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122 The Best Genetics Research Topics For Projects

The study of genetics takes place across different levels of the education system in academic facilities all around the world. It is an academic discipline that seeks to explain the mechanism of heredity and genes in living organisms. First discovered back in the 1850s, the study of genetics has come a pretty long way, and it plays such an immense role in our everyday lives. Therefore, when you are assigned a genetics research paper, you should pick a topic that is not only interesting to you but one that you understand well.

Choosing Research Topics in Genetics

Even for the most knowledgeable person in the room, choosing a genetics topic for research papers can be, at times, a hectic experience. So we put together a list of some of the most exciting top in genetics to make the endeavor easier for you. However, note, while all the topics we’ve listed below will enable you to write a unique genetic project, remember what you choose can make or break your paper. So again, select a topic that you are both interested and knowledgeable on, and that has plenty of research materials to use. Without further ado, check out the topics below.

Interesting Genetics Topics for your Next Research Paper

Genes and DNA: write a beginners’ guide to genetics and its applications
Factors that contribute or/and cause genetic mutations
Genetics and obesity, what do you need to know?
Describe RNA information
Is there a possibility of the genetic code being confidential?
Are there any living cells present in the gene?
Cancer and genetics
Describe the role of genetics in the fight against Alzheimer’s disease
What is the gene
Is there a link between genetics and Parkinson’s disease? Explain your answer.
Replacement of genes and artificial chromosomes
Explain genetic grounds for obesity
Development and disease; how can genetics dissect the developing process
Analyzing gene expression – RNA
Gene interaction; eye development
Advances and developments in nanotechnology to enable therapeutic methods for the treatment of HIV and AIDS.
Isolating and identifying the cancer treatment activity of special organic metal compounds.
Analyzing the characteristics in certain human genes that can withstand heavy metals.
A detailed analysis of genotypes that is both sensitive and able to endure heavy metals.
Isolating special growth-inducing bacteria that can assist crops during heavy metal damage and identifying lipid directing molecules for escalating heavy metal endurance in plants.

Hot and Controversial Topics in Genetics

Is there a link between genetics and homosexuality? Explain your answer
Is it ethical and morally upright to grow human organs
Can DNA changes beat aging
The history and development of human cloning science
How addictive substances alter our genes
Are genetically modified foods safe for human and animal consumption?
Is depression a genetically based condition?
Genetic diagnosis of the fetus
Genetic analysis of the DNA structure
What impact does cloning have on future generations?
What is the link between genetics and autism?
Can artificial insemination have any sort of genetic impact on a person?
The advancements in genetic research and the bioethics that come with them.
Is human organ farming a possibility today?
Can genetics allow us to design and build a human to our specifications?
Is it ethical to try and tamper with human genetics in any way?

Molecular Genetics Topics

Molecular techniques: How to analyze DNA(including genomes), RNA as well as proteins
Stem cells describe their potential and shortcomings
Describe molecular and genome evolution
Describe DNA as the agent of heredity
Explain the power of targeted mutagenesis
Bacteria as a genetic system
Explain how genetic factors increase cancer susceptibility
Outline and describe recent advances in molecular cancer genetics
Does our DNA sequencing have space for more?
Terminal illness and DNA.
Does our DNA determine our body structure?
What more can we possibly discover about DNA?

Genetic Engineering Topics

Define gene editing, and outline key gene-editing technologies, explaining their impact on genetic engineering
The essential role the human microbiome plays in preventing diseases
The principles of genetic engineering
Project on different types of cloning
What is whole genome sequencing
Explain existing studies on DNA-modified organisms
How cloning can impact medicine
Does our genetics hold the key to disease prevention?
Can our genetics make us resistant to certain bacteria and viruses?
Why our genetics plays a role in chronic degenerative diseases.
Is it possible to create an organism in a controlled environment with genetic engineering?
Would cloning lead to new advancements in genetic research?
Is there a possibility to enhance human DNA?
Why do we share DNA with so many other animals on the planet?
Is our DNA still evolving or have reached our biological limit?
Can human DNA be manipulated on a molecular or atomic level?
Do we know everything there is to know about our DNA, or is there more?

Controversial Human Genetic Topics

Who owns the rights to the human genome
Is it legal for parents to order genetically perfect children
is genetic testing necessary
What is your stand on artificial insemination vs. ordinary pregnancy
Do biotech companies have the right to patent human genes
Define the scope of the accuracy of genetic testing
Perks of human genetic engineering
Write about gene replacement and its relationship to artificial chromosomes.
Analyzing DNA and cloning
DNA isolation and nanotechnology methods to achieve it.
Genotyping of African citizens.
Greatly mutating Y-STRs and the isolated study of their genetic variation.
The analytical finding of indels and their genetic diversity.

DNA Research Paper Topics

The role and research of DNA are so impactful today that it has a significant effect on our daily lives today. From health care to medication and ethics, over the last few decades, our knowledge of DNA has experienced a lot of growth. A lot has been discovered from the research of DNA and genetics.

Therefore, writing a good research paper on DNA is quite the task today. Choosing the right topic can make things a lot easier and interesting for writing your paper. Also, make sure that you have reliable resources before you begin with your paper.

Can we possibly identify and extract dinosaur DNA?
Is the possibility of cloning just around the corner?
Is there a connection between the way we behave and our genetic sequence?
DNA research and the environment we live in.
Does our DNA sequencing have something to do with our allergies?
The connection between hereditary diseases and our DNA.
The new perspectives and complications that DNA can give us.
Is DNA the reason all don’t have similar looks?
How complex human DNA is.
Is there any sort of connection between our DNA and cancer susceptibility and resistance?
What components of our DNA affect our decision-making and personality?
Is it possible to create DNA from scratch under the right conditions?
Why is carbon such a big factor in DNA composition?
Why is RNA something to consider in viral research and its impact on human DNA?
Can we detect defects in a person’s DNA before they are born?

Genetics Topics For Presentation

The subject of genetics can be quite broad and complex. However, choosing a topic that you are familiar with and is unique can be beneficial to your presentation. Genetics plays an important part in biology and has an effect on everyone, from our personal lives to our professional careers.

Below are some topics you can use to set up a great genetics presentation. It helps to pick a topic that you find engaging and have a good understanding of. This helps by making your presentation clear and concise.

Can we create an artificial gene that’s made up of synthetic chromosomes?
Is cloning the next step in genetic research and engineering?
The complexity and significance of genetic mutation.
The unlimited potential and advantages of human genetics.
What can the analysis of an individual’s DNA tell us about their genetics?
Is it necessary to conduct any form of genetic testing?
Is it ethical to possibly own a patent to patent genes?
How accurate are the results of a genetics test?
Can hereditary conditions be isolated and eliminated with genetic research?
Can genetically modified food have an impact on our genetics?
Can genetics have a role to play in an individual’s sexuality?
The advantages of further genetic research.
The pros and cons of genetic engineering.
The genetic impact of terminal and neurological diseases.

Biotechnology Topics For Research Papers

As we all know, the combination of biology and technology is a great subject. Biotechnology still offers many opportunities for eager minds to make innovations. Biotechnology has a significant role in the development of modern technology.

Below you can find some interesting topics to use in your next biotechnology research paper. Make sure that your sources are reliable and engage both you and the reader.

Settlements that promote sustainable energy technology maintenance.
Producing ethanol through molasses emission treatment.
Evapotranspiration and its different processes.
Circular biotechnology and its widespread framework.
Understanding the genes responsible for flora response to harsh conditions.
Molecule signaling in plants responding to dehydration and increased sodium.
The genetic improvement of plant capabilities in major crop yielding.
Pharmacogenomics on cancer treatment medication.
Pharmacogenomics on hypertension treating medication.
The uses of nanotechnology in genotyping.
How we can quickly detect and identify food-connected pathogens using molecular-based technology.
The impact of processing technology both new and traditional on bacteria cultures linked to Aspalathus linearis.
A detailed analysis of adequate and renewable sorghum sources for bioethanol manufacturing in South Africa.
A detailed analysis of cancer treatment agents represented as special quinone compounds.
Understanding the targeted administering of embelin to cancerous cells.

Tips for Writing an Interesting Genetics Research Paper

All the genetics research topics above are excellent, and if utilized well, could help you come up with a killer research paper. However, a good genetics research paper goes beyond the topic. Therefore, besides choosing a topic, you are most interested in, and one with sufficient research materials ensure you

Fully Understand the Research Paper Format

You may write on the most interesting genetics topics and have a well-thought-out set of ideas, but if your work is not arranged in an engaging and readable manner, your professor is likely to dismiss it, without looking at what you’ve written. That is the last thing you need as a person seeking to score excellent grades. Therefore, before you even put pen to paper, understand what research format is required.

Keep in mind that part of understanding the paper’s format is knowing what words to use and not to use. You can contact our trustful masters to get qualified assistance.

Research Thoroughly and Create an Outline

Whichever genetics research paper topics you decide to go with, the key to having excellent results is appropriately researching it. Therefore, embark on a journey to understand your genetics research paper topic by thoroughly studying it using resources from your school’s library and the internet.

Ensure you create an outline so that you can note all the useful genetic project ideas down. A research paper outline will help ensure that you don’t forget even one important point. It also enables you to organize your thoughts. That way, writing them down in the actual genetics research paper becomes smooth sailing. In other words, a genetics project outline is more like a sketch of the paper.

Other than the outline, it pays to have an excellent research strategy. In other words, instead of looking for information on any random source you come across, it would be wise to have a step-by-step process of looking for the research information.

For instance, you could start by reading your notes to see what they have to say about the topic you’ve chosen. Next, visit your school’s library, go through any books related to your genetics research paper topic to see whether the information on your notes is correct and for additional information on the topic. Note, you can visit the library either physically or via your school’s website. Lastly, browse educational sites such as Google Scholar, for additional information. This way, you’ll start your work with a bunch of excellent genetics project ideas, and at the same time, you’ll have enjoyed every step of the research process.

Get Down to Work

Now turn the genetics project ideas on your outline into a genetics research paper full of useful and factual information.

There is no denying writing a genetics research paper is one of the hardest parts of your studies. But with the above genetics topics and writing tips to guide you, it should be a tad easier. Good luck!

119 Genetics Research Topics You Must Know About

Put simply, Genetics is the study of genes and hereditary traits in living organisms. Knowledge in this field has gone up over time, and this is proportional to the amount of research.

Right from the DNA structure discovery, a lot more has come out into the open. There are so many genetics research topics to choose from because of the wide scope of research done in recent years.

Genetics is so dear to us since it helps us understand our genes and hereditary traits. In this guide, you will get to understand this subject more and get several topic suggestions that you can consider when looking for interesting genetics topics.

Writing a paper on genetics is quite intriguing nowadays. Remember that because there are so many topics in genetics, choosing the right one is crucial. It will help you cut down on research time and the technicality of selecting content for the topic. Thus, it would matter a lot if you confirmed whether or not the topic you’re choosing has relevant sources in plenty.

What Is Genetics?

Before we even go deeper into genetics topics for research papers, it is essential to have a basic understanding of what the subject entails.

Genetics is a branch of Biology to start with. It is mainly focused on the study of genetic variation, hereditary traits, and genes.

Genetics has relations with several other subjects, including biotechnology, medicine, and agriculture. In Genetics, we study how genes act on the cell and how they’re transmitted from a parent to the offspring. In modern Genetics, the emphasis is more on DNA, which is the chemical substance found in genes. Remember that Genetics cut across animals, insects, and plants – basically any living organism there is.

Tips On How To Write A Decent Research Paper On Genetics

When planning to choose genetics topics, you should also make time and learn how to research. After all, this is the only way you can gather the information that will help you come up with the content for the paper. Here are some tips that can bail you out whenever you feel stuck:

Choosing the topic, nonetheless, is not an easy thing for many students. There are just so many options present, and often, you get spoilt for choice. But note that this is an integral stage/process that you have to complete. Do proper research on the topic and choose the kind of information that you’d like to apply.

Choose a topic that has enough sources academically. Also, choosing interesting topics in genetics is a flex that can help you during the writing process.

On the web, there’s a myriad of information that often can become deceiving. Amateurs try their luck to put together several pieces of information in a bid to try and convince you that they are the authority on the subject. Many students become gullible to such tricks and end up writing poorly in Genetics.

Resist the temptation to look for an easy way of gaining sources/information. You have to take your time and dig up information from credible resources. Otherwise, you’ll look like a clown in front of your professor with laughable Genetics content.

Also, it is quite important that you check when your sources were updated or published. It is preferred and advised that you use recent sources that have gone under satisfactory research and assessment.

Also, add a few words to each on what you’re planning to discuss.Now, here are some of the top genetics paper topics that can provide ideas on what to write about.

Good Ideas For Genetics Topics

Here are some brilliant ideas that you can use as research paper topics in the Genetics field:

Is the knowledge of Genetics ahead of replication and research?
What would superman’s genetics be like?
DNA molecules and 3D printing – How does it work?
How come people living in mountainous regions can withstand high altitudes?
How to cross genes in distinct animals.
Does gene-crossing really help to improve breeds or animals?
The human body’s biggest intriguing genetic contradictions
Are we still far away from achieving clones?
How close are we to fully cloning human beings?
Can genetics really help scientists to secure various treatments?
Gene’s regulation – more details on how they can be regulated.
Genetic engineering and its functioning.
What are some of the most fascinating facts in the field of Genetics?
Can you decipher genetic code?
Cancer vaccines and whether or not they really work.
Revealing the genetic pathways that control how proteins are made in a bacterial cell.
How food affects the human body’s response to and connection with certain plants’ and animals’ DNA.

Hot Topics In Genetics

In this list are some of the topics that raise a lot of attention and interest from the masses. Choose the one that you’d be interested in:

The question of death: Why do men die before women?
Has human DNA changed since the evolution process?
How much can DNA really change?
How much percentage of genes from the father goes to the child?
Does the mother have a higher percentage of genes transferred to the child?
Is every person unique in terms of their genes?
How does genetics make some of us alike?
Is there a relationship between diets and genetics?
Does human DNA resemble any other animal’s DNA?
Sleep and how long you will live on earth: Are they really related?
Does genetics or a healthy lifestyle dictate how long you’ll live?
Is genetics the secret to long life on earth?
How much does genetics affect your life’s quality?
The question on ageing: Does genetics have a role to play?
Can one push away certain diseases just by passing a genetic test?
Is mental illness continuous through genes?
The relationship between Parkinson’s, Alzheimer’s and the DNA.

Molecular Genetics Topics

Here is a list of topics to help you get a better understanding of Molecular genetics:

Mutation of genes and constancy.
What can we learn more about viruses, bacteria, and multicellular organisms?
A study on molecular genetics: What does it involve?
The changing of genetics in bacteria.
What is the elucidation of the chemical nature of a gene?
Prokaryotes genetics: Why does this take a centre stage in the genetics of microorganisms?
Cell study: How this complex assessment has progressed.
What tools can scientists wield in cell study?
A look into the DNA of viruses.
What can the COVID-19 virus help us to understand about genetics?
Examining molecular genetics through chemical properties.
Examining molecular genetics through physical properties.
Is there a way you can store genetic information?
Is there any distinction between molecular levels and subcellular levels?
Variability and inheritance: What you need to note about living things at the molecular level.
The research and study on molecular genetics: Key takeaways.
What scientists can do within the confines of molecular genetics?
Molecular genetics research and experiments: What you need to know.
What is molecular genetics, and how can you learn about it?

Human Genetics Research Topics

Human genetics is an interesting field that has in-depth content. Some topics here will jog your brain and invoke curiosity in you. However, if you have difficulty writing a scientific thesis , you can always contact us for help.

Can you extend your life by up to 100% just by gaining more understanding of the structure of DNA?
What programming can you do with the help of DNA?
Production of neurotransmitters and hormones through DNA.
Is there something that you can change in the human body?
What is already predetermined in the human body?
Do genes capture and secure information on someone’s mentality?
Vaccines and their effect on the DNA.
What’s the likelihood that a majority of people on earth have similar DNA?
Breaking of the myostatin gene: What impact does it have on the human body?
Is obesity passed genetically?
What are the odds of someone being overweight when the rest of his lineage is obese?
A better understanding of the relationship between genetics and human metabolism.
The truths and myths engulfing human metabolism and genetics.
Genetic tests on sports performance: What you need to know.
An insight on human genetics.
Is there any way that you can prevent diseases that are transmitted genetically?
What are some of the diseases that can be passed from one generation to the next through genetics?
Genetic tests conducted on a person’s country of origin: Are they really accurate?
Is it possible to confirm someone’s country of origin just by analyzing their genes?

Current Topics in Genetics

A list to help you choose from all the most relevant topics:

DNA-altering experiments: How are scientists conducting them?
How important is it to educate kids about genetics while they’re still in early learning institutions?
A look into the genetics of men and women: What are the variations?
Successes and failures in the study of genetics so far.
What does the future of genetics compare to the current state?
Are there any TV series or science fiction films that showcase the future of genetics?
Some of the most famous myths today are about genetics.
Is there a relationship between genetics and homosexuality?
Does intelligence pass through generations?
What impact does genetics hold on human intelligence?
Do saliva and hair contain any genetic data?
What impact does genetics have on criminality?
Is it possible that most criminals inherit the trait through genetics?
Drug addiction and alcohol use: How close can you relate it to genetics?
DNA changes in animals, humans, and plants: What is the trigger?
Can you extend life through medication?
Are there any available remedies that extend a person’s life genetically?
Who can study genetics?
Is genetics only relevant to scientists?
The current approach to genetics study: How has it changed since ancient times?

Controversial Genetics Topics

Last, but definitely not least, are some controversial topics in genetics. These are topics that have gone through debate and have faced criticism all around. Here are some you can write a research paper about:

Gene therapy: Some of the ethical issues surrounding it.
The genetic engineering of animals: What questions have people raised about it?
The controversy around epigenetics.
The human evolution process and how it relates to genetics.
Gene editing and the numerous controversies around it.
The question on same-sex relations and genetics.
The use of personal genetic information in tackling forensic cases.
Gene doping in sports: What you need to know.
Gene patenting: Is it even possible?
Should gene testing be compulsory?
Genetic-based therapies and the cloud of controversy around them.
The dangers and opportunities that lie in genetic engineering.
GMOs and their impact on the health and welfare of humans.
At what stage in the control of human genetics do we stop to be human?
Food science and GMO.
The fight against GMOs: Why is it such a hot topic?
The pros and cons of genetic testing.
The debates around eugenics and genetics.
Labelling of foods with GMO: Should it be mandatory?
What really are the concerns around the use of GMOs?
The Supreme Court decision on the patent placed on gene discoveries.
The ethical issues surrounding nurses and genomic healthcare.
Cloning controversial issues.
Religion and genetics.
Behavior learning theories are pegged on genetics.
Countries’ war on GMOs.
Studies on genetic disorders.

Get Professional Help Online

Now that we have looked at the best rated topics in genetics, from interesting to controversial topics genetics, you have a clue on what to choose. These titles should serve as an example of what to select.

Nonetheless, if you need help with a thesis, we are available to offer professional and affordable thesis writing services . Our high quality college and university assignment assistance are available to all students online at a cheap rate. Get a sample to check on request and let us give you a hand when you need it most.

213 Genetics Research Topics & Essay Questions for College and High School

Genetics studies how genes and traits pass from generation to generation. It has practical applications in many areas, such as genetic engineering, gene therapy, gene editing, and genetic testing. If you’re looking for exciting genetics topics for presentation, you’re at the right place! Here are genetics research paper topics and ideas for different assignments.

🧬 TOP 7 Genetics Topics for Presentation 2024

🏆 best genetics essay topics, ❓ genetics research questions, 👍 good genetics research topics & essay examples, 🌟 cool genetics topics for presentation, 🌶️ hot genetics topics to write about, 🔎 current genetic research topics, 🎓 most interesting genetics topics.

Advantages and Disadvantages of Genetic Testing
The Importance of Heredity and Genetics
Cause and Effect of Genetically Modified Food
Should Parents Have the Right to Choose Their Children Based on Genetics?
Genetically Modified Pineapples and Their Benefits
Genetic and Environmental Impacts on Teaching Work
Simulating the Natural Selection and Genetic Drift
Link Between Obesity and Genetics Obesity affects the lives through limitations implemented on the physical activity, associated disorders, and even emotional pressure.
GMO Use in Brazil and Other Countries The introduction of biotechnology into food production was a milestone. Brazil is one of the countries that are increasingly using GMOs for food production.
Genetic Counseling for Cystic Fibrosis Some of the inherited genes may predispose individuals to specific health conditions like cystic fibrosis, among other inheritable diseases.
Environmental Ethics in Genetically Modified Organisms The paper discusses genetically modified organisms. Environmental ethics is centered on the ethical dilemmas arising from human interaction with the nonhuman domain.
Human Genetics: Multifactorial Traits This essay states that multifactorial traits in human beings are essential for distinguishing individual characteristics in a population.
The Concept of Epigenetics Epigenetics is a study of heritable phenotypic changes or gene expression in cells that are caused by mechanisms other than DNA sequence.
Genetic and Social Behavioral Learning Theories Learning and behavioral habits in human beings can be influenced by social, environmental and genetic factors. Genetic theory describes how genes help in shaping human behaviors.
The Potential Benefits of Genetic Engineering Genetic engineering is a new step in the development of the humans’ knowledge about the nature that has a lot of advantages for people in spite of its controversial character.
Genetic Engineering: Dangers and Opportunities Genetic engineering can be defined as: “An artificial modification of the genetic code of an organism. It changes radically the physical nature of the being in question.
Restricting the Volume of Sale of Fast Foods and Genetically Modified Foods The effects of fast foods and genetically modified foods on the health of Arizona citizens are catastrophic. The control of such outlets and businesses is crucial.
Genetic Modifications: Advantages and Disadvantages Genetic modifications of fruits and vegetables played an important role in the improvement process of crops and their disease resistance, yields, eating quality and shelf life.
Plant Genetic Engineering: Genetic Modification Genetic engineering is the manipulation of the genes of an organism by completely altering the structure of the organism.
DNA and the Birth of Molecular Genetics Molecular genetics is critical in studying traits that are passed through generations. The paper analyzes the role of DNA to provide an ample understanding of molecular genetics.
Decision Tree Analysis and Genetic Algorithm Methods Application in Healthcare The paper investigates the application of such methods of data mining as decision tree analysis and genetic algorithm in the healthcare setting.
Ban on Genetically Modified Foods Genetically modified (GM) foods are those that are produced with the help of genetic engineering. Such foods are created from organisms with changed DNA.
Family Pedigree, Human Traits, and Genetic Testing Genetic testing allows couples to define any severe genes in eight-cell embryos and might avoid implanting the highest risk-rated ones.
Genetically Modified Food Safety and Benefits Today’s world faces a problem of the shortage of food supplies to feed its growing population. The adoption of GM foods can solve the problem of food shortage in several ways.
Gene Transfer and Genetic Engineering Mechanisms This paper discusses gene transfer mechanisms and the different genetic engineering mechanisms. Gene transfer, a natural process, can cause variation in biological features.
Convergent Evolution, Genetics and Related Structures This paper discusses the concept of convergent evolution and related structures. Convergent evolution describes the emergence of analogous or similar traits in different species.
Type 1 Diabetes in Children: Genetic and Environmental Factors The prevalence rate of type 1 diabetes in children raises the question of the role of genetic and environmental factors in the increasing cases of this illness.
Genetically Modified Fish: The Threats and Benefits This article’s purpose is to evaluate possible harm and advantages of genetically modified fish. For example, the GM fish can increase farms’ yield.
Darwin’s Theory of Evolution: Impact of Genetics New research proved that genetics are the driving force of evolution which causes the revision of some of Darwin’s discoveries.
Cystic Fibrosis: Genetic Disorder Cystic fibrosis, also referred to as CF, is a genetic disorder that can affect the respiratory and digestive systems.
Technology of Synthesis of Genetically Modified Insulin The work summarizes the technology for obtaining genetically modified insulin by manipulating the E. coli genome.
Advantages of Using Genetically Modified Foods Genetic modifications of traditional crops have allowed the expansion of agricultural land in areas with adverse conditions.
Literature Review: Acceptability of Genetic Engineering The risks and benefits of genetic engineering must be objectively evaluated so that modern community could have a better understanding of this problem
Genetics and Autism Development Autism is associated with a person’s genetic makeup. This paper gives a detailed analysis of this condition and the role of genetics in its development.
Genetics of Developmental Disabilities The aim of the essay is to explore the genetic causes of DDs, especially dyslexia, and the effectiveness of DNA modification in the treatment of these disorders.
GMO: Some Peculiarities and Associated Concerns Genetically modified organisms are created through the insertion of genes of other species into their genetic codes.
Genetic Counseling and Hypertension Risks This paper dwells upon the peculiarities of genetic counseling provided to people who are at risk of developing hypertension.
The Perspectives of Genetic Engineering in Various Fields Genetic engineering can be discussed as having such potential benefits for the mankind as improvement of agricultural processes, environmental protection, resolution of the food problem.
Genetically Modified Foods and Their Impact on Human Health Genetically modified food has become the subject of discussion. There are numerous benefits and risks tied to consumption of genetically modified foods.
Genetics and Evolution: Mutation, Selection, Gene Flow and Drift Evolutionary genetics deals with mechanisms that explain the presence and maintenance of traits responsible for genetic variations.
How Much Do Genetics Affect Us?
What Can Livestock Breeders Learn From Conservation Genetics and Vice Versa?
How Do Genetics Affect Caffeine Tolerance?
How Dolly Sheep Changed Genetics Forever?
What Is the Nature and Function of Genetics?
What Are the Five Branches of Genetics?
How Does Genetics Affect the Achievement of Food Security?
Are Owls and Larks Different in Genetics When It Comes to Aggression?
How Do Neuroscience and Behavioral Genetics Improve Psychiatric Assessment?
How Does Genetics Influence Human Behavior?
What Are Three Common Genetics Disorders?
Can Genetics Cause Crime or Are We Presupposed?
What Are Examples of Genetics Influences?
How Do Genetics Influence Psychology?
What Traits Are Influenced by Genetics?
Why Tampering With Our Genetics Will Be Beneficial?
How Genetics and Environment Affect a Child’s Behaviors?
Which Country Is Best for Genetics Studies?
How Does the Environment Change Genetics?
Can Crop Models Identify Critical Gaps in Genetics, Environment, and Management Interactions?
How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?
Can You Change Your Genetics?
How Old Are European Genetics?
Will Benchtop Sequencers Resolve the Sequencing Trade-off in Plant Genetics?
What Can You Study in Genetics?
What Are Some Genetic Issues?
Does Genetics Matter for Disease-Related Stigma?
How Did the Drosophila Melanogaster Impact Genetics?
What Is a Genetics Specialist?
Will Genetics Destroy Sports?
Exploring ADHD: Genetics, Environment, and Brain Changes Attention deficit hyperactivity disorder is the most prevalent child behavioral disorder characterized by inattention, hyperactivity, and impulsivity.
Down’s Syndrome as a Genetic Disorder Many people are born with genetic diseases that manifest themselves in one way or another throughout their lives. One of these abnormalities is Down’s syndrome.
Addiction: Genetic, Environmental, and Psychological Factors Addiction: the role of dopamine and its impact on the brain’s reward system exacerbates addiction and highlights the need for a comprehensive approach.
Procreative Beneficence: Technological Developments in Genetics Technological developments in genetics have revolutionized procreation by allowing parents to choose the most intelligent genes for their offspring.
Genetic Technologies for Pathogen Identification The paper states that a genotype represents a set of genes and determines the organism’s phenotype by promoting the development of certain traits.
Epigenetics as the Phenomenon and Its Examples Epigenetics, or epigenomics, is the study of how the expression of genes that do not presuppose irreversible alterations in the underlying DNA sequence changes.
Aspects of the Genetic Diseases Genetic diseases are disorders that happen through mutations that occur in the human body. They can be monogenic, multifactorial, and chromosomal.
Genetics: When Nurture Becomes Nature The paper aims to review the environmental and dietary aspects of epigenetics and show how the research can be useful in understanding genetics.
Is ADHD Genetically Passed Down to Family Members? Genetic correlations between such qualities as hyperactivity and inattention allowed us to define ADHD as a spectrum disorder rather than a unitary one.
Alzheimer’s Disease: Genetic Risk and Ethical Considerations Alzheimer’s disease is a neurodegenerative disease that causes brain shrinkage and the death of brain cells. It is the most prevalent form of dementia.
Behavioral Genetics in “Harry Potter” Books The reverberations of the Theory of Behavioral Genetics permeate the Harry Potter book series, enabling to achieve the comprehension of characters and their behaviors.
Environmental Impact of Genetically Modified Crop In 1996, the commercial use of genetically modified (GM) crop production techniques had increasingly been accepted by many farmers.
Nutrition: Obesity Pandemic and Genetic Code The environment in which we access the food we consume has changed. Unhealthy foods are cheaper, and there is no motivation to eat healthily.
Relation Between Genetics and Intelligence Intelligence is a mental ability to learn from experience, tackle issues and use knowledge to adapt to new situations and the factor g may access intelligence of a person.
Genetics in Diagnosis of Diseases Medical genetics aims to study the role of genetic factors in the etiology and pathogenesis of various human diseases.
The Morality of Selective Abortion and Genetic Screening The paper states that the morality of selective abortion and genetic screening is relative. This technology should be made available and legal.
Does Genetic Predisposition Affect Learning in Other Disciplines? This paper aims to examine each person’s ability to study a discipline for which there is no genetic ability and to understand how effective it is.
Detection of Genetically Modified Products Today, people are becoming more concerned about the need to protect themselves from the effects of harmful factors and to buy quality food.
Genetically Modified Organisms Solution to Global Hunger It is time for the nations to work together and solve the great challenge of feeding the population by producing sufficient food and using fewer inputs.
Genetic Engineering: Cloning With Pet-28A Embedding genes into plasmid vectors is an integral part of molecular cloning as part of genetic engineering. An example is the cloning of the pectate lyase gene.
Researching of Genetic Engineering DNA technology entails the sequencing, evaluation and cut-and-paste of DNA. The following paper analyzes the historical developments, techniques, applications, and controversies.
Genetically Modified Crops: Impact on Human Health The aim of this paper is to provide some information about genetically modified crops as well as highlight the negative impacts of genetically modified soybeans on human health.
Genetic Engineering Biomedical Ethics Perspectives Diverse perspectives ensure vivisection, bio, and genetic engineering activities, trying to deduce their significance in evolution, medicine, and society.
Down Syndrome: The Genetic Disorder Down syndrome is the result of a glandular or chemical disbalance in the mother at the time of gestation and of nothing else whatsoever.
Genetics of Personality Disorders The genetics of different psychological disorders can vary immensely; for example, the genetic architecture of schizophrenia is quite perplexing and complex.
Labeling of Genetically Modified Products Regardless of the reasoning behind the labeling issue, it is ethical and good to label the food as obtained from genetically modified ingredients for the sake of the consumers.
Genetic Technologies in the Healthcare One area where genetic technology using DNA works for the benefit of society is medicine, as it will improve the treatment and management of genetic diseases.
Are Genetically Modified Organisms Really That Bad? Almost any food can be genetically modified: meat, fruits, vegetables, etc. Many people argue that consuming products, which have GMOs may cause severe health issues.
Discussion of Genetic Testing Aspects The primary aim of the adoption process is to ensure that the children move into a safe and loving environment.
Ethical Concerns on Genetic Engineering The paper discusses Clustered Regularly Interspaced Short Palindromic Repeats technology. It is a biological system for modifying DNA.
The Normal Aging Process and Its Genetic Basis Various factors can cause some genetic disorders linked to premature aging. The purpose of this paper is to talk about the genetic basis of the normal aging process.
Defending People’s Rights Through GMO Labels Having achieved mandatory labeling of GMOs, the state and other official structures signal manufacturers of goods about the need to respect customers’ rights.
Medicine Is Not a Genetic Supermarket Together with the development of society, medicine also develops, but some people are not ready to accept everything that science creates.
Epigenetics: Definition and Family History Epigenetics refers to the learning of fluctuations in creatures induced by gene expression alteration instead of modification of the ‘genetic code itself.
Genetically Modified Organisms in Aquaculture Genetically Modified Organisms are increasingly being used in aquaculture. They possess a unique genetic combination that makes them uniquely suited to their environment.
Genetic Modification of Organisms to Meet Human Needs Genetic modification of plants and animals for food has increased crop yields as the modified plants and animals have more desirable features such as better production.
Discussion of Epigenetics Meanings and Aspects The paper discusses epigenetics – the study of how gene expression takes place without changing the sequence of DNA.
Mendelian Genetics and Chlorophyll in Plants This paper investigates Mendelian genetics. This lab report will examine the importance of chlorophyll in plants using fast plants’ leaves and stems.
Genetic Testing and Bill of Rights and Responsibilities Comparing the Patient Bill of Rights or Patient Rights and Responsibilities of UNMC and the Nebraska Methodist, I find that the latter is much broader.
Genetically Modified Products: Positive and Negative Sides This paper considers GMOs a positive trend in human development due to their innovativeness and helpfulness in many areas of life, even though GMOs are fatal for many insects.
The role of genes in our food preferences.
The molecular mechanisms of aging and longevity.
Genomic privacy: ways to protect genetic information.
The effects of genes on athletic performance.
CRISPR-Cas9 gene editing: current applications and future perspectives.
Genetic underpinnings of human intelligence.
The genetic foundations of human behavior.
The role of DNA analysis in criminal justice.
The influence of genetic diversity on a species’ fate.
Genetic ancestry testing: the process and importance.
Overview of African Americans’ Genetic Diseases African Americans are more likely to suffer from certain diseases than white Americans, according to numerous studies.
Genetic Linkage Disorders: An Overview A receptor gene in the human chromosome 9 is the causative agent of most blood vessel disorders. Moreover, blood vessel disorders are the major cause of heart ailments.
Natural Selection and Genetic Variation The difference in the genetic content of organisms is indicative that certain group of organisms will stay alive, and effectively reproduce than other organisms residing in the same environment.
Genetically Modified Foods: How Safe are they? This paper seeks to address the question of whether genetically modified plants meant for food production confer a threat to human health and the environment.
The Genetic Material Sequencing This experiment is aimed at understanding the real mechanism involved in genetic material sequencing through nucleic acid hybridization.
Genetically Modified Organisms in Human Food This article focuses on Genetically Modified Organisms as they are used to produce human food in the contemporary world.
Genetics and Public Health: Disease Control and Prevention Public health genomics may be defined as the field of study where gene sequences can be used to benefit society.
Genetic Disorder Cystic Fibrosis Cystic fibrosis is a genetic disorder. The clinical presentation of the disease is evident in various organs of the body as discussed in this paper.
The Study of the Epigenetic Variation in Monozygotic Twins The growth and development of an organism result in the activation and deactivation of different parts due to chemical reactions at strategic periods and locations
Human Genome and Application of Genetic Variations Human genome refers to the information contained in human genes. The Human Genome Project (HGP) focused on understanding genomic information stored in the human DNA.
Genetic Alterations and Cancer The paper will discuss cancer symptoms, causes, diagnosis, treatment, side-effects of treatment, and also its link with a genetic alteration.
Saudi Classic Aniridia Genetic and Genomic Analysis This research was conducted in Saudi Arabia to determine the genetic and genomic alterations that underlie classic anirida.
What Makes Humans Mortal Genetically? The causes of aging have been studied and debated about by various experts for centuries, there multiple views and ideas about the reasons of aging and.
Genetic Screening and Testing The provided descriptive report explains how genetic screening and testing assists clinicians in determining cognitive disabilities in babies.
Neurobiology: Epigenetics in Cocaine Addiction Studies have shown that the addiction process is the interplay of many factors that result in structural modifications of neuronal pathways.
Genetic (Single Nucleotide Polymorphisms) Analysis of Genome The advancement of the SNP technology in genomic analysis has made it possible to achieve cheap, effective, and fast methods for analyzing personal genomes.
Genetic Tests: Pros and Cons Genetic testing is still undergoing transformations and further improvements, so it may be safer to avoid such procedures under certain circumstances.
Case on Preserving Genetic Mutations in IVF In the case, a couple of a man and women want to be referred to an infertility specialist to have a procedure of in vitro fertilization (IVF).
Race: Genetic or Social Construction One of the most challenging questions the community faces today is the following: whether races were created by nature or society or not.
Huntington’s Chorea Disease: Genetics, Symptoms, and Treatment Huntington’s chorea disease is a neurodegenerative heritable disease of the central nervous system that is eventually leading to uncontrollable body movements and dementia.
Genetics: A Frameshift Mutation in Human mc4r This article reviews the article “A Frameshift Mutation in Human mc4r Is Associated With Dominant Form of Obesity” published by C. Vaisse, K. Clement, B. Guy-Grand & P. Froguel.
DNA Profiling: Genetic Variation in DNA Sequences The paper aims to determine the importance of genetic variation in sequences in DNA profiling using specific techniques.
Genetic Diseases: Hemophilia This article focuses on a genetic disorder such as hemophilia: causes, symptoms, history, diagnosis, and treatment.
Genetics: Gaucher Disease Type 1 The Gaucher disease type 1 category is a genetically related complication in which there is an automatic recession in the way lysosomes store some important gene enzymes.
Genetic Science Learning Center This paper shall seek to present an analysis of sorts of the website Learn Genetics by the University of Utah.
Benefits of Genetic Engineering The potential increase of people’s physical characteristics and lifespan may be regarded as another advantage of genetic engineering.
What Is Silencer Rna in Genetics RNA silencing is an evolutionary conserved intracellular surveillance system based on recognition. RNA silencing is induced by double-stranded RNA sensed by the enzyme Dicer.
Genetic Testing and Privacy & Discrimination Issues Genetic testing is fraught with the violation of privacy and may result in discrimination in employment, poor access to healthcare services, and social censure.
Genetics or New Pharmaceutical Article Within the Last Year Copy number variations (CNVs) have more impacts on DNA sequence within the human genome than single nucleotide polymorphisms (SNPs).
Genetic Disorders: Diagnosis, Screening, and Treatment Chorionic villus is a test of sampling done especially at the early stages of pregnancy and is used to identify some problems which might occur to the fetus.
Research of Genetic Disorders Types This essay describes different genetic disorders such as hemophilia, turner syndrome and sickle cell disease (SCD).
Genetic Mechanism of Colorectal Cancer Colorectal Cancer (CRC) occurrence is connected to environmental factors, hereditary factors, and individual ones.
Isolated by Genetics but Longing to Belong The objective of this paper is to argue for people with genetic illnesses to be recognized and appreciated as personages in all institutions.
Genetic Association and the Prognosis of Phenotypic Characters The article understudy is devoted to the topic of genetic association and the prognosis of phenotypic characters. The study focuses on such a topic as human iris pigmentation.
PiggyBac Transposon System in Genetics Ideal delivery systems for gene therapy should be safe and efficient. PB has a high transposition efficiency, stability, and mutagenic potential in most mammalian cell lines.
A Career in Genetics: Required Skills and Knowledge A few decades ago, genetics was mostly a science-related sphere of employment. People with a degree in genetics can have solid career prospects in medicine and even agriculture.
Genetic Factors as the Cause of Anorexia Nervosa Genetic predisposition currently seems the most plausible explanation among all the proposed etiologies of anorexia.
Bioethical Issues in Genetic Analysis and Manipulations We are currently far from a point where we can claim that we should be providing interventions to some and not others due to their genetic makeup.
Personality Is Inherited Principles of Genetics The present articles discusses the principles of genetics, and how is human temperament and personality formed.
Impacts of Genetic Engineering of Agricultural Crops In present days the importance of genetic engineering grew due to the innovations in biotechnologies and Sciences.
Genetic foundations of rare diseases.
Genetic risk factors for neurodegenerative disorders.
Inherited cancer genes and their impact on tumor development.
Genetic variability in drug metabolism and its consequences.
The role of genetic and environmental factors in disease development.
Genomic cancer medicine: therapies based on tumor DNA sequencing.
Non-invasive prenatal testing: benefits and challenges.
Genetic basis of addiction.
The origins of domestication genes in animals.
How can genetics affect a person’s injury susceptibility?
The Effects of Genetic Modification of Agricultural Products Discussion of the threat to the health of the global population of genetically modified food in the works of Such authors as Jane Brody and David Ehrenfeld.
Genetic Engineering in Food and Freshwater Issues The technology of bioengineered foods, genetically modified, genetically engineered, or transgenic crops, will be an essential element in meeting the challenging population needs.
Genetic Engineering and Religion: Designer Babies The current Pope has opposed any scientific procedure, including genetic engineering, in vitro fertilization, and diagnostic tests to see if babies have disabilities.
Op-ED Genetic Engineering: The Viewpoint The debate about genetic engineering was started more than twenty years ago and since that time it has not been resolved
Genetically Modified Food as a Current Issue GM foods are those kinds of food items that have had their DNA changed by usual breeding; this process is also referred to as Genetic Engineering.
All About the Role of Genetic Engineering and Biopiracy The argument whether genetically engineered seeds have monopolized the market in place of the contemporary seeds has been going on for some time now.
Genetic Engineering and Cloning Controversy Genetic engineering and cloning are the most controversial issues in modern science. The benefits of cloning are the possibility to treat incurable diseases and increase longevity.
Biotechnology: Methodology in Basic Genetics The material illustrates the possibilities of ecological genetics, the development of eco-genetical models, based on the usage of species linked by food chain as consumers and producers.
Genetics Impact on Health Care in the Aging Population This paper briefly assesses the impact that genetics and genomics can have on health care costs and services for geriatric patients.
Concerns Regarding Genetically Modified Food It is evident that genetically modified food and crops are potentially harmful. Both humans and the environment are affected by consequences as a result of their introduction.
Family Genetic History and Planning for Future Wellness The patient has a family genetic history of cardiac arrhythmia, allergy, and obesity. These diseases might lead to heart attacks, destroy the cartilage and tissue around the joint.
Personal Genetics and Risks of Diseases Concerning genetics, biographical information includes data such as ethnicity. Some diseases are more frequent in specific populations as compared to others.
Genetic Predisposition to Alcohol Dependence and Alcohol-Related Diseases The subject of genetics in alcohol dependence deserves additional research in order to provide accurate results.
Genetically-Modified Fruits, Pesticides, or Biocontrol? The main criticism of GMO foods is the lack of complete control and understanding behind GMO processes in relation to human consumption and long-term effects on human DNA.
Genetic Variants Influencing Effectiveness of Exercise Training Programmes “Genetic Variants Influencing Effectiveness of Exercise Training Programmes” studies the influence of most common genetic markers that indicate a predisposition towards obesity.
Eugenics, Human Genetics and Their Societal Impact Ever since the discovery of DNA and the ability to manipulate it, genetics research has remained one of the most controversial scientific topics of the 21st century.
Genetic Interference in Caenorhabditis Elegans The researchers found out that the double-stranded RNA’s impact was not only the cells, it was also on the offspring of the infected animals.
Start Up Company: Genetically Modified Foods in China The aim of establishing the start up company is to develop the scientific idea of increasing food production using scientific methods.
Community Health Status: Development, Gender, Genetics Stage of development, gender and genetics appear to be the chief factors that influence the health status of the community.
Homosexuality as a Genetic Characteristic The debate about whether homosexuality is an inherent or social parameter can be deemed as one of the most thoroughly discussed issues in the contemporary society.
Autism Spectrum Disorder in Twins: Genetics Study Autism spectrum disorder is a behavioral condition caused by genetic and environmental factors. Twin studies have been used to explain the hereditary nature of this condition.
Why Is the Concept of Epigenetics So Fascinating? Epigenetics has come forward to play a significant role in the modern vision of the origin of illnesses and methods of their treatment, which results in proving to be fascinating.
Epigenetics and Its Effect on Physical and Mental Health This paper reviews a research article and two videos on epigenetics to developing an understanding of the phenomenon and how it affects individuals’ physical and mental health.
Genomics, Genetics, and Nursing Involvement The terms genomics and genetics refer to the study of genetic material. In many cases, the words are erroneously used interchangeably.
Genetic and Genomic Healthcare: Nurses Ethical Issues Genomic medicine is one of the most significant ways of tailoring healthcare at a personal level. This paper will explore nursing ethics concerning genetic information.
Medical and Psychological Genetic Counseling Genetic counseling is defined as the process of helping people understand and adapt to the medical, psychological, and familial implications of genetic contributions to disease.
Patent on Genetic Discoveries and Supreme Court Decision Supreme Court did not recognize the eligibility of patenting Myriad Genetics discoveries due to the natural existence of the phenomenon.
Genetic Testing, Its Background and Policy Issues This paper will explore the societal impacts of genetic research and its perceptions in mass media, providing argumentation for support and opposition to the topic.
Genetically Modified Organisms and Future Farming There are many debates about benefits and limitations of GMOs, but so far, scientists fail to prove that the advantages of these organisms are more numerous than the disadvantages.
Mitosis, Meiosis, and Genetic Variation According to Mendel’s law of independent assortment, alleles for different characteristics are passed independently from each other.
Labeling Food With Genetically Modified Organisms The wide public has been concerned about the issue of whether food products with genetically modified organisms should be labeled since the beginning of arguments on implications.
Diabetes Genetic Risks in Diagnostics The introduction of the generic risks score in the diagnosis of diabetes has a high potential for use in the correct classification based on a particular type of diabetes.
Residence and Genetic Predisposition to Diseases The study on the genetic predisposition of people to certain diseases based on their residence places emphasizes the influence of heredity.
Eugenics, Human Genetics and Public Policy Debates Ethical issues associated with human genetics and eugenics have been recently brought to public attention, resulting in the creation of peculiar public policy.
Value of the Epigenetics Epigenetics is a quickly developing field of science that has proven to be practical in medicine. It focuses on changes in gene activity that are not a result of DNA sequence mutations.
Genetics Seminar: The Importance of Dna Roles DNA has to be stable. In general, its stability becomes possible due to a large number of hydrogen bonds which make DNA strands more stable.
Genetically Modified Organisms: Position Against Genetically modified organisms are organisms that are created after combining DNAs of different species to come up with a transgenic organism.
Genetically Modified Organisms: Pros and Cons Genetically modified organisms are organisms that are created after combining DNA from a different species into an organism to come up with a transgenic organism.
Genetically Modified Organisms and Their Benefits Scientists believe GMOs can feed everyone in the world. This can be achieved if governments embrace the use of this new technology to create genetically modified foods.
Food Science and Technology of Genetic Modification Genetically modified foods have elicited different reactions all over the world with some countries banning its use while others like the United States allowing its consumption.
How Much can We Control Our Genetics, at What Point do We Cease to be Human? The branch of biology that deals with variation, heredity, and their transmission in both animals and the plant is called genetics.
Genetic Engineering: Gene Therapy The purpose of the present study is to discover just what benefits gene therapy might have to offer present and future generations.

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These essay examples and topics on Genetics were carefully selected by the StudyCorgi editorial team. They meet our highest standards in terms of grammar, punctuation, style, and fact accuracy. Please ensure you properly reference the materials if you’re using them to write your assignment.

This essay topic collection was updated on June 22, 2024 .

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126 High Quality Genetics Research Topics You Can Use

Most students look for genetics research topics to write about when pursuing biology studies. Developing exciting titles in this subject isn’t everyone’s favorite. Perhaps, that’s because of the technicality of this subject. This article lists interesting genetics topics for learners at different educational levels to consider for their papers. This list is essential because many learners struggle to develop or find titles for their essays but end with ideas that don’t interest educators.

What Is Genetics?

Genetics is the study of genes. In this field, scientists study how individuals pass down genes and traits from one generation to another. Genes carry vital information that impacts an individual’s appearance, health, and personality.

When writing research papers about genetics topics, students should follow several steps to create winning pieces. Here’s how to write an excellent essay in this field.

Pick a topic: Select a topic you’re comfortable researching, analyzing, and writing about to provide relevant and accurate information. Find sources and gather information: Look for reliable information sources, including peer-reviewed articles, journals, and professional books. Also, you can use websites with reliable information about genetics. Gather as much relevant information and analyze it. Outline the paper: Develop a structure to guide your research and writing. A typical outline should have an introduction, body, and conclusion. Write the paper: Use the outline and information from your research to write the essay. Ensure that your ideas and information flow logically.

The first and most vital step is selecting a good topic. Unfortunately, some learners have difficulties picking titles for their papers. Fortunately, the following list has a topic idea you will likely enjoy exploring. Use our online research paper writing servic e and get your paper done fast.

Interesting Topics In Genetics

Perhaps, you’re looking for an exciting title for your genetics paper. If so, this category has an ideal you will find exciting to explore.

How does genetic variation impact the evolution of species?
How do genes influence behavior and development?
What role do genes play in disease susceptibility?
How does the environment interact with genes to influence phenotype?
How can we use genetics to improve crop plants or livestock?
What is the impact of genetic engineering on society?
How will the human genome project impact medicine?
What ethical considerations are there in genetics research?
How can we use genetics to predict individual risk for disease?
What are the implications of personalized medicine?
How accurate is genetic engineering?
The bioethical and legal aspects of custom medicine based on the genetic composition
The diagnostic challenge of newborns with heritable protein C deficiency
Epithelial polarity in mammals and flies
Risk factors contributions and medical care to trends in cardiovascular mortality
Does cloning limit or increase biological diversity
Understanding oculopharyngeal muscular dystrophy- is it an under-diagnosed disease?
Imputation-based analysis- Quantitative traits and candidate regions
Loss-of-function variants- A survey of human protein-coding genes
Exploring DNA structural motifs’ thermodynamics

Explore any of these titles in your research, and your educator will find your paper exciting to read.

Controversial Topics In Genetics

Most people find controversial genetics topics exciting to read. Therefore, you can capture your educator’s attention by choosing and investigating a controversial idea in this study field. Here are such ideas to consider.

Can animal cloning lead to health problems for humans?
Is conducting maternal spindle transfer ethical?
Is pronuclear transfer possible without causing mitochondrial disease in the embryo?
Who decides the typical traits and which constitutes a disorder or disability?
What are the ethical implications of improving human qualities like intelligence, height, and athletic ability?
Is it ethical for doctors to alter germline traits using gene therapy?
How honest are gene therapy’s protocol guidelines?
Is changing a particular gene’s regulation ethical?
Gene therapy ethics when curing genetic disease in a fetus
How CRISPR-Cas9 gene editing affects a person’s germ line
The ethics of genetic engineering
The impact of genetic engineering on society
The potential for abuse with genetic engineering
The safety of genetically modified foods
The regulation of genetic engineering
The effect of genetic engineering on the environment
The future of genetic engineering
Is genetics the basis of depression?
Can addictive substances change human genes?
Can humans beat aging by altering genes?

These are controversial topics genetics students can find worth exploring. Nevertheless, prepare to research extensively to compose a winning paper about any of these ideas.

Human Genetics Topics For Research Papers

Human genetics entails studying inheritance in human beings. Here are some of the exciting human genetics topics for research papers.

The Human Genome Project and its significance for understanding human genetics.
Chromosomal abnormalities and their effects on human health.
The role of genes in human development and behavior.
The ethical implications of genetic testing and engineering.
The impact of new technologies on the study of human genetics.
The potential uses of genetic information in the diagnosis and treatment of disease.
The social and economic implications of genetic discrimination.
The role of genetics in predicting individual risk for common diseases.
The impact of advances in genomic research on our understanding of human evolution.
The role of genetics in human identity and individuality
The link between human gene changes and diseases
Genes coordination in human development
How a fertilized egg directs the entire organism’s formation
How gene editing to fix gene defects affects a human being
How genetic disorders impact the heart’s pathological development
Heritable genetic changes’ role in cardiovascular genetics
How somatic mutations enhance tumor metastases
How inherited genetic changes affect a person
Human body processes that affect RNA and DNA sequencing
How genetic mutations disrupt the normal cell proliferation regulation occurs in cancer

Consider these exciting human genetics topics if you find this sub-field exciting. Nevertheless, take the time to find sufficient and relevant information to write a comprehensive paper.

Molecular Genetics Topics

Molecular genetics is a biology sub-field addressing how different DNA molecule structures manifest in variations among organisms. Here are molecular genetics research paper topics to consider for your project.

Disseminating superior genetics into a commercial population
Analyzing linked genetic markets causing phenotypes differences
Exploring various genes’ responses to environmental stressors
How computer simulation affects molecular genetics
Macromolecules that are vital in biological inheritance
Molecular biology application in DNA forensics
How the hereditary mechanism discovery impacted molecular genetics
Tracing the molecular genetics origins from the 1930s
Discussing double-helical structure in DNA molecule
Ways of producing several copies of a DNA piece in the lab
What more can humans possibly learn about DNA?
How DNA determines the body structure
DNA and terminal illness- Is there a connection?
Does NDA sequencing have room for more?
Describe and outline the latest molecular cancer genetics developments
Explain genetic factors that enhance cancer susceptibility
Are bacteria a genetic system?
DNA and heredity- What’s the connection?
Describe the shortcomings and potentials of stem cells
Molecular techniques- Analyzing RNA, DNA, and proteins

Please select one of these titles and develop it into an exciting paper. Nevertheless, prepare to research extensively to fill your report with valuable information.

Current Topics In Genetics

Genetics research has a fascinating landscape with many current topics ripe for exploration. Here are some of the exciting contemporary ideas for research in genetics.

Man versus bat’s molecular structure
Genomics companies chasing after IPO- What are the impacts?
5G technology and how it affects the human genome
Exploring the human microbiome evolution
RNA binding and its role in leukemia treatment
Analyzing the double-stranded RNA
RNA-binding proteins characteristics
Exploring the potential use of gene editing in treating COVID-19
How drugs development and genes study relate
How social engineering affects genetics
Differentiating non-ethical and ethical gene therapy
Gene therapy could make it for the rich people
Why do people do gene testing under false names or anonymously?
Insurers should force individuals to undergo testing
Does euthanasia apply in the case of diseases?
Who should know about different genetic disorders?
Is genetic screening an interference with a person’s privacy?
Ethical implications of newborn’s prenatal screening
Can gene therapy treat a disease?
Can gene therapy make people not accept people that are different?

These are good genetics paper topics for learners at various educational levels, especially if they want to write about the latest development in this field.

Hot Topics In Genetics

Perhaps, while thinking “I must do my term paper” you’re looking for topics that most people will want to read about and understand your viewpoint. In that case, here are genetics research paper topics to consider.

Investigating critical molecules in genetic bone disease and bone development
Intracellular traffic jams in genetics- Studying the multi-organellar
Substance dependence and genetics- Is there a connection?
Hereditary ovarian and breast cancers- Exploring preventive measures and causes
Exploring gene composition in breast cancer and estrogen metabolism pathway
Discuss cancer genetics and the cycle of the Eukaryotic cell
Critical research on genetic elements that scientists can transport
Genetic challenges in human diseases and RNA metabolism
Genetic factors that cause human type 1 diabetes
Approaching the relationship between human obesity and genetic susceptibility
Is growing human organs morally upright and ethical?
Human cloning science- Exploring its development and history
Drug addiction and gene alteration
Are genetically modified foods safe for animal and human consumption?
Exploring fetus and genetic diagnosis
DNA structure analysis from the genetic perspective

These are hot titles to explore in research. But like those in the other section, students must research each idea extensively to write high-quality papers. Contact us with a “ do my research paper ” request and get a winning paper done by professional writer.

Genetics Topics For Presentation

The genetics subject can be complex and broad. Therefore, choosing unique topics in genetics can benefit the learners’ presentations. Here are sample topics to consider for your presentation.

The Genetic impact of neurological and terminal diseases
Genetic engineering- What are the pros and cons
Can humans create an artificial gene using synthetic chromosomes?
Will cloning follow genetic engineering and research?
The significance and complexity of gene mutation
The advantages and unlimited potential of human genetics
What does an individual’s DNA analysis say about their genetics?
Is conducting genetic testing necessary?
Is genes’ patent ownership ethical?
Can humans isolate and eliminate hereditary conditions with genetic research?

This list has at least one example of a topic in this study field that you might want to explore. However, pick a title you will comfortably work with and deliver a quality paper that will prompt the educator to award you the top grade.

Get Professional Help With Research Paper

Maybe you have a title but no time to write a winning paper. Perhaps you’ve realized that you need thesis help to compose medical term papers that will impress the educator and earn you the desired grade. In that case, contact us for the best-rated research paper assistance. We offer affordable writing services to learners across educational levels. Contact us now for cheap but quality online help with your research project.

Genetics Research Paper Topics

Biotechnology
Birth defects
Clone and cloning
Genetic disorders
Genetic engineering
Human Genome Project
Mendelian laws of inheritance
Nucleic acid

The History of Genetics

Humans have known about hereditary characteristics for thousands of years. That knowledge has been used for the improvement of domestic plants and animals. Until the late nineteenth century, however, that knowledge had been gained by trial-and-error experiments. The modern science of genetics began with the pioneering work of the Austrian monk and botanist Gregor Mendel (1822–1884).

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Mendel studied the genetic characteristics of pea plants. He was interested in finding out how certain traits, such as flower color and plant height, were passed on from generation to generation. During his lifetime, he studied dozens of generations of plants of all sizes, shapes, and colors. As a result of his research, Mendel was able to state a few basic laws describing the way genetic traits are inherited. He also came to the conclusion that there must be a specific biological unit responsible for the transmission of genetic traits. He called that unit a factor. Mendel’s “factors” were later given the name of genes.

Without question, Mendel was the father of the modern science of genetics. One of the great ironies of history, however, was that his discoveries were lost for more than three decades. Then, in the early 1900s, Mendel’s research was rediscovered almost simultaneously by three different biologists, the Dutch botanist Hugo de Vries (1848–1935), the German botanist Karl F. J. Correns (1864–1933), and the Austrian botanist Erich Tschermak von Seysenegg (1871–1962).

Although interest in genetics grew rapidly after 1900, a fundamental problem remained. Geneticists based all of their laws, theories, and experiments on the concept of the gene. But no one had any idea as to what was a gene. It seemed clear that the gene was probably some kind of chemical compound, or some combination of compounds. But no one had been able to determine exactly what kind of compound or compounds it was.

The answer to that question came in 1953. The American biologist James Watson (1928– ) and the English chemist Francis Crick (1916– ) collaborated to discover that a gene was a section of a very large and complex molecule found in the nuclei of all cells, the deoxyribonucleic acid (DNA) molecule.

The Chemistry of Genes

Imagine a very long chain of beads strung together to form a strand containing hundreds of thousands of beads. The strand contains beads of only four colors: red, yellow, blue, and green. That strand of beads can be compared to half of a DNA molecule. The other half of the molecule is a second strand almost identical to the first strand.

Watson and Crick showed that the sequence in which various colors of beads occur is significant. A DNA molecule in which the beads are arranged in the sequence blue-yellow-yellow-red-red-blue-blue-blue-, and so on, has meaning for a cell. The sequence tells the “chemical machinery” of the cell to make a certain kind of protein, such as the protein responsible for red hair or blue eyes. Another sequence of colors, for example, red-red-yellow-green-blue-green-red-, and so on, might be the “code” for making blonde hair or green eyes.

The components of a DNA molecule are not, of course, colored beads. They are certain groups of atoms known as nucleotides. Each nucleotide in a DNA molecule is comparable to one of the colored beads in the analogy above. Just as there are only four colors of beads in the above analogy, so there are only four different nucleotides in DNA molecules. Those nucleotides might be represented by the symbols A, C, G, and T (corresponding to bead colors of red, blue, green, and yellow). A DNA molecule, then, is a very long chain of nucleotides with a structure something like the following:

-C-T-A-T-C-G-A-C-T-T-G-A-C-T-T-T-G-C-C-A-C-A-A-C- …

The dots at the end of the chain indicate that the chain actually goes on much, much longer.

Watson and Crick said that each set of three nucleotides—they called them triads or codons—carried a specific message that cells could understand. Those messages told a cell to “make red hair,” or “make blue eyes,” or “help a person to grow tall,” or “give a person musical talent,” or any one of thousands of other traits that each human possesses.

This discovery answered the first question that geneticists had about heredity: how cells know which traits they are “supposed” to make and what functions they are “supposed” to carry out. The same discovery also answered the second question puzzling geneticists: how do these traits get passed down from generation to generation?

The answer to that question is that DNA molecules have the ability to make copies of themselves. When a cell divides (reproduces), so do the DNA molecules it contains. In most cases, two exactly identical molecules are produced from a single parent molecule.

When an egg cell (female reproductive cell) and a sperm cell (male reproductive cell) unite during fertilization, each cell provides DNA to the fertilized egg. The DNA from both parents combines to form DNA for the offspring. Whatever nucleotide sequences the mother and father had in their own cells, they pass on to their child.

Dominant and Recessive Traits

One fundamental question remains in the above example: suppose that a child is born to a father with red hair and a mother with blonde hair. What color hair will the child have?

Mendel worked with this question long before Watson and Crick discovered the nature of DNA. He found that for any one genetic trait, there were always two possible conditions. A flower might be red or white; a plant might be tall or short; a pea pod might be smooth or wrinkled; and so on. Mendel also discovered that one of these two conditions was more likely to “win out” over the other. He called the “winner” the dominant trait and the loser the recessive trait.

If a pea plant inherits a “tall” gene for height from both parent plants, the offspring is most like to be tall. If the pea plants inherits a “short” gene for height from both parent plants, the offspring is most likely to be short. But if the pea plant inherits a “tall” gene from one parent and a “short” gene from the second parent, the offspring is most likely to be tall.

An important part of Mendel’s work was finding out what the mathematical chances of various kinds of combinations might be. For example, he showed how to calculate the probabilities that would result when a “tall” parent pea plant was crossed with a “short” parent pea plant in the first, second, and succeeding generations.

The Future of Genetics

One can apply the principles of genetics in a great many situations without knowing anything about the structure of DNA molecules. However, the Watson-Crick discovery made possible a revolutionary change in the basic nature of genetics. As long as scientists had no idea as to what a gene was, there was not much they could do to make changes in the genes of a plant, animal, or human. But Watson and Crick showed that genes are nothing other than chemical compounds. If someone can make changes in chemical compounds in a laboratory, that person can also make changes in a DNA molecule. The problems faced are a good deal more difficult since DNA molecules are far more complex than most molecules that chemists work with. But the basic principles involved are the same.

Scientists are exploring a variety of ways in which genes can be modified to produce cells that can do things they could not do before. For example, it is possible to create the gene for the hormone (chemical messenger) known as insulin in a chemical laboratory. The work is fairly difficult, but by no means impossible. It simply requires that the correct atoms be assembled in the correct sequence. That artificial gene can then be inserted into the DNA of other organisms, such as bacteria. When the artificial gene becomes part of the bacterial DNA, it begins to function just like all the other genes in the bacteria’s DNA. The bacteria begins to function as an “insulin factory,” making a vitally important compound that it could never make before.

One of the most exciting recent developments in genetics is the initiation of the Human Genome Project, which officially began on October 1, 1990. This project is designed to provide a complete genetic road map outlining the location and function of the approximately 50,000 genes in human deoxyribonucleic acid (DNA) and to determine the sequences of the 3,000,000,000 base pairs that make up human DNA. As a result, genetic researchers will have easy access to specific genes to study how the human body works and to develop therapies for diseases. Gene maps for other species of animals also are being developed.

There appears to be virtually no technical limit to the things that scientists can do with genes. But with the promise of genetic research, many ethical and philosophical questions arise. One question is, of course, whether there are social or ethical limits to the kinds of changes scientists ought to be allowed to make in the genes of plants, animals, and humans. With research focusing on the ability to manipulate genes, there is the fear that the results will not always be beneficial. For the most part, the benefits for medicine and agriculture seem to far outweigh the possible abuses, and genetic research continues.

Back to Science Research Paper Topics .

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Special Issue “Latest Review Papers in Molecular Genetics and Genomics 2023”

Apostolos zaravinos.

1 Department of Life Sciences, School of Sciences, European University Cyprus, 2404 Nicosia, Cyprus; [email protected]

2 Cancer Genetics, Genomics and Systems Biology Laboratory, Basic and Translational Cancer Research Center (BTCRC), 2404 Nicosia, Cyprus

In the rapidly evolving landscape of molecular genetics and genomics, this Special Issue brings together a collection of insightful review articles that delve into the forefront of scientific exploration.

The Special Issue titled “Latest Advances in Molecular Genetics and Genomics (2023)” of the International Journal of Molecular Sciences includes nine reviews underscoring the remarkable strides made in our understanding of fundamental biological processes and their implications for human health and disease. Spanning diverse topics, the nine articles presented herein illuminate various facets of molecular genetics and genomics, shedding light on the intricate interplay of genetic information, cellular pathways, and disease mechanisms.

A pivotal theme that emerges from these articles is the burgeoning role of non-coding RNAs in shaping gene expression and cellular function. The intricate regulatory networks orchestrated by microRNAs (miRNAs) and circular RNAs (circRNAs) have garnered significant attention as they control gene expression at the transcriptional and post-transcriptional levels and, thus, play a critical role in tumorigenesis and cancer progression. The work by Kim et al. [ 1 ] reveals the intricate circular RNA–microRNA axis in cancer, where these non-coding RNAs engage in a complex interplay, influencing tumorigenesis and progression across multiple cancer types. The authors focus on the biological regulation of the correlative axis among circular RNAs, miRNAs, and their target genes in various cancer types and suggest the biological importance of miRNAs derived from transposable elements (MDTEs) interacting with oncogenic or tumor-suppressive circRNAs in tumor progression [ 1 ].

Similarly, the study by Pierzynowska et al. [ 2 ] underscores the multifaceted involvement of the oxytocin receptor (OXTR) and its ligand in various diseases, highlighting the delicate balance between behavior, molecular signaling, and pathogenesis. The authors summarize the involvement of OXTR dysfunctions and polymorphisms in the development of different diseases, including cancer, cardiac disorders, osteoporosis, and obesity. Their analysis suggests that changes in OXTR expression and OXTR abundance and activity are not specific to individual diseases but rather influence processes that might modulate the course of various disorders. The authors also propose a possible explanation of the discrepancies in the published results of the effects of the OXTR gene polymorphisms and methylation on different diseases [ 2 ].

Advances in technology have also enabled comprehensive exploration of genetic alterations and their clinical implications. The investigation by Aveta et al. [ 3 ] comprehensively surveys urinary microRNAs (umiRNAs) as potential biomarkers for urological cancers. This systematic review offers insights into the diagnostic and prognostic potential of umiRNAs, illuminating new avenues for non-invasive cancer detection and monitoring. Their systematic review suggests that umiRNAs could play an important role in the diagnosis, prognosis, and therapy of urological cancers [ 3 ].

Additionally, the study by Moeckel et al. [ 4 ] delves into the promise of tumor mutation burden (TMB) as a predictive biomarker for immune checkpoint inhibitor response. The authors discuss the cellular composition in the tumor microenvironment (TME) and the variability in gene mutations across different tumors. They also describe the association between mutations and the response of the immune system, as well as how TMB can be used as a potential biomarker to predict such a response to immune checkpoint inhibitors (ICI). The intricacies of TMB in different cancer types are meticulously examined, emphasizing the need for personalized approaches to harness its predictive power effectively and overcome immunoresistance to ICI therapies. The authors further highlight new trends in the field, such as liquid biopsies, next-generation sequencing, chimeric antigen receptor T-cell therapy, and personalized tumor vaccines [ 4 ].

The integration of genomics and molecular mechanisms is underscored by investigations into gene architecture and regulation. Kyrchanova et al. [ 5 ] provide a detailed exploration of enhancer–promoter interactions in Drosophila, revealing insights into the orchestration of long-range gene regulation. Their work describes the current progress in the interactions at three well-studied key regulatory loci in Drosophila [ 5 ]. Specifically, they describe the different models that have been used to decipher the distance interactions between regulatory elements, as well as the current models of communication between enhancers and promoters. In addition, the authors discuss the role of the interacting insulators from an autonomous regulatory domain of the eve gene in Drosophila. They further explain how insulators and tethering elements provide independent regulation of genes in the antennapedia gene complex, as well as how boundaries organize the enhancer–promoter interactions in the Abd-B gene of the bithorax complex in Drosophila [ 5 ].

Meanwhile, Franzago et al. [ 6 ] shed light on the emerging field of chrono-nutrition (i.e., the study of the impact of the timing of eating by matching elements from nutritional research with chrono-biology), where the intersection of circadian rhythms and personalized nutrition holds promise for mitigating chronic diseases through tailored dietary strategies. Overall, this review provides an overview of the current evidence on the interactions between the circadian system and nutrition, highlighting how this link could, in turn, influence the epigenome and microbiome. In addition, the authors suggest possible nutritional strategies to manage circadian-aligned feeding [ 6 ].

Other articles in this Special Issue delve into the significance of germline and somatic alterations in key genes like MRE11, RAD50, and NBN and offer mechanistic insights into IQSEC2 disease and the use of Schmidtea mediterranea as a model organism for studying human motile ciliopathies.

Specifically, Otahalova et al. [ 7 ] outline the structural characteristics of the MRE11, RAD50, and NBN proteins and the assembly and functions of the MRN complex from the perspective of clinical interpretation of germline and somatic alterations in the MRE11, RAD50, and NBN genes. They describe the structure of the MRN Complex and its function in double-strand break (DSB) repair and analyze the different germline alterations of the MRN complex genes in autosomal recessive syndromes, as well as the association between heterozygous germline alterations in these genes and cancer predisposition. Their review finally explores the role of somatic alterations in the MRN complex genes in different tumors [ 7 ].

Furthermore, the review by Levy et al. [ 8 ] outlines recent insights into IQSEC2 disease (an X-linked disorder associated with intellectual disability, autism, and epilepsy), including the identification of missense mutations in functional domains through patient DNA sequencing, recapitulation of autistic-like behavior, and seizures in transgenic mouse models. The review highlights the role of IQSEC2 in neurotransmission and neuronal development, the constitutively high levels of Arf6-GTP in knockout mice, and the potential therapeutic benefit of heat treatment for the IQSEC2 A350V mutation [ 8 ].

Lastly, Rabiasz et al. [ 9 ] discuss the ultrastructure of motile cilia and review the use of this simple and accessible planarian model for studying the genetics of primary ciliary dyskinesia (PCD) and other cilia-related diseases.

As we reflect on these diverse contributions in the Special Issue “Latest Advances in Molecular Genetics and Genomics (2023)”, a common thread emerges: the intricate link between genetics, molecular mechanisms, and disease. These review papers collectively underscore the remarkable strides we have taken in unraveling the molecular complexities of different diseases while also highlighting the tantalizing prospects that lie ahead.

Overall, the studies in this Special Issue highlight the latest developments in molecular genetics and genomics and improve our current understanding of key mechanisms involved in this field. These findings not only showcase the accomplishments of the past but also pave the way for exciting avenues of further investigation in the field of molecular genetics and genomics.

In closing, I would like to extend my deepest gratitude to the authors, reviewers, and Editorial team for their invaluable contributions to this Special Issue. I hope that these articles will not only enhance our understanding of molecular genetics and genomics but also inspire further inquiry and innovation in this dynamic and ever-evolving field.

Conflicts of Interest

The authors declares no conflict of interest.

Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

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The Basics Of Choosing Genetic Research Paper Topics

Table of Contents

Genetics is an academic discipline that studies the genes and heredity in living organisms. The study of genetics takes place in many universities in the world today. Over the years, we’ve reached unprecedented levels of knowledge in genetics. From the discovery of DNA structure to gene sequencing that is behind human life, tremendous progress has been achieved.

The role of genetics is so great today that it influences almost all aspects of our lives, including medicine, pharmaceuticals, and ethics. Over the past half century, knowledge of genetics has grown significantly. It’s been a long journey from the discovery of DNA and up to the sequence of genes. Therefore, writing a decent research paper on genetics is quite an adventure today.

Note that choosing the right topic will reduce the difficulty of writing your research. Also, make sure that the topic has sufficient reliable resources before you start writing.

Let’s go!

Specifics of choosing a topic for a research paper in genetics

Thinking of a topic, keep in mind the rationale for studying genetics. It must consider a combination of basic concepts of genes, gene expression, and DNA structure. A great topic will also incorporate methods used in genetic analysis and touch on the social and political impacts of genetics.

A well-chosen topic leaves the reader with an in-depth understanding of a specified aspect of genetics, communicating complex scientific information and explaining it to a reader.

Choosing the right topic will also reduce the difficulty of writing a good research paper by ensuring that the topic has enough credible resources to research.

List of popular genetics topics

With any of the topic we list below, you will be able to write a good research paper on genetics.

Remember that a topic choice can make or break your research paper.

Choosing a topic of your genuine interest means joyful writing process and coming up with high-quality content.

Interesting genetics research topics

Can dinosaur DNA be recovered?
The possibility of cloning.
Is there a correlation between human behavior and genetics?
Genetics research and the environment.
Is there a connection between allergies and human genetics?
Hereditary diseases and genetics.
Genetics: problems and perspectives.
Why don’t we all look alike?
Latest methods of human genetics research.
Genetic fund of the nation.

Genetics topics for research papers

Genetics became quite popular in the 21st century. Loads of projects have led to significant achievements in the health sector by providing the know-how to the medical sector.

Check out examples of topics for your research papers on genetics:

What factors in human genetics affecting behavior?
Is it somehow possible to improve human personality through genetics?
Malaria treatment with the help of gene mutation.
The help of genetic tests in a fight against Alzheimer’s disease.
Genetics and its role in cancer studies.
Can genetic code be confidential?
Is it possible to choose the sex of a person before birth?
Genetics as a ray of hope for children who have an intellectual disability.
Are there any living cells in the gene?
Fighting HIV with gene mutations.

Genetics topics for presentation

Need some topics for a stunning presentation, that would cut through like a lightning strike?

Try out one of those:

Replacement of genes and artificial chromosomes.
Gene mutations.
Human genetics.
Genetics and its impact on human diseases.
Germ Immunization.
Genetics and Parkinson’s disease.
Creation of transgenic organisms.
People cloning.
Genetic analysis of DNA structure.

Most controversial genetics topics

With the new genetic and diagnostic achievements, there is a lot of controversy about how they should be implemented. For example, there are concerns that genetic information may be used to discriminate particular groups of people (like, in cases of health insurance refusal, etc.).

Controversial issues also include the issue of human genetic information confidentiality and whether genetic testing should be mandatory.

Also, various disputes arise from religious beliefs, ethics, and so on. We pay close attention to examples of controversial topics in genetics:

Cloning: positive or negative outcome for future generations?
Do companies have the right to patent human genes?
Genetic testing: is it necessary?
Is it ethical to grow human organs?
Is it legal for parents to order genetically perfect children?
Artificial insemination vs. ordinary pregnancy.
How accurate can a genetic test be?
Growing up a perfect person or playing God?
Are we ready for bioethics revolution?
Who owns the right to the human genome?

What are the hottest topics in genetics?

The latest research states that most discussed topics in the genetic field are the following ones:

Blood group.
Genes mutation.
Human Genome Project.
Nucleotide.
Nucleic acids.
What is the gene?
RNA Information.

Challenging genetics paper topics

Are you into difficult tasks and challenges? Coll! We’ve got several ideas for you!

Pros and cons of genetic engineering.
Advantages of human genetic engineering.
Genetic databases.
Does genetics have an impact on homosexuality?
Genetics and obesity.
Genetics and Autism.
Genetics and Schizophrenia.
Pros and cons of GMO.
Genetic diagnosis of the fetus.
Genetics and cancer.

Today’s genetics studies still have more questions than answers. A rightly chosen topic for your paper won’t only result in a good grade, but also make an exceptional contribution to science.

No time to write your top-notch genetics research paper? Here’s an idea! Choose any topic from our list and hand it to a professional writer. Zero plagiarism, complete confidentiality, and on-time delivery guarantee!

Structuring of an argumentative essay on euthanasia

Complete guide on college papers format, how to write assignment in style requested by the professor.

Research Topics

The Center for Genetic Medicine’s faculty members represent 33 departments or programs across three Northwestern University schools and three Feinberg-affiliated healthcare institutions. Faculty use genetics and molecular genetic approaches to understand biological processes for a diverse range of practical and clinical applications.

Select a topic below to learn more and see a list of faculty associated with that type of research. For a full list of Center for Genetic Medicine members, visit our Members section .

Animal Models of Human Disease

Using genetic approaches with model organisms to investigate cellular and physiological processes can lead to improved approaches for detection, prevention and treatment of human diseases.

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Bioinformatics & Statistics

Bioinformatics, a discipline that unites biology, computer science, statistical methods, and information technology, helps researchers understand how genes or parts of genes relate to other genes, and how genes interact to form networks. These studies provide insight to normal cellular functions and how these functions are disturbed by disease. Statistics is central to genetic approaches, providing quantitative support for biological observations, and statistical genetics is heavily used by laboratories performing gene and trait mapping, sequencing and genotyping, epidemiology, population genetics and risk analysis.

Cancer Genetics and Genomics

Cancer begins with genetic changes, or mutations, that disrupt normal regulation of cell proliferation, survival and death. Inherited genetic changes contribute to the most common cancers, like breast and colon cancer, and genetic testing can help identify risks for disease. Tumors also develop additional genetic changes, or somatic mutations, that promote cancer growth and tumor metastases. These genetic changes can be readily defined through DNA and RNA sequencing. Genetic changes within a tumor can be used to develop and guide treatment options.

Cardiovascular Genetics

Cardiovascular disease is one of the leading causes of death in the US, and the risk of cardiovascular disease is highly dependent inherited genetic changes. The most common forms of heart disease including heart failure, arrhythmias, and vascular disease are under heritable genetic changes. We work to identify and understand the functions of genes that affect the risk of developing cardiovascular disease, as well as to understand the function of genes involved in the normal and pathological development of the heart.

Clinical and Therapeutics

Using genetic data identifies pathways for developing new therapies and applying existing therapies. DNA sequencing and epigenetic profiling of tumors helps define the precise defects responsible for cancer progression. We use genetic signals to validate pathways for therapy development. We are using gene editing methods to correct genetic defects. These novel strategies are used to treat patients at Northwestern Memorial Hospital and the Ann & Robert H. Lurie Children's Hospital of Chicago.

Development

The genomic blueprint of a single fertilized egg directs the formation of the entire organism. To understand the cellular processes that allow cells to create organs and whole animals from this blueprint, we use genetic approaches to investigate the development of model organisms and humans. Induced pluripotent stem cells can be readily generated from skin, blood or urine cells and used to mirror human developmental processes. These studies help us define how genes coordinate normal human development and the changes that occur in diseases, with the goal of improving detection, prevention and treatment of human disease.

Epigenetics/Chromatin Structure/Gene Expression

Abnormal gene expression underlies many diseases, including cancer and cardiovascular diseases. We investigate how gene expression is regulated by chromatin structure and other regulators to understand abnormal gene expression in disease, and to learn how to manipulate gene expression for therapeutic purposes.

Gene Editing/Gene Therapy

Gene editing tools like CRISPR/Cas can be used to directly alter the DNA code. This tool is being used to generate cell and animal models of human diseases and disease processes. Gene therapy is being used to treat human disease conditions.

Genetic Counseling

As part of training in genetic counseling, each student completes a thesis project. These projects examine all aspects of genetic counseling ranging from family-based studies to mechanisms of genetic action. With the expansion of genetic testing, genetic counselors are now conducting research on outcomes, cost effectiveness, and quality improvement.

Genetic Determinants of Cellular Biology

Genetic mutations ultimately change the functionality of the cells in which they are found. Mutations in genes encoding nuclear, cytoplasmic and extracellular matrix protein lead to many different human diseases, ranging from neurological and developmental disorders to cancer and heart disease. Using induced pluripotent stem cell and gene-editing technologies, it is now possible to generate and study nearly every human genetic disorder. Having cellular models of disease is necessary to develop new treatments.

Immunology

Many immunological diseases, such as Rheumatoid arthritis, Lupus, scleroderma, and others have a genetic basis. We work to understand how genetic changes and misregulation contribute to immunological diseases, and use genetic approaches to investigate how the immune system functions.

Infectious Disease/Microbiome

The susceptibility and/or pathological consequences of many infectious diseases have a genetic basis. We investigate how human genes interact with infectious diseases, and use genetic approaches to determine the interactions between pathogens and the host. Genetic tools, including deep sequencing, are most commonly used to define the microbiome as it undergoes adaptation and maladaptation to its host environment.

Neuroscience

We work to understand how genes contribute to neurological diseases, and use genetic approaches to investigate how the nervous system functions. Epilepsy, movement disorders, and dementia are heritable and under genetic influence. Neuromuscular diseases including muscular dystrophies and myopathies arise from primary mutations and research in genetic correction is moving into human trials and drug approvals.

Population Genetics/Epidemiology

Genetic data is increasingly available from large human populations and is advancing the population-level understanding of genetic risk. Northwestern participates in All-Of-US, which aims to build a cohort of one million citizens to expand genetic knowledge of human diseases. Race and ancestry have genetic determinants and genetic polymorphisms can help mark disease risks better than other markers of race/ancestry. We use epidemiology and population genetics to investigate the genetic basis of disease, and to assess how genetic diseases affect subgroups within broader populations.

Reproduction

Research is examining how germ cells are specified. We study the broad range of biology required to transmit genetic information from one generation to another, and how to facilitate the process of reproduction when difficulties arise or to avoid passing on mutant genes.

Follow Center for Genetic Medicine on Twitter

132 Genetic Engineering Essay Topic Ideas & Examples

Welcome to our list of genetic engineering essay topics! Here, you will find everything from trending research titles to the most interesting genetic engineering topics for presentation. Get inspired with our writing ideas and bonus samples!

🔝 Top 10 Genetic Engineering Topics for 2024

🏆 best genetic engineering topic ideas & essay examples, ⭐ good genetic engineering research topics, 👍 simple & easy genetic engineering essay topics, ❓ genetic engineering discussion questions, 🔎 genetic engineering research topics, ✅ genetic engineering project ideas.

Ethical Issues of Synthetic Biology
CRISPR-Cas9 and Its Applications
Progress and Challenges in Gene Therapy
Applications of Gene Editing in Animals
The Process of Genetic Engineering in Plants
Genetic Engineering for Human Enhancement
Genetic Engineering for Improving Crop Yield
Regulatory Issues of Genetic Editing of Embryos
Gene Silencing in Humans through RNA Interference
Gene Drive Technology for Controlling Invasive Species
Future of Genetic Engineering and the Concept of “Franken-Foods” This is not limited to cows alone but extends to pigs, sheep, and poultry, the justification for the development of genetically modified food is based on the need to feed an ever growing population which […]
The Ethical Issues of Genetic Engineering Many people have questioned the health risks that arise from genetically modified crops, thus it is the politicians who have to ensure that the interests of the people are met and their safety is assured. […]
Gattaca: Ethical Issues of Genetic Engineering Although the world he lives in has determined that the only measure of a man is his genetic profile, Vincent discovers another element of man that science and society have forgotten.
The Film “Gattaca” and Genetic Engineering In the film, it is convincing that in the near future, science and technology at the back of genetic engineering shall be developed up to the level which makes the film a reality.
The Dangers of Genetic Engineering and the Issue of Human Genes’ Modification In this case, the ethics of human cloning and human genes’ alteration are at the center of the most heated debates. The first reason to oppose the idea of manipulation of human genes lies in […]
Changing the world: Genetic Engineering Effects Genes used in genetic engineering have a high impact on health and disease, therefore the inclusion of the genetic process alters the genes that influence human behavior and traits.
Human Genetic Engineering: Key Principles and Issues There are many options for the development of events in the field of genetic engineering, and not all of them have been studied. To conclude, human genetic engineering is one of the major medical breakthroughs, […]
Mitochondrial Diseases Treatment Through Genetic Engineering Any disorders and abnormalities in the development of mitochondrial genetic information can lead to the dysfunction of these organelles, which in turn affects the efficiency of intracellular ATP production during the process of cellular respiration.
Genetic Engineering: Is It Ethical to Manipulate Life? In the case of more complex operations, genetic engineering can edit existing genes to turn on or off the synthesis of a particular protein in the organism from which the gene was taken.
Biotechnology and Genetic Engineering Apart from that, there are some experiments that cannot be ethically justified, at least in my opinion, for example, the cloning of human being or the attempts to find the gene for genius.
Genetic Engineering in the Movie “Gattaca” by Niccol This would not be right at all since a person should be responsible for their own life and not have it dictated to them as a result of a societal construct created on the basis […]
Religious vs Scientific Views on Genetic Engineering With the need to increase the global economy, the field of agriculture is one among the many that have been used to improve the commercial production to take care of the global needs for food […]
Genetic Engineering Using a Pglo Plasmid The objective of this experiment is to understand the process and importance of the genetic transformation of bacteria in real time with the aid of extrachromosomal DNA, alternatively referred to as plasmids.
Managing Diabetes Through Genetic Engineering Genetic engineering refers to the alteration of genetic make-up of an organism through the use of techniques to introduce a new DNA or eliminate a given hereditable material. What is the role of genetic engineering […]
The Role of Plant Genetic Engineering in Global Security Although it can be conveniently stated that the adequacy, abundance and reliability of the global food supply has a major role to play in the enhancement of human life, in the long run, they influence […]
Significance of Human Genetic Engineering The gene alteration strategy enables replacing the specific unwanted genes with the new ones, which are more resistant and freer of the particular ailment, hence an essential assurance of a healthy generation in the future.
Is the World Ready for Genetic Engineering? The process of manipulating genes has brought scientists to important discoveries, among which is the technology of the production of new kinds of crops and plants with selected characteristics. The problem of the advantages and […]
Genome: Bioethics and Genetic Engineering Additionally, towards the end of the documentary, the narrator and some of the interviewed individuals explain the problem of anonymity that is also related to genetic manipulations.
Is Genetic Engineering an Environmentally Sound Way to Increase Food Production? According to Thomas & Earl and Barry, genetic engineering is environmentally unsound method of increasing food production because it threatens the indigenous species.
A Major Milestone in the Field of Science and Technology: Should Genetic Engineering Be Allowed? The most controversial and complicated aspect of this expertise is Human Genetic Engineering- whereby the genotype of a fetus can be altered to produce desired results.
Genetic Engineering Is Ethically Unacceptable However, the current application of genetic engineering is in the field of medicine particularly to treat various genetic conditions. However, this method of treatment has various consequences to the individual and the society in general.
Designer Genes: Different Types and Use of Genetic Engineering McKibben speaks of Somatic Gene Therapy as it is used to modify the gene and cell structure of human beings so that the cells are able to produce certain chemicals that would help the body […]
A Technique for Controlling Plant Characteristics: Genetic Engineering in the Agriculture A cautious investigation of genetic engineering is required to make sure it is safe for humans and the environment. The benefit credited to genetic manipulation is influenced through the utilization of herbicide-tolerant and pest-safe traits.
Genetically Engineered Food Against World Hunger I support the production of GMFs in large quality; I hold the opinion that they can offer a lasting solution to food problems facing the world.
Genetic Engineering in Food: Development and Risks Genetic engineering refers to the manipulation of the gene composition of organisms, to come up with organisms, which have different characteristics from the organic ones.
Genetic Engineering in the Workplace The main purpose of the paper is to evaluate and critically discuss the ethical concerns regarding the implementation of genetic testing in the workplace and to provide potential resolutions to the dilemmas.
Designer Babies Creation in Genetic Engineering The creation of designer babies is an outcome of advancements in technology hence the debate should be on the extent to which technology can be applied in changing the way human beings live and the […]
Genetic Engineering and Eugenics Comparison The main idea in genetic engineering is to manipulate the genetic make-up of human beings in order to shackle their inferior traits. The concept of socially independent reproduction is replicated in both eugenics and genetic […]
Ecological Effects of the Release of Genetically Engineered Organisms Beneficial soil organisms such as earthworms, mites, nematodes, woodlice among others are some of the soil living organisms that are adversely affected by introduction of genetically engineered organisms in the ecosystem since they introduce toxins […]
Proposition 37 and Genetically Engineered Foods The discussion of Proposition 37 by the public is based on the obvious gap between the “law on the books” and the “law in action” because Food Safety Law which is associated with the Proposition […]
Is Genetically Engineered Food the Solution to the World’s Hunger Problems? However, the acceptance of GMO’s as the solution to the world’s food problem is not unanimously and there is still a multitude of opposition and suspicion of their use.
Benefits of Genetic Engineering as a Huge Part of People’s Lives Genetic Engineering is said to question whether man has the right to manipulate the course and laws of nature and thus is in constant collision with religion and the beliefs held by it regarding life.
Perfect Society: The Effects of Human Genetic Engineering
Genetic Engineering and Forensic Criminal Investigations
Biotechnology Assignment and Genetic Engineering
Genetic Engineering and Genetically Modified Organisms
Bio-Ethics and the Controversy of Genetic Engineering
Health and Environmental Risks of Genetic Engineering in Food
Genetic Engineering and the Risks of Enforcing Changes on Organisms
Genetic Engineering and How It Affects Globel Warming
Cloning and Genetic Engineering in the Food Animal Industry
Genetic Engineering and Its Impact on Society
Embryonic Research, Genetic Engineering, & Cloning
Genetic Engineering: Associated Risks and Possibilities
Issues Concerning Genetic Engineering in Food Production
Genetic Engineering, DNA Fingerprinting, Gene Therapy
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Advanced genetic tools help researchers id new neurodevelopmental syndrome.

A child and an image of genetic sequencing

In a recent study, a Yale-led research team described for the first time a rare neurodevelopmental syndrome that begins affecting patients during infancy, and typically causes developmental delays, severe seizures, cardiac dysrhythmia, and recurring infection.

After conducting a genetic analysis on 18 individuals with similar symptoms — but for whom there was no established diagnosis — and comparing the results with other findings, the research team, led by Yale’s Saquib Lakhani and Lauren Jeffries , was able to discern the genetic roots of what they determined was a syndrome shared by all of the patients.

According to their findings, published in the journal Genetics in Medicine, the newly defined syndrome — now known as Jeffries-Lakhani Neurodevelopment Syndrome, or JELANS — arises when patients have variants in a gene called CRELD1 , which has known roles in the cardiac and immune systems but had never before been characterized in patients with neurodevelopmental symptoms.

The discovery would not have been possible, researchers say, without next-generation DNA sequencing, a tool refined within the past decade that can rapidly sequence thousands of genes or even entire genomes.

“ The advancements in DNA sequencing have completely transformed how we approach patients,” said Lakhani , clinical director of Yale School of Medicine’s Pediatric Genomics Discovery Program and senior author of the study.

With next-generation sequencing, researchers can uncover alterations in genes — also known as variants — shared by people around the world with similar symptoms. That allows them to draw connections that may have been missed when relying on symptoms alone.

In this case, and in a growing number of others, it means a disorder that had gone undiscovered is now named and defined, giving those affected by it much-needed answers and researchers a clearer route to treatment development.

Lakhani and Jeffries, an associate research scientist and medical geneticist with the Pediatric Genomics Discovery Program and lead author of the study, recently sat down with Yale News to discuss JELANS and the process of identifying a new syndrome, how the program’s “gene-centric” approach to care yielded this discovery, and how it benefits families facing these rare disorders.

This interview has been edited and condensed.

This study included numerous individuals experiencing similar symptoms. Why did you suspect that this group of symptoms might in fact be a previously unknown syndrome?

Lauren Jeffries: It may be surprising to know that, even in 2024, while over 7,000 rare genetic disorders are already defined, the majority of our 20,000 genes are still not well understood. So, while comparing clinical notes across patients is still critical to our work, in the Pediatric Genomics Discovery Program we utilize a “gene-centric” approach, meaning that instead of comparing symptoms, we look for genetic differences as our first step.

In this particular case, GeneDx — a commercial lab headquartered in Connecticut that we collaborate with — had genetically screened 10 patients who had compound heterozygous variants for the CRELD1 gene. That means that the patients had two variants in this gene, one coming from their mom and one from their dad. GeneDx then asked if we wanted to look into this further. Most of the patients in our full cohort ended up sharing the exact same change, which was remarkably suspicious.

What is needed to identify a novel syndrome?

Saquib Lakhani: In general, you need a certain number of patients and consistency in the characteristics of those patients. You also typically need basic science evidence — which could be biochemical, cell system, or animal model testing — that corroborates that the variation in the gene in question is associated with the condition in the patients you’ve identified, and that it causes some changes or abnormalities in the scientific testing. And ultimately you need to be able to get a paper describing the syndrome published, indicating that your peers have accepted the evidence defining the syndrome.

How were you able to determine the characteristics of JELANS?

Jeffries: We worked with an incredible team of researchers to find 18 patients from 14 families in the U.S., Canada, and the U.K., including one who we cared for in our pediatric ICU here at Yale. When no established diagnoses were identified for them, their genetic data was analyzed under the research lens. From this deeper analysis of genetic data, the CRELD1 gene emerged as the candidate to study.

We also looked through their clinical data to see what patterns might exist. All of the patients had low muscle tone at birth. In the majority of cases, epilepsy developed by around five months of age, and all patients had seizures at some point in time. Cardiac dysrhythmias and recurrent infections were also common, and we noticed that several patients had shared facial features such as large-appearing eyes.

Lakhani: We then studied the gene in frogs. We first wanted to see what happened when we removed the gene, because that can give us a clue as to what the gene is important for. When we fully knocked out the gene, the frog embryos did not survive. But when the gene was partially knocked out, we found that there were a lot of developmental defects in these frogs. Interestingly, surviving tadpoles with the gene significantly knocked out were more susceptible to developing seizures. That showed us that CRELD1 is important for the development of the embryo overall and that if it’s limited in function, it can also increase the susceptibility to seizures.

However, these patients aren’t missing CRELD1 , they have variations in it: letter changes in the gene that result in changes to the CRELD1 protein but do not cause the protein to completely disappear. When we tested the patient forms of the protein in tadpoles, we found that they did not function the same way as the normal form of CRELD1. Taken together, the clinical and basic science data provides solid evidence that JELANS is a new syndrome caused by variants in the CRELD1 gene.

Is there additional research needed on this syndrome?

Jeffries: As more patients are identified to have JELANS, I think we’ll further refine the clinical syndrome and begin to uncover the molecular mechanisms underlying the symptoms. For instance, we’ll get a better sense of whether the immune system is affected, leading to the increased risk of infection, and how common cardiac dysrhythmias are and what’s the underlying cause.

Why is it important to describe and name a syndrome beyond simply treating the symptoms?

Lakhani: The families of children with undiagnosed diseases frequently go through wandering medical diagnostic odysseys — doctor after doctor, test after test — without ever reaching an answer. Parents can go their entire lives wondering what happened to their child, whether their other children can get the disease, whether they did something to cause it. Knowing a syndrome name and the underlying genetic cause can be so powerful by bringing a sense of closure and relief to families.

Jeffries: It’s validating. It’s clarifying. With a syndrome name, families can find a community and move forward. Especially for rare disorders, in syndrome support groups families can share their stories, discuss what treatments have worked and what treatments haven’t, and just talk to other parents who understand.

Lakhani: And in some countries, it can be hard to get resources without a specific diagnosis. With a diagnosis, families may qualify for support services, so it can have practical implications even beyond the knowledge.

In this case, how will the discovery inform treatment?

Jeffries: Understanding this syndrome at the molecular level is essential for the ultimate goal of finding treatment that’s targeted and specific to this disorder and that is meaningful in helping patients thrive.

Is this an approach others can use?

Lakhani: Everyone who cares for patients should be thinking about this. For many years, as physicians we would look at certain patients and say, “They’ve got something underlying.” But we could never put our finger on it because we didn’t have a robust way to test broadly for genetic conditions; we had to just do the best we could. But we now have a tool that allows us to see if there’s a genetic explanation for a child’s condition. We no longer have to just do the best we can with limited information. We can actually try to find answers. It’s something that has had an incredible impact and it’s something we regularly encourage others to pursue.

Jeffries: And while the discovery of JELANS was through a research endeavor, we want to be clear that DNA sequencing is not just for uncovering new syndromes. Genetic testing can be ordered by a doctor and is available for patients with all sorts of descriptive diagnoses, such as autism, intellectual disability, epilepsy, and cerebral palsy, where symptoms determine the diagnosis.

A patient’s genes may reveal a more specific diagnosis than any constellation of symptoms can define; understanding the molecular cause can ultimately give patients clearer answers and, hopefully, more targeted treatments.

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CHARMed collaboration creates a potent therapy candidate for fatal prion diseases

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Drug development is typically slow: The pipeline from basic research discoveries that provide the basis for a new drug to clinical trials and then production of a widely available medicine can take decades. But decades can feel impossibly far off to someone who currently has a fatal disease. Broad Institute of MIT and Harvard Senior Group Leader Sonia Vallabh is acutely aware of that race against time, because the topic of her research is a neurodegenerative and ultimately fatal disease — fatal familial insomnia, a type of prion disease — that she will almost certainly develop as she ages.

Vallabh and her husband, Eric Minikel, switched careers and became researchers after they learned that Vallabh carries a disease-causing version of the prion protein gene and that there is no effective therapy for fatal prion diseases. The two now run a lab at the Broad Institute, where they are working to develop drugs that can prevent and treat these diseases, and their deadline for success is not based on grant cycles or academic expectations but on the ticking time bomb in Vallabh’s genetic code.

That is why Vallabh was excited to discover, when she entered into a collaboration with Whitehead Institute for Biomedical Research member Jonathan Weissman, that Weissman’s group likes to work at full throttle. In less than two years, Weissman, Vallabh, and their collaborators have developed a set of molecular tools called CHARMs that can turn off disease-causing genes such as the prion protein gene — as well as, potentially, genes coding for many other proteins implicated in neurodegenerative and other diseases — and they are refining those tools to be good candidates for use in human patients. Although the tools still have many hurdles to pass before the researchers will know if they work as therapeutics, the team is encouraged by the speed with which they have developed the technology thus far.

“The spirit of the collaboration since the beginning has been that there was no waiting on formality,” Vallabh says. “As soon as we realized our mutual excitement to do this, everything was off to the races.”

Co-corresponding authors Weissman and Vallabh and co-first authors Edwin Neumann, a graduate student in Weissman’s lab, and Tessa Bertozzi, a postdoc in Weissman’s lab, describe CHARM — which stands for Coupled Histone tail for Autoinhibition Release of Methyltransferase — in a paper published today in the journal Science .

“With the Whitehead and Broad Institutes right next door to each other, I don’t think there’s any better place than this for a group of motivated people to move quickly and flexibly in the pursuit of academic science and medical technology,” says Weissman, who is also a professor of biology at MIT and a Howard Hughes Medical Institute Investigator. “CHARMs are an elegant solution to the problem of silencing disease genes, and they have the potential to have an important position in the future of genetic medicines.”

To treat a genetic disease, target the gene

Prion disease, which leads to swift neurodegeneration and death, is caused by the presence of misshapen versions of the prion protein. These cause a cascade effect in the brain: the faulty prion proteins deform other proteins, and together these proteins not only stop functioning properly but also form toxic aggregates that kill neurons. The most famous type of prion disease, known colloquially as mad cow disease, is infectious, but other forms of prion disease can occur spontaneously or be caused by faulty prion protein genes.

Most conventional drugs work by targeting a protein. CHARMs, however, work further upstream, turning off the gene that codes for the faulty protein so that the protein never gets made in the first place. CHARMs do this by epigenetic editing, in which a chemical tag gets added to DNA in order to turn off or silence a target gene. Unlike gene editing, epigenetic editing does not modify the underlying DNA — the gene itself remains intact. However, like gene editing, epigenetic editing is stable, meaning that a gene switched off by CHARM should remain off. This would mean patients would only have to take CHARM once, as opposed to protein-targeting medications that must be taken regularly as the cells’ protein levels replenish.

Research in animals suggests that the prion protein isn’t necessary in a healthy adult, and that in cases of disease, removing the protein improves or even eliminates disease symptoms. In a person who hasn’t yet developed symptoms, removing the protein should prevent disease altogether. In other words, epigenetic editing could be an effective approach for treating genetic diseases such as inherited prion diseases. The challenge is creating a new type of therapy.

Fortunately, the team had a good template for CHARM: a research tool called CRISPRoff that Weissman’s group previously developed for silencing genes. CRISPRoff uses building blocks from CRISPR gene editing technology, including the guide protein Cas9 that directs the tool to the target gene. CRISPRoff silences the targeted gene by adding methyl groups, chemical tags that prevent the gene from being transcribed, or read into RNA, and so from being expressed as protein. When the researchers tested CRISPRoff’s ability to silence the prion protein gene, they found that it was effective and stable.

Several of its properties, though, prevented CRISPRoff from being a good candidate for a therapy. The researchers’ goal was to create a tool based on CRISPRoff that was just as potent but also safe for use in humans, small enough to deliver to the brain, and designed to minimize the risk of silencing the wrong genes or causing side effects.

From research tool to drug candidate

Led by Neumann and Bertozzi, the researchers began engineering and applying their new epigenome editor. The first problem that they had to tackle was size, because the editor needs to be small enough to be packaged and delivered to specific cells in the body. Delivering genes into the human brain is challenging; many clinical trials have used adeno-associated viruses (AAVs) as gene-delivery vehicles, but these are small and can only contain a small amount of genetic code. CRISPRoff is way too big; the code for Cas9 alone takes up most of the available space.

The Weissman lab researchers decided to replace Cas9 with a much smaller zinc finger protein (ZFP). Like Cas9, ZFPs can serve as guide proteins to direct the tool to a target site in DNA. ZFPs are also common in human cells, meaning they are less likely to trigger an immune response against themselves than the bacterial Cas9.

Next, the researchers had to design the part of the tool that would silence the prion protein gene. At first, they used part of a methyltransferase, a molecule that adds methyl groups to DNA, called DNMT3A. However, in the particular configuration needed for the tool, the molecule was toxic to the cell. The researchers focused on a different solution: Instead of delivering outside DNMT3A as part of the therapy, the tool is able to recruit the cell’s own DNMT3A to the prion protein gene. This freed up precious space inside of the AAV vector and prevented toxicity.

The researchers also needed to activate DNMT3A. In the cell, DNMT3A is usually inactive until it interacts with certain partner molecules. This default inactivity prevents accidental methylation of genes that need to remain turned on. Neumann came up with an ingenious way around this by combining sections of DNMT3A’s partner molecules and connecting these to ZFPs that bring them to the prion protein gene. When the cell’s DNMT3A comes across this combination of parts, it activates, silencing the gene.

“From the perspectives of both toxicity and size, it made sense to recruit the machinery that the cell already has; it was a much simpler, more elegant solution,” Neumann says. “Cells are already using methyltransferases all of the time, and we’re essentially just tricking them into turning off a gene that they would normally leave turned on.”

Testing in mice showed that ZFP-guided CHARMs could eliminate more than 80 percent of the prion protein in the brain, while previous research has shown that as little as 21 percent elimination can improve symptoms.

Once the researchers knew that they had a potent gene silencer, they turned to the problem of off-target effects. The genetic code for a CHARM that gets delivered to a cell will keep producing copies of the CHARM indefinitely. However, after the prion protein gene is switched off, there is no benefit to this, only more time for side effects to develop, so they tweaked the tool so that after it turns off the prion protein gene, it then turns itself off.

Meanwhile, a complementary project from Broad Institute scientist and collaborator Benjamin Deverman’s lab, focused on brain-wide gene delivery and published in Science on May 17, has brought the CHARM technology one step closer to being ready for clinical trials. Although naturally occurring types of AAV have been used for gene therapy in humans before, they do not enter the adult brain efficiently, making it impossible to treat a whole-brain disease like prion disease. Tackling the delivery problem, Deverman’s group has designed an AAV vector that can get into the brain more efficiently by leveraging a pathway that naturally shuttles iron into the brain. Engineered vectors like this one make a therapy like CHARM one step closer to reality.

Thanks to these creative solutions, the researchers now have a highly effective epigenetic editor that is small enough to deliver to the brain, and that appears in cell culture and animal testing to have low toxicity and limited off-target effects.

“It’s been a privilege to be part of this; it’s pretty rare to go from basic research to therapeutic application in such a short amount of time,” Bertozzi says. “I think the key was forming a collaboration that took advantage of the Weissman lab’s tool-building experience, the Vallabh and Minikel lab’s deep knowledge of the disease, and the Deverman lab’s expertise in gene delivery.”

Looking ahead

With the major elements of the CHARM technology solved, the team is now fine-tuning their tool to make it more effective, safer, and easier to produce at scale, as will be necessary for clinical trials. They have already made the tool modular, so that its various pieces can be swapped out and future CHARMs won’t have to be programmed from scratch. CHARMs are also currently being tested as therapeutics in mice.

The path from basic research to clinical trials is a long and winding one, and the researchers know that CHARMs still have a way to go before they might become a viable medical option for people with prion diseases, including Vallabh, or other diseases with similar genetic components. However, with a strong therapy design and promising laboratory results in hand, the researchers have good reason to be hopeful. They continue to work at full throttle, intent on developing their technology so that it can save patients’ lives not someday, but as soon as possible.

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Research Identifies Link Between Genetic Makeup and Disease Risk

Ucla health researchers analyzed a diverse patient population to determine the effect of genes on disease risk, potentially leading to custom treatment..

Mark Melchionna

Using data from the UCLA ATLAS Precision Health Biobank, UCLA Health researchers found differences in diagnoses, hospital use, and genetic disease across various populations, which provided them with a new view ontreatment practices.

According to the Statistic Alatlas, Los Angeles, California, contains a diverse population in terms of ancestry. Although this source indicates that 9.4 percent of the population is unclassified, German, Irish, English, and American are among the most common origins, occupying 4.2 percent, 3.6 percent, 3.0 percent, and 2.9 percent, respectively.

Considering this diversity, UCLA researchers studied the ATLAS Precision Health Biobank. In doing so, they aimed to determine whether disease risks and care access varied across patient populations.

The UCLA ATLAS Precision Health Biobank draws connections between electronic health records and genetic makeup information from biological samples.

While reviewing the large genetic biobank, researchers leveraged information from almost 36,000 enrolled patients. They used a machine-learning algorithm to make connections between groups sharing genetic ancestry. This data allowed them to define 376 population clusters that differed in terms of genetic ancestry.

When comparing patient data across these clusters, researchers noticed dissimilar rates of diagnoses, hospital use, and genetic diseases. Some study results indicated the high level of precision involved in differentiating between ancestry regions.

For example, patients of Mexican and Central American descent varied greatly in terms of health tendencies. After making note of the various subclusters of Mexican patients, researchers noted that only those of the Guatemalan region typically experienced pregnancy complications. Meanwhile, the Central Mexican group was more likely to experience nutritional deficiencies.

Access inconsistencies also emerged from research findings. Those of Iranian Jewish descent, for example, experienced higher rates of adjustment disorder diagnoses, a condition that is rarely accounted for in medical record data. Researchers also found that one medical center provided these diagnoses, which show how social statuses have a high impact on outcomes.

These findings run perpendicular to the typical practices of healthcare systems, which generally rely on self-reported data. They also alert researchers of the importance of further genetic screening.

Along with genetic ancestry, environmental factors are also important to consider when evaluating disease risk. Often, certain populations may face levels of discrimination and disparities, which could have a large impact on care.

“The combination of your genetic risk and your environmental risk are the two most important things in determining whether you get a disease. It’s best for your doctor to have the best understanding of exactly what populations you might be coming from in order to assess things like disease risk or the need for genetic testing,” said lead author Christa Caggiano, a PhD student at UCLA Health, in a press release.

Similar efforts have also aimed to draw connections between genetics and disease risk.

For example, in March 2022,Scripps Research Institute created an app known as MyGeneRank that aimed to predict genetic risk for heart attack. The app did this using information from various sources such as 23andMe.

Using a smartphone, users could upload 23andMe information to the MyGeneRank app. The app then calculated the risk score for heart attack, mainly considering genetic risk factors for coronary artery disease. The app then followed up a year later to discuss the use of lipid-lowering medications among patients.

After reviewing information from app users, researchers found that those who did not take medication before using the app began to participate after receiving their genetic risk score.

“We now have the opportunity to integrate a person’s genetics into their cardiovascular health assessment to help them better understand their individualized risk and empower them to make the necessary modifications – including the addition of statin therapy - to their risk factor optimization plans,” said first author Evan Muse, MD, PhD, a cardiologist and lead for cardiovascular genomics at the Scripps Research Translational Institute, in a press release.

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Firms' Perceived Cost of Capital

We study hand-collected data on firms’ perceptions of their cost of capital. Firms with higher perceived cost of capital earn higher returns on invested capital and invest less, suggesting that the perceived cost of capital shapes long-run capital allocation. The perceived cost of capital is partially related to the true cost of capital, which is determined by risk premia and interest rates, but there are also large deviations between the perceived and true cost of capital. Only 20% of the variation in the perceived cost of capital is justified by variation in the true cost of capital. The remaining 80% reflects deviations that are consistent with managers making mistakes. These deviations lead to misallocation of capital that lowers long-run aggregate productivity by 5% in a benchmark model. Forcing all firms to apply the same cost of capital would improve the allocation of capital relative to current corporate practice. The deviations in the perceived cost of capital challenge standard models, in particular the production-based asset pricing paradigm, and lead us to reject the “Investment CAPM.” We describe actionable methods that allow firms to improve their perceptions and capital allocation.

We thank John Campbell, Thummim Cho, Kent Daniel (discussant), Gene Fama, Xavier Gabaix, Robin Greenwood, Sam Hanson, Tarek Hassan, John Heaton, Chang-Tai Hsieh, Ralph Koijen, Eben Lazarus, Christian Leuz, Lira Mota, Tyler Muir, Stefan Nagel, Lasse Pedersen, Thomas Philippon, Andrei Shleifer, Amir Sufi, Adi Sunderam, David Thesmar, Rob Vishny, Annette Vissing-Jorgensen, and Ivo Welch as well as many seminar and conference participants for useful comments. The research was supported by Asness Junior Faculty Fellowship, the Fama Faculty Fellowship, the Fama-Miller Center, and the Lee Economics Program Faculty Fellowship at the University of Chicago. We thank Rahul Chauhan, Sonali Mishra, and Esfandiar Rouhani for outstanding research support. This paper is a substantially revised version of an earlier paper entitled “Equity Factors and Firms’ Perceived Cost of Capital.” The views expressed herein are those of the authors and do not necessarily reflect the views of the National Bureau of Economic Research.

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Elnaz Basirian

New research on how to identify investments that produce delayed but real profits — not just those that produce short-term accounting profits.

In a well-functioning capital market, profits should be the sole criterion for firm survival; that is, firms reporting losses should disappear. Of late, however, loss-making firms are highly sought after by investors — often more than some profitable firms. Unicorns, or startups with valuations exceeding a billion dollars, are examples of such loss-making firms. What has changed over time? When and why did losses lose their meaning? The authors’ series of new research papers provide some answers, guiding managers to make the right investments: those that produce delayed but real profits — not just those that produce short-term accounting profits but decimate shareholder wealth in long run.

In 1979, psychologists Daniel Kahneman and Amos Tversky famously posited that losses loom larger than gains in human decision-making. For example, a dollar of loss affects our behavior more than a dollar of profits . Likewise, when a firm announces losses, its stock price declines more dramatically than it increases for the same dollar amount of profits. Investors abandon and lenders tend to stop financing loss-making firms , which then start restructuring their business lines and laying off employees. Some firms go even further, conducting M&A transactions without substance and “managing earnings” to report profits instead of a loss.

Vijay Govindarajan is the Coxe Distinguished Professor at Dartmouth College’s Tuck School of Business, an executive fellow at Harvard Business School, and faculty partner at the Silicon Valley incubator Mach 49. He is a New York Times and Wall Street Journal bestselling author. His latest book is Fusion Strategy: How Real-Time Data and AI Will Power the Industrial Future . His Harvard Business Review articles “ Engineering Reverse Innovations ” and “ Stop the Innovation Wars ” won McKinsey Awards for best article published in HBR. His HBR articles “ How GE Is Disrupting Itself ” and “ The CEO’s Role in Business Model Reinvention ” are HBR all-time top-50 bestsellers. Follow him on LinkedIn . vgovindarajan
Shivaram Rajgopal is the Roy Bernard Kester and T.W. Byrnes Professor of Accounting and Auditing and Vice Dean of Research at Columbia Business School. His research examines financial reporting and executive compensation issues and he is widely published in both accounting and finance.
Anup Srivastava holds Canada Research Chair in Accounting, Decision Making, and Capital Markets and is a full professor at Haskayne School of Business, University of Calgary. In a series of HBR articles, he examines the management implications of digital disruption. He specializes in the valuation and financial reporting challenges of digital companies. Follow Anup on LinkedIn .
Aneel Iqbal is an assistant professor at Thunderbird School of Global Management, Arizona State University. He examines the accounting measurement and financial disclosures for new-economy firms and incorporates his wide-ranging industry experience into his research and teaching. He is a seasoned accounting and finance professional with diverse experience in auditing, financial analysis, business advisory, performance management, and executive training. Follow Aneel on LinkedIn .
Elnaz Basirian is a PhD student at the Haskayne School of Business. She examines the influence and role of intangibles in accounting and finance, aimed at improving valuation and market efficiency. She brings a decade of work experience in international financial markets. Follow Elnaz on LinkedIn .

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Disease genetics articles from across Nature Portfolio

Disease genetics, of human, animal and plant diseases, investigates the consequences of pathogenic (host) genetic variants as the major causes of heritable disorders (monogenic diseases) as well as the consequences of genome variation in the population to the variable predisposition of the individual to complex diseases with infectious or environmental causes.

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Cancer genetics

Latest Research and Reviews

Mild phenotypes in patients with different deletions in the 3′ enhancer region of SHOX

Valancy Miranda
Pascale Sabeh
Philippe M. Campeau

A novel homozygous variant of the PIGK gene caused by paternal disomy in a patient with neurodevelopmental disorder, cerebellar atrophy, and seizures

Kenichiro Sadamitsu
Kumiko Yanagi
Hiromi Hirata

Altered chromatin topologies caused by balanced chromosomal translocation lead to central iris hypoplasia

Here, the authors identify a form of central iris hypoplasia affecting the pupillary zone. They suggest that noncoding structural variations can lead to Mendelian diseases by disrupting the 3D genome structure and resulting in altered gene expression.

Qingjiong Zhang

Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia

Here, the authors analyze the blood transcriptome of Kenyan children with severe malarial anemia and observe impaired immune responses and molecular activation of hypoxia and reactive oxygen species networks, providing insight into disease pathogenesis.

Samuel B. Anyona
Qiuying Cheng
Douglas J. Perkins

Identification of a founder effect involving n.197C>T variant in RMRP gene associated to cartilage-hair hypoplasia syndrome in Brazilian patients

Maria Eduarda Gomes
Fernanda Kehdy
Sayonara Gonzalez

Defining the variant-phenotype correlation in patients affected by Noonan syndrome with the RAF1 :c.770C>T p.(Ser257Leu) variant

Andrea Gazzin
Federico Fornari
Alessandro Mussa

News and Comment

Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)

In biomedical research, particularly for rare diseases (RDs), there is a critical need for model organisms to unravel the mechanistic basis of diseases, perform biomarker studies and develop potential therapeutic interventions. Within Solve-RD, an EU-funded research project with the aim of solving large numbers of previously unsolved RDs, the European Rare Disease Models & Mechanisms Network (RDMM-Europe) has been established.

Kornelia Ellwanger
Julie A. Brill

DYRK1A gene linked to heart defects in Down syndrome

A study shows that congenital heart defects in Down syndrome are in part caused by increased dosage of the DYRK1A gene, which lies on chromosome 21, leading to reduced proliferation and mitochondrial dysfunction in cardiomyocytes.

Irene Fernández-Ruiz

The role of the molecular autopsy in sudden cardiac death in young individuals

A molecular autopsy is undertaken in cases of sudden cardiac death with no definitive cause found after conventional autopsy, with the aim of identifying a pathological genetic variant that could account for the death. Greater awareness of malignant arrhythmias in the absence of structural changes in inherited cardiomyopathies has increased the applicability of molecular autopsies, and resulted in improved care of families but new challenges for clinicians.

Julia C. Isbister
Christopher Semsarian

New genes, pathways and therapeutic targets in autoinflammatory diseases

Studies in 2023 have described eight new monogenic autoinflammatory diseases and their accompanying disease-causing mutations, uncovering clinical phenotypes, pathogenic mechanisms and therapeutic targets. Researchers have identified autoinflammatory pathways linked to mitochondrial dysfunction or overactivation of SRC family kinases.

Riccardo Papa
Marco Gattorno

Comment on Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions

Johansson et al. recently described the genetic diagnosis of a large family with Gusatvson syndrome. The pathogenic variant in this family is an in-frame deletion in RBMX , also known as HNRNPG . This work expands the definition of the HNRNP-Related Neurodevelopmental Disorders and provides insights into analyzing the related conditions.

Madelyn A. Gillentine

Ocular oxidative changes and antioxidant therapy during spaceflight

Mouayad Masalkhi
Andrew G. Lee

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120+ Genetics Research Topics For All Kind Academic Papers
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120+ Genetics Research Topics for Your Projects
122 The Best Genetics Research Topics For Projects. The study of genetics takes place across different levels of the education system in academic facilities all around the world. It is an academic discipline that seeks to explain the mechanism of heredity and genes in living organisms. First discovered back in the 1850s, the study of genetics ...
119 Impressive Genetics Research Topics For College Students
Learn more about Genetics as a subject, how to choose one of the 119 genetics research topics in this field, and what you need to know while writing. Toll-free: +1 (877) 401-4335. Order Now. About; Prices; ... The next step after choosing genetics research paper topics is to identify relevant sources that will back your research. For Genetics ...
Genetics
Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including ...
Human Molecular Genetics and Genomics
In 1987, the New York Times Magazine characterized the Human Genome Project as the "biggest, costliest, most provocative biomedical research project in history." 2 But in the years between the ...
213 Genetics Research Topics & Essay Questions for College ...
213 Genetics Research Topics & Essay Questions for College and High School. Genetics studies how genes and traits pass from generation to generation. It has practical applications in many areas, such as genetic engineering, gene therapy, gene editing, and genetic testing. If you're looking for exciting genetics topics for presentation, you ...
Frontiers in Genetics
Genetic Horizons: Exploring genetic biomarkers in Therapy and Evolution with the Aid of Artificial Intelligence. Yiyin Zhang. GEORGIA DAMORAKI. Yirun Li. Shiyan Tang. 220 views. The most cited genetics and heredity journal, which advances our understanding of genes from humans to plants and other model organisms.
120+ Genetics Research Topics For All Kind Academic Papers
Human Genetics Topics For Research Papers. Human genetics entails studying inheritance in human beings. Here are some of the exciting human genetics topics for research papers. The Human Genome Project and its significance for understanding human genetics. Chromosomal abnormalities and their effects on human health.
Genetics research
Genetics research is the scientific discipline concerned with the study of the role of genes in traits such as the development of disease. It has a key role in identifying potential targets for ...
FOCUSED RESEARCH TOPICS
Recombination and genetic linkage: Gene expression: Genetic code: Gene regulation: Genetic change: Mutations: Natural selection and evolution: Medicine: Research methods: DNA sequencing and genomics: Genetic testing: Cell-free fetal DNA: Newborn screening: Diagnostic testing: Carrier testing: Preimplantation genetic diagnosis: Prenatal diagnosis
Genetics Research Paper Topics
Genetics Research Paper Topics. See our list of genetics research paper topics. Genetics is the branch of biology concerned with the science of heredity. The term heredity refers to the way in which specific characteristics are transmitted from one generation to the next. For example, we know that a tall mother and a tall father tend to have ...
Genetics
Genome Sequencing for Diagnosing Rare Diseases. M.H. Wojcik and OthersN Engl J Med 2024;390:1985-1997. Genetic diagnosis of rare diseases is made through a variety of methods. This study gauged ...
Genomics
Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the ...
Special Issue "Latest Review Papers in Molecular Genetics and Genomics
As we reflect on these diverse contributions in the Special Issue "Latest Advances in Molecular Genetics and Genomics (2023)", a common thread emerges: the intricate link between genetics, molecular mechanisms, and disease. These review papers collectively underscore the remarkable strides we have taken in unraveling the molecular ...
341 Genetics Topic Ideas to Write about & Essay Samples
Genetic Diseases: Sickle Cell Anemia. This genetic disorder research paper aims to elucidate the underlying molecular causes of SCA as well as its symptoms, inheritance, treatment, diagnosis, and prevalence in certain populations. Genetically Identical Twins and Different Disease Risk.
The Basics Of Choosing Genetic Research Paper Topics
A well-chosen topic leaves the reader with an in-depth understanding of a specified aspect of genetics, communicating complex scientific information and explaining it to a reader. Choosing the right topic will also reduce the difficulty of writing a good research paper by ensuring that the topic has enough credible resources to research.
Current Topics in Genetics Seminar Series
Distinguished scientists from across the nation are invited to present the latest research in a broad array of genetics topics. Lectures are attending by the Genetics students and faculty as well as being open to the scientific community. ... Enhancing the graduate student training, students of the Genetics Program study a paper on the lectures ...
105 Gene Topic Ideas to Write about & Essay Samples
The epidemiology of breast cancer and the methods of overcoming the growth of cancer cells are essential research topics in the current age. Gene Therapy: History, Description, Steps, and Future. The field of research concerning the modification of cells to cure certain diseases became known in the early 1970s.
Research Topics: Center for Genetic Medicine: Feinberg School of Medicine
Research Topics. The Center for Genetic Medicine's faculty members represent 33 departments or programs across three Northwestern University schools and three Feinberg-affiliated healthcare institutions. Faculty use genetics and molecular genetic approaches to understand biological processes for a diverse range of practical and clinical ...
132 Genetic Engineering Essay Topic Ideas & Examples
🔎 Genetic Engineering Research Topics. Gene Drives and Pest Control; The Benefits of Genetically Modified Organisms; ... It contains thousands of paper examples on a wide variety of topics, all donated by helpful students. You can use them for inspiration, an insight into a particular topic, a handy source of reference, or even just as a ...
Hot topics in human genetics : Journal of Human Genetics
The Journal of Human Genetics is proud to feature "Hot topics in human genetics" - a limited-time web focus bringing together research spanning three highly talked about topics, including ...
Tracking the Cellular and Genetic Roots of Neuropsychiatric Disease
The researchers used their findings to construct genetic regulatory and cellular communication networks, and a machine learning model built off of those networks was able to predict disease diagnosis from an individual's genetic information. Previous research has established a strong link between a person's genetics and their likelihood of ...
Advanced genetic tools help researchers ID new ...
In a recent study, a Yale-led research team described for the first time a rare neurodevelopmental syndrome that begins affecting patients during infancy, and typically causes developmental delays, severe seizures, cardiac dysrhythmia, and recurring infection.. After conducting a genetic analysis on 18 individuals with similar symptoms — but for whom there was no established diagnosis ...
Hidden DNA mechanisms of rare genetic diseases uncovered
Pacific Northwest Research Institute Summary: Researchers have uncovered how specific DNA rearrangements called inverted triplications contribute to the development of various genetic diseases.
CHARMed collaboration creates a potent therapy candidate for fatal
In other words, epigenetic editing could be an effective approach for treating genetic diseases such as inherited prion diseases. The challenge is creating a new type of therapy. Fortunately, the team had a good template for CHARM: a research tool called CRISPRoff that Weissman's group previously developed for silencing genes.
One Cohort at a Time: A New Perspective on the Declining Gender Pay Gap
This paper studies the interaction between the decrease in the gender pay gap and the stagnation in the careers of younger workers, analyzing data from the United States, Italy, Canada, and the United Kingdom. We propose a model of the labor market in which a larger supply of older workers can crowd out younger workers from top-paying positions.
Research Identifies Link Between Genetic Makeup and Disease Risk
Similar efforts have also aimed to draw connections between genetics and disease risk. For example, in March 2022,Scripps Research Institute created an app known as MyGeneRank that aimed to predict genetic risk for heart attack. The app did this using information from various sources such as 23andMe.
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Founded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, and business professionals.
Why Are Companies That Lose Money Still So Successful?
The authors' series of new research papers provide some answers, guiding managers to make the right investments: those that produce delayed but real profits — not just those that produce short ...
Disease genetics
DYRK1A gene linked to heart defects in Down syndrome. A study shows that congenital heart defects in Down syndrome are in part caused by increased dosage of the DYRK1A gene, which lies on ...

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This study included numerous individuals experiencing similar symptoms. Why did you suspect that this group of symptoms might in fact be a previously unknown syndrome?

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