biotechnology research proposal sample pdf

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Research Proposal Topics In Biotechnology

Biotechnology is a fascinating subject that blends biology and technology and provides a huge chance to develop new ideas. However, before pursuing a career in this field, a person needs to complete a number of studies and have a thorough knowledge of the matter. When we begin our career must we conduct study to discover some innovative innovations that could benefit people around the world. Biotechnology is one of a variety of sciences of life, including pharmacy. Students who are pursuing graduation, post-graduation or PhD must complete the research work and compose their thesis to earn the satisfaction in their education. When choosing a subject for biotechnology-related research it is important to choose one that is likely to inspire us. Based on our passion and personal preferences, the subject to study may differ.

What is Biotechnology?

In its most basic sense, biotechnology is the science of biology that enables technology Biotechnology harnesses the power of the biomolecular and cellular processes to create products and technologies that enhance our lives and the wellbeing of the planet. Biotechnology has been utilizing microorganisms' biological processes for over six thousand years to create useful food items like cheese and bread as well as to keep dairy products in good condition.

Modern biotechnology has created breakthrough products and technology to treat rare and debilitating illnesses help reduce our footprint on the environment and feed hungry people, consume less energy and use less and provide safer, more clean and productive industrial production processes.

Introduction

Biotechnology is credited with groundbreaking advancements in technological development and development of products to create sustainable and cleaner world. This is in large part due to biotechnology that we've made progress toward the creation of more efficient industrial manufacturing bases. Additionally, it assists in the creation of greener energy, feeding more hungry people and not leaving a large environmental footprint, and helping humanity fight rare and fatal diseases.

Our writing services for assignments within the field of biotechnology covers all kinds of subjects that are designed to test and validate the skills of students prior to awarding their certificates. We assist students to successfully complete their course in all kinds of biotechnology-related courses. This includes biological sciences for medical use (red) and eco-biotechnology (green) marine biotechnology (blue) and industrial biotechnology (white).

What do we hope to gain from all these Initiatives?

Our primary goal in preparing this list of the top 100 biotechnology assignment subjects is to aid students in deciding on effective time management techniques. We've witnessed a large amount of cases where when looking for online help with assignments with the topic, examining sources of information, and citing the correct order of reference students find themselves stuck at various points. In the majority of cases, students have difficulty even to get through their dilemma of choosing a topic. This is why we contribute in our effort to help make the process easier for students in biotech quickly and efficiently. Our students are able to save time and energy in order to help them make use of the time they are given to write the assignment with the most appropriate topics.

Let's look at some of the newest areas of biotechnology research and the related areas.

• Renewable Energy Technology Management Promoting Village
• Molasses is a molasses-based ingredient that can be used to produce and the treatment of its effluent
• Different ways to evapotranspirate
• Scattering Parameters of Circulator Bio-Technology
• Renewable Energy Technology Management Promoting Village.

Structural Biology of Infectious Diseases

A variety of studies are being conducted into the techniques used by pathogens in order to infect humans and other species and for designing strategies for countering the disease. The main areas that are available to study by biotech researchers include:

• inlA from Listeria monocytogenes when combined with E-cadherin from humans.
• InlC in Listeria monocytogenes that are multipart with human Tuba.
• Phospholipase PatA of Legionella pnemophila.
• The inactivation process of mammalian TLR2 by inhibiting antibody.
• There are many proteins that come originate from Mycobacterium tuberculosis.

Plant Biotechnology

Another significant area for research in biotechnology for plants is to study the genetic causes of the plant's responses to scarcity and salinity, which have a significant impact on yields of the crop and food.

• Recognition and classification of genes that influence the responses of plants to drought and salinity.
• A component of small-signing molecules in plants' responses to salinity and drought.
• Genetic enhancement of plant sensitivity salinity and drought.

Pharmacogenetics

It's also a significant area for conducting research in biotechnology. One of the most important reasons for doing so could be the identification of various genetic factors that cause differences in drug effectiveness and susceptibility for adverse reactions. Some of the subjects which can be studied are,

• Pharmacogenomics of Drug Transporters
• Pharmacogenomics of Metformin's response to type II mellitus
• The pharmacogenomics behind anti-hypertensive medicines
• The Pharmacogenomics of anti-cancer drugs

Forensic DNA

A further area of research in biotechnology research is the study of the genetic diversity of humans for its applications in criminal justice. Some of the topics that could be studied include,

• Y-chromosome Forensic Kit, Development of commercial prototype.
• Genetic testing of Indels in African populations.
• The Y-chromosome genotyping process is used for African populations.
• Study of paternal and maternal ancestry of mixed communities in South Africa.
• The study of the local diversity in genetics using highly mutating Y-STRs and Indels.
• South African Innocence Project: The study of DNA extracted from historical crime scene.
• Nanotechnology is a new technology that can be applied to DNA genotyping.
• Nanotechnology methods to isolate DNA.

Food Biotechnology

It is possible to conduct research in order to create innovative methods and processes in the fields of food processing and water. The most fascinating topics include:

• A molecular-based technology that allows for the rapid identification and detection of foodborne pathogens in intricate food chains.
• The effects of conventional and modern processing techniques on the bacteria that are associated with Aspalathus lineriasis.
• DNA-based identification of species of animals that are present in meat products that are sold raw.
• The phage assay and PCR are used to detect and limit the spread of foodborne pathogens.
• Retention and elimination of pathogenic, heat-resistant and other microorganisms that are treated by UV-C.
• Analysis of an F1 generation of the cross Bon Rouge x Packham's Triumph by Simple Sequence Repeat (SSR/microsatellite).
• The identification of heavy metal tolerant and sensitive genotypes
• Identification of genes that are involved in tolerance to heavy metals
• The isolation of novel growth-promoting bacteria that can help crops cope with heavy metal stress . Identification of proteins that signal lipids to increase the tolerance of plants to stress from heavy metals

This topic includes high-resolution protein expression profiling for the investigation of proteome profiles. The following are a few of the most fascinating topics:

• The identification and profile of stress-responsive proteins that respond to abiotic stress in Arabidopsis Thalian and Sorghum bicolor.
• Analyzing sugar biosynthesis-related proteins in Sorghum bicolor, and study of their roles in drought stress tolerance
• Evaluation of the viability and long-term sustainability of Sweet Sorghum for bioethanol (and other by-products) production in South Africa
• In the direction of developing an environmentally sustainable, low-tech hypoallergenic latex Agroprocessing System designed specifically especially for South African small-holder farmers.

Bioinformatics

This is an additional aspect of biotechnology research. The current trend is to discover new methods to combat cancer. Bioinformatics may help identify proteins and genes as well as their role in the fight against cancer. Check out some of the areas that are suitable to study.

• Prediction of anticancer peptides with HIMMER and the the support vector machine.
• The identification and verification of innovative therapeutic antimicrobial peptides for Human Immunodeficiency Virus In the lab and molecular method.
• The identification of biomarkers that are associated with cancer of the ovary using an molecular and in-silico method.
• Biomarkers identified in breast cancer, as possible therapeutic and diagnostic agents with a combination of molecular and in-silico approaches.
• The identification of MiRNA's as biomarkers for screening of cancerous prostates in the early stages an in-silico and molecular method
• Identification of putatively identified the genes present in breast cancer tissues as biomarkers for early detection of lobular and ductal breast cancers.
• Examining the significance of Retinoblastoma Binding Protein 6 (RBBP6) in the regulation of the cancer-related protein Y-Box Binding Protein 1 (YB-1).
• Examining the role played by Retinoblastoma Binding Protein 6 (RBBP6) in the regulation of the cancer suppressor p53 through Mouse Double Minute 2 (MDM2).
• Structural analysis of the anti-oxidant properties of the 1-Cys peroxiredoxin Prx2 found in the plant that resurrects itself Xerophyta viscosa.

Nanotechnology

This is a fascinating aspect of biotechnology, which can be used to identify effective tools to address the most serious health issues.

• Evaluation of cancer-specific peptides to determine their applications for the detection of cancer.
• The development of a quantum dot-based detection systems for breast cancer.
• The creation of targeted Nano-constructs for in vivo imaging as well as the treatment of tumors.
• Novel quinone compounds are being tested as anti-cancer medicines.
• Embedelin is delivered to malignant cells in a specific manner.
• The anti-cancer activities of Tulbaghia Violacea extracts were studied biochemically .
• Novel organic compounds are screened for their anti-cancer potential.
• To treat HIV, nanotechnology-based therapeutic techniques are being developed.

Top 100 Biotechnology Research Proposal Topics to Consider in 2022

We've prepared a list of the top 100 most suggested dissertation topics, which were compiled by our experts in research. They've made sure to offer a an extensive list of topics that cover all aspects of the topic. We hope that this list will meet all of the requirements for assistance with your dissertation . Let us start with our list of subjects, one at a time each one

• Achieving effective control of renewable power technologies to help the village
• The production of ethanol through the aid of molasses and the treatment of its effluent
• Different approaches and aspects of Evapotranspiration
• Its scattering parameter is biotechnology circulator
• The inactivation of mammalian TLR2 via an inhibiting antibody
• The number of proteins produced by Mycobacterium tuberculosis
• Recognition and classification of genes that shape the responses of plants to drought and salinity.
• The small sign molecules that are involved in the response that plants have to the effects of salinity as well as drought
• Genetic improvement of the plant's sensitivity to drought and saltiness
• The pharmacogenomics of drug transporters
• The anti-cancer drugs' pharmacogenomics are based on pharmac
• The pharmacogenomics of antihypertensive medications
• Indels genotyping of African populations
• Genomics of the Y-chromosomes of African populations
• The profiling of DNA extracted from historical crime scenes Consider the implications of South African Innocence Project
• Nanotechnology-related methods for DNA isolation
• Nanotechnology applications in the context of DNA genotyping
• Recognizing the heavy metals that are tolerant with genotypes that are sensitive.
• Genetic characteristics that play a role within the procedure of gaining tolerance to metals
• The animal's DNA is authenticated by the species by the commercial production of raw meat products
• The use of molecular-based technology is in the sense of detection and identification of foodborne pathogens in complicated food systems
• Assessing the effectiveness of cancer-specific peptides that are suitable for efficient implementations in the area of diagnosis and treatment for cancer
• Quantum Dot-based detection system is being developed in relation to a positive breast cancer diagnosis
• It is targeted delivery of the embelin to cancerous cells
• Exploring the potential of novel quinone compounds as anti-cancer agents
• Treatment strategies for treating HIV in addition to the significance of nanotechnology the treatment of HIV.
• A review of the medicinal value the antioxidants found in nature.
• An in-depth examination of the structure of COVID spike proteins
• A review of the immune response to the stem therapy using cells
• CRISPR-Cas9 technology to aid in the process of editing the genome
• Tissue engineering and delivery of drugs through the application of Chitosan
• Evaluation of beneficial effects of cancer vaccines
• Use of PacBio sequencing in relation to genome assembly of model organisms
• Examining the connection between mRNA suppression and its effect on the growth of stem cells
• Biomimicry is a method of identifying of cancer cells
• The sub-classification and characterisation of the Yellow enzymes
• The process of producing food products that are hypoallergenic and fermented.
• The production of hypoallergenic milk
• The purification process for the thermostable phytase
• Bioconversion of the cellulose produce products that are significant for industry
• The investigation of the gut microbiota of the model organisms
• The use of fungal enzymes for the manufacture of chemical glue
• A look at those inhibitors to exocellulase as well as endocellulase
• Examine the value of microorganisms to aid in the recovery of gas from shale.
• Examine the thorough analysis of the method of natural decomposition
• Examine ways to recycle bio-wastes
• Improved bio-remediation in the case of oil spills
• The process of gold biosorption is accomplished with the aid of the cyanobacterium
• A healthy equilibrium between the biotic and the abiotic elements by using biotechnological devices
• The measurement of the mercury level in fish by means of markers
• Exploring the biotechnological capabilities from Jellyfish related microbiomes Jellyfish related microbiome
• What is the role of marine fungi to aid in attempts to break down plastics and polymers?
• Examine the biotechnological possibilities that can be extracted of dinoflagellates
• Removing endosulfan residues using the use of biotechnology the agriculture sector
• The creation of the ELISA method for the detection of crop virus
• Enhancing the quality of drinking water by the aid of the E.coli consortium
• The characterisation of E.coli is its isolation from the feces of Zoo animals
• Enhancing the resistance of crops to the attack of insects
• The reduction of the expenditure on agriculture by using efficient bio-tools
• Are there the most efficient ways to stop erosion of soils using the help of biotechnology-based tools?
• What can biotechnology do to assist in increasing the levels of vitamin content in GM food items?
• Enhancing the distribution of pesticides by using biotechnology
• Comparing the biofortification of folate in various types of corpses
• Examine the photovoltaic-based generation of ocean-based crop
• What is the best way to use nanotechnology will improve the efficiency of the agriculture sector?
• Analyzing the mechanisms that govern resistance to water stresses in models of plants
• Production and testing of human immune boosters within the test organisms
• Comparing genomic analysis to the usefulness of tools intended for bioinformatics
• The Arabinogalactan protein sequence and its value in the field of computational methods
• Analyzing and interpreting gut microbiota from model organisms
• Different methods of purification of proteins A comparative analysis
• The diagnosis of microbes and their function in micro-arrays of oligonucleotide oligonu
• The use of diverse techniques within the biomedical research field that includes micro-arrays technology
• The use of microbial community to produce the greenhouse effect
• Evaluation of the computational properties of various proteins that are derived from the marine microbiota
• E.coli gene mapping through the help of different tools for microbial research
• Intensifying the strains of Cyanobacterium the aid of gene sequencing
• Assessment and description by computation of crystallized proteins that are found in the natural world.
• MTERF protein and the use of it to end the process of transcription that occurs in mitochondrial DNA inside algae
• Reverse column chromatography in phase and its use in the separation of proteins
• The study of the various proteins that are found within Mycobacterium leprae.
• A review of the methods that are ideal to ensure the success of cloning RNA
• Examine the most common mistakes of biotechnology in conserving the ecology and natural environment.
• Is there a method to ensure that the medicinal plants are free of insects? Discuss
• What are the dangers caused by pest resistant animals on birds and human beings?
• What are the many areas of biotechnology that remain unexplored in terms research?
• What's the future of biotechnology in the medical field?
• Recombinant DNA technology to develop of new medical treatments
• What is the reason for the type of bacteria that is used to make vaccines with the aid of biotechnology?
• How can biotechnology aid in the development of new medicines that are resistant to the mutations of viruses and bacteria?
• Is there a long-term treatment for cancer that is available in the near term? Biotechnology could play an essential role in this?
• What is the reason it is so important that students remember the DNA codes in biotechnology?
• How can we create hybrid seeds with assistance of biotechnology?
• How can one create resistant plants to pests and what are the benefits of these seeds in final yields in agriculture?
• Examine bio-magnification and its effects on the ecology
• What are the causes to the reasons ecologists do not approve the use of pest-resistant seed, even though they are in application in agriculture?
• How has biotechnology influenced the lives of farmers in developing countries?
• Biotechnology can be used to boost the yield of plant species?
• Examine the role played by biotechnology to increase the production of the seasonal crops
• Are there any adverse side effects associated with pharmaceutical drugs when they are manufactured with biotechnological techniques? Let the issue with real-world examples

We attempted to cover the essential topics needed for research work. Other topics are available that could be picked based on our interests, the facilities available and resources available for the research, as well as resources and time limits.

We have reached the end of this list. We feel it was beneficial in satisfying the selection criteria. Furthermore, the inclusion of biotechnology-related assignment themes was done in such a manner that they may help us with the requirements of assignment writing kinds and forms. The themes listed above can meet our demands for topic selection linked to aid with case studies and essay assistance, research paper writing help , or thesis writing help .

Frequently asked questions

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Some of biotechnology topics are:

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Research Proposal Example/Sample

Full Walkthrough + Free Proposal Template

In this video, we walk you through two successful (approved) research proposals , one for a Master’s-level project, and one for a PhD-level dissertation. We also start off by unpacking our free research proposal template and discussing the four core sections of a research proposal, so that you have a clear understanding of the basics before diving into the actual proposals.

• Research proposal example/sample – Master’s-level (PDF/Word)
• Research proposal example/sample – PhD-level (PDF/Word)
• Proposal template (Fully editable) 

If you’re working on a research proposal for a dissertation or thesis, you may also find the following useful:

• Research Proposal Bootcamp : Learn how to write a research proposal as efficiently and effectively as possible
• 1:1 Proposal Coaching : Get hands-on help with your research proposal

Research Proposal Example: Frequently Asked Questions

Are the sample proposals real.

Yes. The proposals are real and were approved by the respective universities.

Can I copy one of these proposals for my own research?

As we discuss in the video, every research proposal will be slightly different, depending on the university’s unique requirements, as well as the nature of the research itself. Therefore, you’ll need to tailor your research proposal to suit your specific context.

You can learn more about the basics of writing a research proposal here .

How do I get the research proposal template?

You can access our free proposal template here .

Is the proposal template really free?

Yes. There is no cost for the proposal template and you are free to use it as a foundation for your research proposal.

Where can I learn more about proposal writing?

For self-directed learners, our Research Proposal Bootcamp is a great starting point.

For students that want hands-on guidance, our private coaching service is recommended.

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Research proposal for PhD application biotechnology: Background literature writing

Challenges for research scholars in writing pharmaceutical research grant

A GUIDE TO CLINICAL RESEARCH WRITING ON PUBLIC HEALTH FOR CLINICAL RESEARCHERS

Preparing a concrete research proposal is an integral step ofthe PhD application process in Biotechnology. A well-structured research proposal highlights the significance of the study, defines the research problem, outlines the methodologies, and discusses the implications of the possible outcomes.The process of preparing a research proposal involves critical thinking and excellent communication of ideas. The review committee at the university evaluates the potential of the candidates and the feasibility of the study based on the proposal.

Sections of a Research Proposal

The format, requirements,and guidelines for preparing a research proposal depend on the institute and one can obtain this information from the official sources. Broadly, a research proposal consists of the following sections:

• Introduction which encompasses the background of the study bringing out the significance, knowledge gaps, and the research problem statement
• Specific objectives of the study(can include development of new methodologies to advance the Biotechnology field)
• Review of literature associated with the research topic
• Approaches and design of methodologies to address the research questions
• Timelines, resources, budgets
• Expected outcomes, their implications, and how the study advances the field

Apart from the scientific framework, parameters like timelines, resources, and budgets proposed for the project also decide the feasibility of conducting the research , and therefore must be realistic and attainable.An ideal research proposal will also be flexible in its execution. In addition, the applicant must keep in mind that the scope of the research project should preferably align with the ongoing work in the department.

Structure of a research proposal

Writing a research proposal poses several challenges and students sometime require guidance in translating their ideas to a solid proposal andassistancewhen faced with limited timeto develop the proposal.Using our research proposal writing services , students can collaborate with research proposal writers who provide help in writing and editing high quality proposals customised to their requirements. The hired research proposal writers are subject matter experts in the fields of Biotechnology, Medicine, and Life sciences with a PhD degreeand excellent scientific writing skills. Our research proposalservice provides high quality contentensuring plagiarism correction and guidance for developing all the sections of a proposal.

Background literature writing

In this section, we focus on how to effectively write background literature for a research proposal. Background literature is one of the foremost and important sections of a proposal that establishes the context of the research problem. A well-written background section will generateinterest about your research problem in the reader,who thereafter will be invested in the later sections of the proposal.

The background section in a proposal should cover the following points

• Introduce the research topic
• Historical or landmark developments in the field of research topic
• Progress and evolution of the field
• Current trends in the field
• Gaps in the existing knowledge, unmet needs, and missing links
• Developing and stating the research problem (problem statement)
• Justification of the need for the study
• Significance of the study and contribution to scientific knowledge

A key aspectof writing this section is the organisation of literature.To achieve this, one can adopt the funnel approach (Hofstee, 2006) by first covering the broader literature of the field and later tapering the focus to studies relevant to the specific topic of interest.The progress in the field should be presented in a logical and connected manner without deviating from the research topic of interest in Biotechnology. One can compare the different schools of thoughts and theories on the topic and discuss the advantages and limitations and put forth your point of view supported by evidence.

Importance of identifying research gaps

Reviewing relevant publications from the past 3-5 years will help determine the recent trends as well as understand the gaps in research from the limitations and future directions, as discussed by the authors. The identification of knowledge gaps in the field provides originality and innovation to the proposal. An in-depth understanding of the research topic enables the researcher to ascertain the importance of these knowledge gaps and convert them into significant research problems that required further investigation to advance the field. This provides a sound rationale for the study and later paves way for laying down the objectives of the study and designing methodologies to test the hypotheses. Often times in Biotechnology field, the prospective PhD student will be taking forward an existing project in the lab. In this context, the background literature will cover the latest findings from the laboratory and discuss the missing links and future directions to take it forward which will be addressed in the proposed study. This will also help in demonstrating expertise and experience in the field in your proposal which will work to your advantage.

The applicant should consider the following points while writing the background literature

• The background literature section should not be exhaustive and instead should discuss only relevant studies close to the research topic.
• One needs to critically review the literature and discuss the relevance of the findings, as opposed to plainly state the results of the studies by other research groups. This would highlight the critical thinking ability of the candidate which will be evaluated by the review committee.

In summary, a research proposal is the cornerstone for academic research, and the background literature section, in particular, documents how the research study advances the field and adds a paradigm to the existing scientific literature. A compelling research proposal with a well-researched background of the study can provide an edge to thePhD application and increase the chances of selection. We offer the best research proposal writing service (includes writing/editing/proofreading) that provide expert guidance in preparing a strong background literaturesection highlighting the recent trends and knowledge gaps which can definitely strengthen your Biotechnology research proposal.

• https://www.monash.edu/rlo/graduate-research-writing/write-the-thesis/writing-a-research-proposal
• https://canvas.hull.ac.uk/courses/779/pages/writing-the-review
• Libguides.usc.edu/writingguide/researchproposal
• https://www.biotecnika.org/2019/11/how-to-write-good-phd-proposal-phd-application/
• Sudheesh, K., Duggappa, D. R., &Nethra, S. S. (2016). How to write a research proposal? Indian J Anaesth, 60 (9), 631-634. doi: 10.4103/0019-5049.190617
• Hofstee, E. (2006). Constructing a good dissertation: A practical guide to finishing a Masters, MBA or PhD on Schedule. Sandton: EPE
• https://orsp.umich.edu/research-proposals-background-or-significance

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Importance Of Proofreading For Scientific Writing Methods and Significance

Statistical analyses of case-control studies

Selecting material (e.g. excipient, active pharmaceutical ingredient, packaging material) for drug development

Comments are closed.

Excellent opening paragraph stating why is the research important and leading to the research goals

Clear and concise presentation of research aims \(questions\)

Research plan is well \ detailed starting from third paragraph.

Pronoun problem: who is the "w\ e"? Earlier, "I" is very clear, but this "we" lacks a clear antecedent.

Writing tip: good use of "signa\ l" words \("first," "second"\) to organize information and highlight key points.

Contributors: P. Pazos, Searle Center for Teaching Excellence and P. Hirsch, The Writing Program, [email protected]

Posted: 2008

TITLE: The Mitochondrial Stress Response and the Communication of Stress Responses Between Subcellular Compart\ ments

Compelling presentation of preparation from courses and prior lab experience.

Very detailed presentation of techni\ ques learned that are relevant to the project

Writing tip: "data" is a p\ lural word. Say, "The data suggest. . . " and "they [meaning the data] indicate."

Overall comments:

Good quality proposal overall. The author clearly explains the aims a\ nd methods to carry out those aims.

Research question: Analysis of mitochondria's unfolding protein response and its crosstalk with other folding envir\ onments in the cell.

Compelling presentation of prior experience in courses and labs. Could include specific techniques learned.

Good use of citations and references

Suggestions:

Should add headings to make it more readable and add some structure.

10 Helpful Steps for Writing a Graduate Research Proposal

The road to obtain a graduate degree is unquestionably long. But we have ten incredibly helpful steps for writing your graduate research proposal. When you finally reach your destination, it will all be worthwhile.

As a graduate student, when you start your journey, you must write, present and defend a graduate research proposal in front of a committee of professors, also known as a graduate advisory committee.

A research proposal is usually short, with only fewer than ten pages, but it has to cover the proposed research in detail. After the committee approves it, you should follow the research plan explained in the research proposal to complete your research project.

Figure 1. The typical timeline in graduate school.

Why is it important to write a research proposal?

There are eight major reasons for graduate students to write a research proposal in graduate school:

• It's required by the graduate school before performing research.
• Students become more familiar with the research project
• They develop research skills and academic writing skills.
• Students develop literature review skills.
• Students learn how to identify the research problem, objective, research questions and hypothesis.
• They learn to explore different methods to collect and analyze data, and to select the most appropriate methods for solving research problems.
• They learn to design research experiments based on logical and chronological steps.
• The process nurtures critical thinking and logical reasoning skills.

What to include in a research proposal

The common elements to include in a good research proposal are:

• Title : The title of a research proposal should be clear and brief.
• Introduction : This part contains the background information of the proposed study leading to the research problem.
• Statement of purpose : This element should include the research objectives.
• Literature review : It should include an overview of findings from the previous studies, the gaps in the previous studies and the findings from a preliminary study.
• Research questions and hypothesis : This includes the research questions and hypothesis.
• Methodology : This element contains a full description of the research procedures, possible problems and alternatives strategies.
• The significance and impact of the study : This part shows how the proposed research will contribute to the field of study.

The 10 steps to writing an incredible research proposal

Below are ten steps for writing a research proposal:

1.Choose a research topic and develop a working title

Having a strong interest in your research topic will certainly help you to keep going when the journey becomes more challenging. The research topic is the subject of your research, which is a part of a broader field of study.

When you pick a research topic, find a topic that is not too narrow nor too broad. You can limit your topic, for example, by focusing on a certain treatment, population group, species, geographical area, period, methodology, or other specific factors.

After selecting a research topic, develop a working title to help you focus on your topic. As you write the proposal, you can keep changing the working title to formulate the perfect title.

2.Perform a literature review

The next step is to conduct a literature review. This step is important because when you write out the background information and knowledge gaps in your topic area, it will help you become more familiar with your research topic.

In addition, performing a literature review will direct you to a research problem . A research problem is a specific area of concern serving as the focus of your proposed research.

When performing a literature review, a graduate student can also discover some ideas for designing their research plan.

To help you conduct a literature review, answer the following questions below:

What have others done so far to solve the research problem?

Some helpful steps to answer this question:

• Understand the experimental designs from previous studies to help you design your own research experiments.
• Learn about appropriate sample sizes, data collection, and statistical analyses from previous studies.
• Investigate and make a list the reagents and equipment you’ll possibly need for your research.
• Learn the research questions, the findings, the impact and the significance of previous studies.
• Find out about any ethical concerns.

What additional studies are still needed to solve the research problem?

• Pay attention to the strength and limitation part of the discussion section of scientific articles. From this part, make notes about the limitations of previous studies to give you an idea about a potential research problem.
• Read the suggestions for future research part of scientific articles. That can serve as a call to action for you to solve those unanswered questions from previous studies.

3.Write an introduction

The introduction of your research proposal builds a framework for the research. This framework is the structure that supports your study and contains the background information. Its function is similar to the role of a foundation in supporting a building—if it is weak, a building will fall apart. Likewise, if your research lacks a strong background as a framework, it’s hard for others to see why it matters.

Writing your introduction can feel a little overwhelming. Where do you begin? How do you know you’re not missing anything?

You might want to read over our article:

How to Write an Effective Introduction Section of a Scientific Article

While the article is more specific to the introduction section of a formal research paper, there are some parts and tips you might find helpful.

4. Write research objectives or aims

In the next step, include research objectives or aims in the research proposal. A research objective is a goal you want to achieve in your research project ( Al-Riyami, 2008 ). Your research objectives must have a strong connection with your research problem.

When developing research objectives, identify all variables associated with the research problem. A variable in the research is a characteristic that you manipulate or observe in your experiment.

There are different types of variables, including an independent variable and dependent variable (Al-Riyami, 2008). An independent variable is a variable you can change in your experiment, whereas a dependent variable is a variable you observe in response to the independent variable. After identifying the variables, connect them to the research objective.

An example of a research objective: to determine the effect of different doses of a novel antibiotic X on the growth rate of some resistant bacterial strains . In this example, the independent variable is the treatment (the different doses of antibiotic X), and the dependent variable is the growth rate of some bacterial strains.

5.State a research question

The next step is to identify a research question. A research question is the key question you want to answer in your proposed study ( Farrugia et al ., 2010 ). A research project can contain several research questions.

Keep in mind that your research question must meet the criteria of a good research question, including specific, feasible, interesting, novel, ethical, and relevant (Farrugia et al ., 2010).

In term of feasibility, use current methods and technology to answer the question during your limited time in the graduate school.

An example of a research question : What doses of the antibiotic X are effective to inhibit the growth of some resistant bacterial strains?

6.Formulate a research hypothesis

After developing the research objectives and question, the next step is to formulate a research hypothesis. A research hypothesis is a statement of a possible research outcome.

Some criteria of a good hypothesis ( Prasad et al., 2010 ; Al-Riyami, 2008):

• Logical, precise, and clear
• Testable with research experiments
• Makes a prediction about the relationship between variables

An example of a research hypothesis: The new antibiotic X will significantly prevent the growth of some resistant bacterial strains.

7.Explain research methods

The methodology section containing proposed experimental procedures is required for a research proposal. This section has the detailed plan to solve the research problem. It also reflects the research questions and hypothesis.

After reviewing the credibility and validity of your research methods, your advisory committee will make a decision about the fate of your proposed study. Therefore, when writing the methodology section, keep in mind that others should be able to follow each step in the research design to perform the same experiment.

In this section, you should include these following key points:

• Experimental design : This is the research strategy you choose to solve your problem.
• Samples : It contains the description about the samples for each group of treatment in the proposed study.
• Sample size : This information is important to make sure your sample size is sufficient.
• Materials : It contains the reagents and chemicals needed in the proposed study.
• Equipment : This has the list of equipment needed for the proposed study.
• Protocols of data collection : It contains the procedures needed before collecting your data.
• Ethical issues and consent forms : You may need to include these if your proposed studies will need human participants.
• Data analysis : This part should include the steps to analyze the data.
• Gantt chart : This chart contains tasks in each research project with the timeline for each task.

8.Include potential problems and alternative strategies

When performing your study, you may encounter potential problems. Therefore, include some of the possible problems that may occur during your study and the potential solution for them. By doing so, you can use your backup plan to solve each potential problem when the problems actually occurs.

9.Conduct and include a preliminary study

Perform and include the findings from a preliminary study in your research proposal. A preliminary study is a small-scale pilot study, conducted to test the experimental design ahead of time and increase the likelihood of success. By including the findings from a preliminary study, your advisory committee can visualize and assess the feasibility of your large-scale study.

10.State the potential impact and significance

In the last paragraph of your research proposal, include the potential impact and significance of your proposed study.

The potential impact of your study means the changes that your proposed research would make. These changes can be positive or negative, immediate or long-term, and direct or indirect.

Whereas, the potential significance of your study means the contribution that your proposed research would make. For example, you can explain its contribution to the knowledge in your field of study.

After putting it all together, evaluate the entire proposal to make sure it is strong and well written.

Al-Riyami, A. (2008). How to prepare a Research Proposal. Oman Medical Journal, 23(2), 66–69. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC32824...

Benedetti, A. (n.d.). Research Guides: Advanced Research Methods: Writing a Research Proposal. Guides.library.ucla.edu. Retrieved March 17, 2021, from https://guides.library.ucla.edu/c.php?g=180334&p=1289236.

Crawford, L. (2020). LITERATURE-BASED DEFINITIONS OF CONCEPTUAL FRAMEWORKS. https://us.sagepub.com/sites/default/files/upm-assets/105274_book_item_105274.pdf.

Farrugia, P., Petrisor, B. A., Farrokhyar, F., & Bhandari, M. (2010). Practical tips for surgical research: Research questions, hypotheses and objectives. Canadian Journal of Surgery. Journal Canadien de Chirurgie, 53(4), 278–281. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29120...

How to choose a research area. (2016, April 8). ASCB. https://www.ascb.org/careers/choose-research-area/

How to Select a Research Topic | University of Michigan-Flint. (2019). Umflint.edu; UM-Flint. https://www.umflint.edu/library/how-select-research-topic.

How To Write a Proposal | Science & Quantitative Reasoning. (n.d.). Science.yalecollege.yale.edu. Retrieved March 17, 2021, from https://science.yalecollege.yale.edu/fellowships/how-write-proposal.

Jacobs, R. L. (2013). Developing a dissertation research problem: A guide for doctoral students in human resource development and adult education. New Horizons in Adult Education and Human Resource Development, 25(3), 103–117. https://doi.org/10.1002/nha3.20034.

Kivunja, C. (2018). Distinguishing between Theory, Theoretical Framework, and Conceptual Framework: A Systematic Review of Lessons from the Field. International Journal of Higher Education, 7(6), 44. https://doi.org/10.5430/ijhe.v7n6p44.

LibGuides: Writing a Research Proposal: Parts of a Proposal. (2017). Illinois.edu. https://guides.library.illinois.edu/c.php?g=504643&p=3454882.

LibGuides: Research Process: Finding a Research Topic. (2019). Libguides.com. https://ncu.libguides.com/researchprocess/researchtopic.

LibGuides: Research Process: Literature Gap and Future Research. (2012). Libguides.com. https://ncu.libguides.com/researchprocess/literaturegap.

Pajares, F. (n.d.). THE ELEMENTS OF A PROPOSAL. https://www.uky.edu/~eushe2/Pajares/ElementsOfaProposal.pdf.

Prasad, S., Rao, A., & Rehani, E. (2001). DEVELOPING HYPOTHESES & RESEARCH QUESTIONS DEVELOPING HYPOTHESIS AND RESEARCH QUESTIONS. https://www.public.asu.edu/~kroel/www500/hypothesi...

Shardlow, M., Batista-Navarro, R., Thompson, P., Nawaz, R., McNaught, J., & Ananiadou, S. (2018). Identification of research hypotheses and new knowledge from scientific literature. BMC Medical Informatics and Decision Making, 18(1). https://doi.org/10.1186/s12911-018-0639-1

Steps in Developing a Research Proposal. Open.lib.umn.edu; University of Minnesota Libraries Publishing edition, 2015. This edition adapted from a work originally produced in 2010 by a publisher who has requested that it not receive attribution. https://open.lib.umn.edu/writingforsuccess/chapter...

Vining, S. (2019, July 22). Dissertation Proposal | Genetics and Genomics. https://genetics.mcb.uconn.edu/dissertation-propos...

Writing a Research Plan. (2017, December 11). Science | AAAS. https://www.sciencemag.org/careers

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Current research in biotechnology: Exploring the biotech forefront

2019, Current Research in Biotechnology

Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/re-gions, and journals. The Web of Science Core Collection online database was searched to retrieve biotechnology articles published since 2017. In total, 12,351 publications were identified and analyzed. Over 8500 institutions contributed to these biotechnology publications, with the top 5 most productive ones scattered over France, China, the United States of America, Spain, and Brazil. Over 140 countries/regions contributed to the biotechnology research literature, led by the United States of America, China, Germany, Brazil, and India. Journal of Bioscience and Bioengineer-ing was the most productive journal in terms of number of publications. Metabolic engineering was among the most prevalent biotechnology study themes, and Escherichia coli and Saccharomyces cerevisiae were frequently used in biotechnology investigations, including the biosynthesis of useful biomolecules, such as myo-inositol (vitamin B8), mono-terpenes, adipic acid, astaxanthin, and ethanol. Nanoparticles and nanotechnology were identified too as emerging biotechnology research themes of great significance. Biotechnology continues to evolve and will remain a major driver of societal innovation and development.

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Scientists worldwide are continuing to discover unique properties of every day materials at the submicrometer scale. This size domain is better known as nanometer domain and technology concerned with this is known as nanotechnology that involves working with particles at nano level. One of the most important emerging fields of science in this centur y is Nanotechnology. It deals with designing, construction, investigation and utilization of systems at the nanoscale. The interface between nanotechnology and biotechnology is nanobiotechnology, which exploits nanotechnology and biotechnology to analyse a nd create nanobiosystems to meet a wide variety of challenges and develops a wide range of applications. Biotechnology gives us a way to understand biological system and to utilize our knowledge for industrial manufacturing. Nanotechnology has great potent ial and by the help of its application it can enhance the quality of life through in various fields like agriculture and the food system. Around the world, it has become the future of any nation. Important tools used in nanotechnology and application of nanobiotechnology in agriculture sector will be discussed in this review.

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This course includes significant instruction in scientific communications. During the term, Dr. Marilee Ogren-Balkema presents ten lectures on a range of reading, presentation and writing topics.

Background reading

Gopen, George D., and Judith A. Swan. “ The Science of Scientific Writing .” The American Scientist 78 (1990): 550-558.

Lectures on Scientific Communications

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IDH 1041: Honors Core - Social Sciences (Marten)

• Introduction
• Scholarly Articles
• Data & Statistics
• Research Proposal
• Annotated Bibliography
• Literature Review

Assignment Guidelines

The paper proposal describes and outlines a topic you expect to explore for your semester project. It is intended to be preliminary - this begins a conversation about your project with me and you can change your mind! Please also feel free to come chat with us to brainstorm some ideas if you’d like, we’re happy to help.

In this proposal you will:

• state your research question(s) (analytical, open ended RQ, rather than a descriptive, close ended one)
• introduce your topic and briefly describe it (including, perhaps, why your topic is an important one to address)
• identify and describe some potential challenges and/or questions you may have about your research project: Are you having a hard time finding scholarly sources? Do you think your topic might be too broad/narrow? Is some of the information/data confusing? Would you like your topic to go in a direction that better aligns with your interests, major, skill set, etc.?
• include the scholarly citations of at least two journal articles you plan to include in your project

The proposal should be between 400 and 600 words, double spaced, 12 pt. Times New Roman, 1” margins. I love subheads [e.g. Research Question(s), Topic Description, Questions and Concerns, References], but you are welcome to use the system of organization that works best for you, just make sure to include all components in a clear and organized way.

Choosing a Topic

• Opposing Viewpoints In Context (Gale) This link opens in a new window Opposing Viewpoints in Context is the premier online resource covering today’s hottest social issues, from Offshore Drilling to Climate Change, Health Care to Immigration. Opposing Viewpoints in Context helps students research, analyze and organize a broad variety of data for conducting research, completing writing assignments, preparing for debates, creating presentations and more.
• CQ Researcher This link opens in a new window CQ Researcher is often the first source that librarians recommend when researchers are seeking original, comprehensive reporting and analysis on issues in the news. CQ Researcher is noted for its in-depth, unbiased coverage of health, social trends, criminal justice, international affairs, education, the environment, technology, and the economy. Reports are published weekly in print and online 44 times a year by CQ Press, an imprint of SAGE Publications.
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