes de Almeida-Filho
• Bruna Del Vechio Koike
• Claudio Marcos Queiroz

Machine learning-based classification of mitochondrial morphology in primary neurons and brain

• Garrett M. Fogo
• Anthony R. Anzell
• Thomas H. Sanderson

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