This document originally came from the Journal of Mammalogy courtesy of Dr. Ronald Barry, a former editor of the journal.

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How to Format a Scientific Paper

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Written by  Joanna Kimmerly-Smith

You've done the research. You've carefully recorded your lab results and compiled a list of relevant sources. You've even written a draft of your scientific, technical, or medical paper, hoping to get published in a reputable journal. But how do you format your paper to ensure that every detail is correct? If you're a scientific researcher or co-author looking to get your research published, read on to find out how to format your paper.

While it's true that you'll eventually need to tailor your research for your target journal, which will provide specific author guidelines for formatting the paper (see, for example, author guidelines for publications by Elsevier , PLOS ONE , and  mBio ), there are some formatting rules that are useful to know for your initial draft. This article will explore some of the formatting rules that apply to all scientific writing, helping you to follow the correct order of sections ( IMRaD ), understand the requirements of each section, find resources for standard terminology and units of measurement, and prepare your scientific paper for publication.

Format Overview

The four main elements of a scientific paper can be represented by the acronym IMRaD: introduction, methods, results, and discussion. Other sections, along with a suggested length,* are listed in the table below.

Cover Page

1 page

Discussion

4–6 pages

Abstract

1 paragraph (100–300 words)

Conclusion

1 paragraph

Keywords

3–7 words (approx.)

Acknowledgments

1–2 sentences

Introduction

1–2 pages

Conflicts of Interest/Originality Statement

1 sentence

Methods

2–3 pages

References

20–50 sources (2–4 pages)

Results

6–8 pages

Appendix/Supplementary Information

1–5 appendices

* Length guidelines are taken from https://www.elsevier.com/connect/11-steps-to-structuring-a-science-paper-editors-will-take-seriously#step6 .

Now, let's go through the main sections you might have to prepare to format your paper.

On the first page of the paper, you must present the title of the paper along with the authors' names, institutional affiliations, and contact information. The corresponding author(s) (i.e., the one[s] who will be in contact with the reviewers) must be specified, usually with a footnote or an asterisk (*), and their full contact details (e.g., email address and phone number) must be provided. For example:

Dr. Clara A. Bell 1, * and Dr. Scott C. Smith 2

1 University of Areopagitica, Department of Biology, Sometown, Somecountry

2 Leviathan University, Department of Biochemistry and Biomedical Sciences, Sometown, Somecountry

*[email protected]

FORMATTING TIPS:

  • If you are unsure of how to classify author roles (i.e., who did what), guidelines are available online. For example, American Geophysical Union (AGU) journals now recommend using Contributor Roles Taxonomy (CRediT), an online taxonomy for author contributions.

In this summary of your research, you must state your subject (i.e., what you did) and encapsulate the main findings and conclusions of your paper.

  • Do not add citations in an abstract (the reader might not be able to access your reference list).
  • Avoid using acronyms and abbreviations in the abstract, as the reader may not be familiar with them. Use full terms instead.

Below the abstract, include a list of key terms to help other researchers locate your study. Note that "keywords" is one word (with no space) and is followed by a colon:

Keywords : paper format, scientific writing.

  • Check whether "Keywords" should be italicized and whether each term should be capitalized.
  • Check the use of punctuation (e.g., commas versus semicolons, the use of the period at the end).
  • Some journals (e.g., IEEE ) provide a taxonomy of keywords. This aids in the classification of your research.

Introduction

This is the reader's first impression of your paper, so it should be clear and concise. Include relevant background information on your topic, using in-text citations as necessary. Report new developments in the field, and state how your research fills gaps in the existing research. Focus on the specific problem you are addressing, along with its possible solutions, and outline the limitations of your study. You can also include a research question, hypothesis, and/or objectives at the end of this section.

  • Organize your information from broad to narrow (general to particular). However, don't start too broad; keep the information relevant.
  • You can use in-text citations in this section to situate your research within the body of literature.

This is the part of your paper that explains how the research was done. You should relate your research procedures in a clear, logical order (i.e., the order in which you conducted the research) so that other researchers can reproduce your results. Simply refer to the established methods you used, but describe any procedures that are original to your study in more detail.

  • Identify the specific instruments you used in your research by including the manufacturer’s name and location in parentheses.
  • Stay consistent with the order in which information is presented (e.g., quantity, temperature, stirring speed, refrigeration period).

Now that you've explained how you gathered your research, you've got to report what you actually found. In this section, outline the main findings of your research. You need not include too many details, particularly if you are using tables and figures. While writing this section, be consistent and use the smallest number of words necessary to convey your statistics.

  • Use appendices or supplementary materials if you have too much data.
  • Use headings to help the reader follow along, particularly if your data are repetitive (but check whether your style guide allows you to use them).

In this section, you interpret your findings for the reader in relation to previous research and the literature as a whole. Present your general conclusions, including an assessment of the strengths and weaknesses of the research and the implications of your findings. Resolve the hypothesis and/or research question you identified in the introduction.

  • Use in-text citations to support your discussion.
  • Do not repeat the information you presented in the results or the introduction unless it is necessary for a discussion of the overall implications of the research.

This section is sometimes included in the last paragraph of the discussion. Explain how your research fits within your field of study, and identify areas for future research.

  • Keep this section short.

Acknowledgments

Write a brief paragraph giving credit to any institution responsible for funding the study (e.g., through a fellowship or grant) and any individual(s) who contributed to the manuscript (e.g., technical advisors or editors).

  • Check whether your journal uses standard identifiers for funding agencies (e.g., Elsevier's Funder Registry ).

Conflicts of Interest/Originality Statement

Some journals require a statement attesting that your research is original and that you have no conflicts of interest (i.e., ulterior motives or ways in which you could benefit from the publication of your research). This section only needs to be a sentence or two long.

Here you list citation information for each source you used (i.e., author names, date of publication, title of paper/chapter, title of journal/book, and publisher name and location). The list of references can be in alphabetical order (author–date style of citation) or in the order in which the sources are presented in the paper (numbered citations). Follow your style guide; if no guidelines are provided, choose a citation format and be consistent .

  • While doing your final proofread, ensure that the reference list entries are consistent with the in-text citations (i.e., no missing or conflicting information).
  • Many citation styles use a hanging indent and may be alphabetized. Use the styles in Microsoft Word to aid you in citation format.
  • Use EndNote , Mendeley , Zotero , RefWorks , or another similar reference manager to create, store, and utilize bibliographic information.

Appendix/Supplementary Information

In this optional section, you can present nonessential information that further clarifies a point without burdening the body of the paper. That is, if you have too much data to fit in a (relatively) short research paper, move anything that's not essential to this section.

  • Note that this section is uncommon in published papers. Before submission, check whether your journal allows for supplementary data, and don't put any essential information in this section.

Beyond IMRaD: Formatting the Details

Aside from the overall format of your paper, there are still other details to watch out for. The sections below cover how to present your terminology, equations, tables and figures, measurements, and statistics consistently based on the conventions of scientific writing.

Terminology

Stay consistent with the terms you use. Generally, short forms can be used once the full term has been introduced:

  • full terms versus acronyms (e.g., deoxyribonucleic acid versus DNA);
  • English names versus Greek letters (e.g., alpha versus α); and
  • species names versus short forms (e.g., Staphylococcus aureus versus S. aureus ).

One way to ensure consistency is to use standard scientific terminology. You can refer to the following resources, but if you're not sure which guidelines are preferred, check with your target journal.

  • For gene classification, use GeneCards , The Mouse Genome Informatics Database , and/or genenames.org .
  • For chemical nomenclature, refer to the International Union of Pure and Applied Chemistry (IUPAC) Compendium of Chemical Terminology (the Gold Book ) and the  IUPAC–IUB Combined Commission on Biochemical Nomenclature .
  • For marine species names, use the World Register of Marine Species (WoRMS) or the European Register of Marine Species (ERMS) .

Italics must be used correctly for scientific terminology. Here are a couple of formatting tips:

  • Species names, which are usually in Greek or Latin, are italicized (e.g., Staphylococcus aureus ).
  • Genes are italicized, but proteins aren't.

Whether in mathematical, scientific, or technical papers, equations follow a conventional format. Here are some tips for formatting your calculations:

  • Number each equation you present in the text, inserting the number in parentheses.

X + Y = 1                                                                                                                                               (1)

  • Check whether your target journal requires you to capitalize the word "Equation" or use parentheses for the equation number when you refer to equations within the text.

In Equation 1, X represents . . .

In equation (1), X represents . . .

(Note also that you should use italics for variables.)

  • Try using MathType or Equation Editor in Microsoft Word to type your equations, but use Unicode characters when typing single variables or mathematical operators (e.g., x, ≥, or ±) in running text. This makes it easier to edit your text and format your equations before publication.
  • In line with the above tip, remember to save your math equations as editable text and not as images in case changes need to be made before publication.

Tables and Figures

Do you have any tables, graphs, or images in your research? If so, you should become familiar with the rules for referring to tables and figures in your scientific paper. Some examples are presented below.

  • Capitalize the titles of specific tables and figures when you refer to them in the text (e.g., "see Table 3"; "in Figure 4").
  • In tables, stay consistent with the use of title case (i.e., Capitalizing Each Word) and sentence case (i.e., Capitalizing the first word).
  • In figure captions, stay consistent with the use of punctuation, italics, and capitalization. For example:

Figure 1. Classification of author roles.

Figure 2: taxonomy of paper keywords

Measurements

Although every journal has slightly different formatting guidelines, most agree that the gold standard for units of measurement is the International System of Units (SI) . Wherever possible, use the SI. Here are some other tips for formatting units of measurement:

  • Add spaces before units of measurement. For example, 2.5 mL not 2.5mL.
  • Be consistent with your units of measure (especially date and time). For example, 3 hours or 3 h.

When presenting statistical information, you must provide enough specific information to accurately describe the relationships among your data. Nothing is more frustrating to a reviewer than vague sentences about a variable being significant without any supporting details. The author guidelines for the journal Nature recommend that the following be included for statistical testing: the name of each statistical analysis, along with its n value; an explanation of why the test was used and what is being compared; and the specific alpha levels and P values for each test.

Angel Borja, writing for Elsevier publications, described the statistical rules for article formatting as follows:

  • Indicate the statistical tests used with all relevant parameters.
  • Use mean and standard deviation to report normally distributed data.
  • Use median and interpercentile range to report skewed data.
  • For numbers, use two significant digits unless more precision is necessary.
  • Never use percentages for very small samples.

Remember, you must be prepared to justify your findings and conclusions, and one of the best ways to do this is through factual accuracy and the acknowledgment of opposing interpretations, data, and/or points of view.

Even though you may not look forward to the process of formatting your research paper, it's important to present your findings clearly, consistently, and professionally. With the right paper format, your chances of publication increase, and your research will be more likely to make an impact in your field. Don't underestimate the details. They are the backbone of scientific writing and research.

One last tip: Before you submit your research, consider using our academic editing service for expert help with paper formatting, editing, and proofreading. We can tailor your paper to specific journal guidelines at your request.

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Issue Cover

Article Contents

Primacy of the research question, structure of the paper, writing a research article: advice to beginners.

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Thomas V. Perneger, Patricia M. Hudelson, Writing a research article: advice to beginners, International Journal for Quality in Health Care , Volume 16, Issue 3, June 2004, Pages 191–192, https://doi.org/10.1093/intqhc/mzh053

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Writing research papers does not come naturally to most of us. The typical research paper is a highly codified rhetorical form [ 1 , 2 ]. Knowledge of the rules—some explicit, others implied—goes a long way toward writing a paper that will get accepted in a peer-reviewed journal.

A good research paper addresses a specific research question. The research question—or study objective or main research hypothesis—is the central organizing principle of the paper. Whatever relates to the research question belongs in the paper; the rest doesn’t. This is perhaps obvious when the paper reports on a well planned research project. However, in applied domains such as quality improvement, some papers are written based on projects that were undertaken for operational reasons, and not with the primary aim of producing new knowledge. In such cases, authors should define the main research question a posteriori and design the paper around it.

Generally, only one main research question should be addressed in a paper (secondary but related questions are allowed). If a project allows you to explore several distinct research questions, write several papers. For instance, if you measured the impact of obtaining written consent on patient satisfaction at a specialized clinic using a newly developed questionnaire, you may want to write one paper on the questionnaire development and validation, and another on the impact of the intervention. The idea is not to split results into ‘least publishable units’, a practice that is rightly decried, but rather into ‘optimally publishable units’.

What is a good research question? The key attributes are: (i) specificity; (ii) originality or novelty; and (iii) general relevance to a broad scientific community. The research question should be precise and not merely identify a general area of inquiry. It can often (but not always) be expressed in terms of a possible association between X and Y in a population Z, for example ‘we examined whether providing patients about to be discharged from the hospital with written information about their medications would improve their compliance with the treatment 1 month later’. A study does not necessarily have to break completely new ground, but it should extend previous knowledge in a useful way, or alternatively refute existing knowledge. Finally, the question should be of interest to others who work in the same scientific area. The latter requirement is more challenging for those who work in applied science than for basic scientists. While it may safely be assumed that the human genome is the same worldwide, whether the results of a local quality improvement project have wider relevance requires careful consideration and argument.

Once the research question is clearly defined, writing the paper becomes considerably easier. The paper will ask the question, then answer it. The key to successful scientific writing is getting the structure of the paper right. The basic structure of a typical research paper is the sequence of Introduction, Methods, Results, and Discussion (sometimes abbreviated as IMRAD). Each section addresses a different objective. The authors state: (i) the problem they intend to address—in other terms, the research question—in the Introduction; (ii) what they did to answer the question in the Methods section; (iii) what they observed in the Results section; and (iv) what they think the results mean in the Discussion.

In turn, each basic section addresses several topics, and may be divided into subsections (Table 1 ). In the Introduction, the authors should explain the rationale and background to the study. What is the research question, and why is it important to ask it? While it is neither necessary nor desirable to provide a full-blown review of the literature as a prelude to the study, it is helpful to situate the study within some larger field of enquiry. The research question should always be spelled out, and not merely left for the reader to guess.

Typical structure of a research paper

Introduction
    State why the problem you address is important
    State what is lacking in the current knowledge
    State the objectives of your study or the research question
Methods
    Describe the context and setting of the study
    Specify the study design
    Describe the ‘population’ (patients, doctors, hospitals, etc.)
    Describe the sampling strategy
    Describe the intervention (if applicable)
    Identify the main study variables
    Describe data collection instruments and procedures
    Outline analysis methods
Results
    Report on data collection and recruitment (response rates, etc.)
    Describe participants (demographic, clinical condition, etc.)
    Present key findings with respect to the central research question
    Present secondary findings (secondary outcomes, subgroup analyses, etc.)
Discussion
    State the main findings of the study
    Discuss the main results with reference to previous research
    Discuss policy and practice implications of the results
    Analyse the strengths and limitations of the study
    Offer perspectives for future work
Introduction
    State why the problem you address is important
    State what is lacking in the current knowledge
    State the objectives of your study or the research question
Methods
    Describe the context and setting of the study
    Specify the study design
    Describe the ‘population’ (patients, doctors, hospitals, etc.)
    Describe the sampling strategy
    Describe the intervention (if applicable)
    Identify the main study variables
    Describe data collection instruments and procedures
    Outline analysis methods
Results
    Report on data collection and recruitment (response rates, etc.)
    Describe participants (demographic, clinical condition, etc.)
    Present key findings with respect to the central research question
    Present secondary findings (secondary outcomes, subgroup analyses, etc.)
Discussion
    State the main findings of the study
    Discuss the main results with reference to previous research
    Discuss policy and practice implications of the results
    Analyse the strengths and limitations of the study
    Offer perspectives for future work

The Methods section should provide the readers with sufficient detail about the study methods to be able to reproduce the study if so desired. Thus, this section should be specific, concrete, technical, and fairly detailed. The study setting, the sampling strategy used, instruments, data collection methods, and analysis strategies should be described. In the case of qualitative research studies, it is also useful to tell the reader which research tradition the study utilizes and to link the choice of methodological strategies with the research goals [ 3 ].

The Results section is typically fairly straightforward and factual. All results that relate to the research question should be given in detail, including simple counts and percentages. Resist the temptation to demonstrate analytic ability and the richness of the dataset by providing numerous tables of non-essential results.

The Discussion section allows the most freedom. This is why the Discussion is the most difficult to write, and is often the weakest part of a paper. Structured Discussion sections have been proposed by some journal editors [ 4 ]. While strict adherence to such rules may not be necessary, following a plan such as that proposed in Table 1 may help the novice writer stay on track.

References should be used wisely. Key assertions should be referenced, as well as the methods and instruments used. However, unless the paper is a comprehensive review of a topic, there is no need to be exhaustive. Also, references to unpublished work, to documents in the grey literature (technical reports), or to any source that the reader will have difficulty finding or understanding should be avoided.

Having the structure of the paper in place is a good start. However, there are many details that have to be attended to while writing. An obvious recommendation is to read, and follow, the instructions to authors published by the journal (typically found on the journal’s website). Another concerns non-native writers of English: do have a native speaker edit the manuscript. A paper usually goes through several drafts before it is submitted. When revising a paper, it is useful to keep an eye out for the most common mistakes (Table 2 ). If you avoid all those, your paper should be in good shape.

Common mistakes seen in manuscripts submitted to this journal

The research question is not specified
The stated aim of the paper is tautological (e.g. ‘The aim of this paper is to describe what we did’) or vague (e.g. ‘We explored issues related to X’)
The structure of the paper is chaotic (e.g. methods are described in the Results section)
The manuscripts does not follow the journal’s instructions for authors
The paper much exceeds the maximum number of words allowed
The Introduction is an extensive review of the literature
Methods, interventions and instruments are not described in sufficient detail
Results are reported selectively (e.g. percentages without frequencies, -values without measures of effect)
The same results appear both in a table and in the text
Detailed tables are provided for results that do not relate to the main research question
In the Introduction and Discussion, key arguments are not backed up by appropriate references
References are out of date or cannot be accessed by most readers
The Discussion does not provide an answer to the research question
The Discussion overstates the implications of the results and does not acknowledge the limitations of the study
The paper is written in poor English
The research question is not specified
The stated aim of the paper is tautological (e.g. ‘The aim of this paper is to describe what we did’) or vague (e.g. ‘We explored issues related to X’)
The structure of the paper is chaotic (e.g. methods are described in the Results section)
The manuscripts does not follow the journal’s instructions for authors
The paper much exceeds the maximum number of words allowed
The Introduction is an extensive review of the literature
Methods, interventions and instruments are not described in sufficient detail
Results are reported selectively (e.g. percentages without frequencies, -values without measures of effect)
The same results appear both in a table and in the text
Detailed tables are provided for results that do not relate to the main research question
In the Introduction and Discussion, key arguments are not backed up by appropriate references
References are out of date or cannot be accessed by most readers
The Discussion does not provide an answer to the research question
The Discussion overstates the implications of the results and does not acknowledge the limitations of the study
The paper is written in poor English

Huth EJ . How to Write and Publish Papers in the Medical Sciences , 2nd edition. Baltimore, MD: Williams & Wilkins, 1990 .

Browner WS . Publishing and Presenting Clinical Research . Baltimore, MD: Lippincott, Williams & Wilkins, 1999 .

Devers KJ , Frankel RM. Getting qualitative research published. Educ Health 2001 ; 14 : 109 –117.

Docherty M , Smith R. The case for structuring the discussion of scientific papers. Br Med J 1999 ; 318 : 1224 –1225.

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  • Research Paper Format | APA, MLA, & Chicago Templates

Research Paper Format | APA, MLA, & Chicago Templates

Published on November 19, 2022 by Jack Caulfield . Revised on January 20, 2023.

The formatting of a research paper is different depending on which style guide you’re following. In addition to citations , APA, MLA, and Chicago provide format guidelines for things like font choices, page layout, format of headings and the format of the reference page.

Scribbr offers free Microsoft Word templates for the most common formats. Simply download and get started on your paper.

APA |  MLA | Chicago author-date | Chicago notes & bibliography

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Table of contents

Formatting an apa paper, formatting an mla paper, formatting a chicago paper, frequently asked questions about research paper formatting.

The main guidelines for formatting a paper in APA Style are as follows:

  • Use a standard font like 12 pt Times New Roman or 11 pt Arial.
  • Set 1 inch page margins.
  • Apply double line spacing.
  • If submitting for publication, insert a APA running head on every page.
  • Indent every new paragraph ½ inch.

Watch the video below for a quick guide to setting up the format in Google Docs.

The image below shows how to format an APA Style title page for a student paper.

APA title page - student version (7th edition)

Running head

If you are submitting a paper for publication, APA requires you to include a running head on each page. The image below shows you how this should be formatted.

APA running head (7th edition)

For student papers, no running head is required unless you have been instructed to include one.

APA provides guidelines for formatting up to five levels of heading within your paper. Level 1 headings are the most general, level 5 the most specific.

APA headings (7th edition)

Reference page

APA Style citation requires (author-date) APA in-text citations throughout the text and an APA Style reference page at the end. The image below shows how the reference page should be formatted.

APA reference page (7th edition)

Note that the format of reference entries is different depending on the source type. You can easily create your citations and reference list using the free APA Citation Generator.

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The main guidelines for writing an MLA style paper are as follows:

  • Use an easily readable font like 12 pt Times New Roman.
  • Use title case capitalization for headings .

Check out the video below to see how to set up the format in Google Docs.

On the first page of an MLA paper, a heading appears above your title, featuring some key information:

  • Your full name
  • Your instructor’s or supervisor’s name
  • The course name or number
  • The due date of the assignment

MLA heading

Page header

A header appears at the top of each page in your paper, including your surname and the page number.

MLA page header

Works Cited page

MLA in-text citations appear wherever you refer to a source in your text. The MLA Works Cited page appears at the end of your text, listing all the sources used. It is formatted as shown below.

The format of the MLA Works Cited page

You can easily create your MLA citations and save your Works Cited list with the free MLA Citation Generator.

Generate MLA citations for free

The main guidelines for writing a paper in Chicago style (also known as Turabian style) are:

  • Use a standard font like 12 pt Times New Roman.
  • Use 1 inch margins or larger.
  • Place page numbers in the top right or bottom center.

Format of a Chicago Style paper

Chicago doesn’t require a title page , but if you want to include one, Turabian (based on Chicago) presents some guidelines. Lay out the title page as shown below.

Example of a Chicago Style title page

Bibliography or reference list

Chicago offers two citation styles : author-date citations plus a reference list, or footnote citations plus a bibliography. Choose one style or the other and use it consistently.

The reference list or bibliography appears at the end of the paper. Both styles present this page similarly in terms of formatting, as shown below.

Chicago bibliography

To format a paper in APA Style , follow these guidelines:

  • Use a standard font like 12 pt Times New Roman or 11 pt Arial
  • Set 1 inch page margins
  • Apply double line spacing
  • Include a title page
  • If submitting for publication, insert a running head on every page
  • Indent every new paragraph ½ inch
  • Apply APA heading styles
  • Cite your sources with APA in-text citations
  • List all sources cited on a reference page at the end

The main guidelines for formatting a paper in MLA style are as follows:

  • Use an easily readable font like 12 pt Times New Roman
  • Include a four-line MLA heading on the first page
  • Center the paper’s title
  • Use title case capitalization for headings
  • Cite your sources with MLA in-text citations
  • List all sources cited on a Works Cited page at the end

The main guidelines for formatting a paper in Chicago style are to:

  • Use a standard font like 12 pt Times New Roman
  • Use 1 inch margins or larger
  • Place page numbers in the top right or bottom center
  • Cite your sources with author-date citations or Chicago footnotes
  • Include a bibliography or reference list

To automatically generate accurate Chicago references, you can use Scribbr’s free Chicago reference generator .

Cite this Scribbr article

If you want to cite this source, you can copy and paste the citation or click the “Cite this Scribbr article” button to automatically add the citation to our free Citation Generator.

Caulfield, J. (2023, January 20). Research Paper Format | APA, MLA, & Chicago Templates. Scribbr. Retrieved August 21, 2024, from https://www.scribbr.com/research-paper/research-paper-format/

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Home » Research Paper Format – Types, Examples and Templates

Research Paper Format – Types, Examples and Templates

Table of Contents

Research Paper Formats

Research paper format is an essential aspect of academic writing that plays a crucial role in the communication of research findings . The format of a research paper depends on various factors such as the discipline, style guide, and purpose of the research. It includes guidelines for the structure, citation style, referencing , and other elements of the paper that contribute to its overall presentation and coherence. Adhering to the appropriate research paper format is vital for ensuring that the research is accurately and effectively communicated to the intended audience. In this era of information, it is essential to understand the different research paper formats and their guidelines to communicate research effectively, accurately, and with the required level of detail. This post aims to provide an overview of some of the common research paper formats used in academic writing.

Research Paper Formats

Research Paper Formats are as follows:

  • APA (American Psychological Association) format
  • MLA (Modern Language Association) format
  • Chicago/Turabian style
  • IEEE (Institute of Electrical and Electronics Engineers) format
  • AMA (American Medical Association) style
  • Harvard style
  • Vancouver style
  • ACS (American Chemical Society) style
  • ASA (American Sociological Association) style
  • APSA (American Political Science Association) style

APA (American Psychological Association) Format

Here is a general APA format for a research paper:

  • Title Page: The title page should include the title of your paper, your name, and your institutional affiliation. It should also include a running head, which is a shortened version of the title, and a page number in the upper right-hand corner.
  • Abstract : The abstract is a brief summary of your paper, typically 150-250 words. It should include the purpose of your research, the main findings, and any implications or conclusions that can be drawn.
  • Introduction: The introduction should provide background information on your topic, state the purpose of your research, and present your research question or hypothesis. It should also include a brief literature review that discusses previous research on your topic.
  • Methods: The methods section should describe the procedures you used to collect and analyze your data. It should include information on the participants, the materials and instruments used, and the statistical analyses performed.
  • Results: The results section should present the findings of your research in a clear and concise manner. Use tables and figures to help illustrate your results.
  • Discussion : The discussion section should interpret your results and relate them back to your research question or hypothesis. It should also discuss the implications of your findings and any limitations of your study.
  • References : The references section should include a list of all sources cited in your paper. Follow APA formatting guidelines for your citations and references.

Some additional tips for formatting your APA research paper:

  • Use 12-point Times New Roman font throughout the paper.
  • Double-space all text, including the references.
  • Use 1-inch margins on all sides of the page.
  • Indent the first line of each paragraph by 0.5 inches.
  • Use a hanging indent for the references (the first line should be flush with the left margin, and all subsequent lines should be indented).
  • Number all pages, including the title page and references page, in the upper right-hand corner.

APA Research Paper Format Template

APA Research Paper Format Template is as follows:

Title Page:

  • Title of the paper
  • Author’s name
  • Institutional affiliation
  • A brief summary of the main points of the paper, including the research question, methods, findings, and conclusions. The abstract should be no more than 250 words.

Introduction:

  • Background information on the topic of the research paper
  • Research question or hypothesis
  • Significance of the study
  • Overview of the research methods and design
  • Brief summary of the main findings
  • Participants: description of the sample population, including the number of participants and their characteristics (age, gender, ethnicity, etc.)
  • Materials: description of any materials used in the study (e.g., survey questions, experimental apparatus)
  • Procedure: detailed description of the steps taken to conduct the study
  • Presentation of the findings of the study, including statistical analyses if applicable
  • Tables and figures may be included to illustrate the results

Discussion:

  • Interpretation of the results in light of the research question and hypothesis
  • Implications of the study for the field
  • Limitations of the study
  • Suggestions for future research

References:

  • A list of all sources cited in the paper, in APA format

Formatting guidelines:

  • Double-spaced
  • 12-point font (Times New Roman or Arial)
  • 1-inch margins on all sides
  • Page numbers in the top right corner
  • Headings and subheadings should be used to organize the paper
  • The first line of each paragraph should be indented
  • Quotations of 40 or more words should be set off in a block quote with no quotation marks
  • In-text citations should include the author’s last name and year of publication (e.g., Smith, 2019)

APA Research Paper Format Example

APA Research Paper Format Example is as follows:

The Effects of Social Media on Mental Health

University of XYZ

This study examines the relationship between social media use and mental health among college students. Data was collected through a survey of 500 students at the University of XYZ. Results suggest that social media use is significantly related to symptoms of depression and anxiety, and that the negative effects of social media are greater among frequent users.

Social media has become an increasingly important aspect of modern life, especially among young adults. While social media can have many positive effects, such as connecting people across distances and sharing information, there is growing concern about its impact on mental health. This study aims to examine the relationship between social media use and mental health among college students.

Participants: Participants were 500 college students at the University of XYZ, recruited through online advertisements and flyers posted on campus. Participants ranged in age from 18 to 25, with a mean age of 20.5 years. The sample was 60% female, 40% male, and 5% identified as non-binary or gender non-conforming.

Data was collected through an online survey administered through Qualtrics. The survey consisted of several measures, including the Patient Health Questionnaire-9 (PHQ-9) for depression symptoms, the Generalized Anxiety Disorder-7 (GAD-7) for anxiety symptoms, and questions about social media use.

Procedure :

Participants were asked to complete the online survey at their convenience. The survey took approximately 20-30 minutes to complete. Data was analyzed using descriptive statistics, correlations, and multiple regression analysis.

Results indicated that social media use was significantly related to symptoms of depression (r = .32, p < .001) and anxiety (r = .29, p < .001). Regression analysis indicated that frequency of social media use was a significant predictor of both depression symptoms (β = .24, p < .001) and anxiety symptoms (β = .20, p < .001), even when controlling for age, gender, and other relevant factors.

The results of this study suggest that social media use is associated with symptoms of depression and anxiety among college students. The negative effects of social media are greater among frequent users. These findings have important implications for mental health professionals and educators, who should consider addressing the potential negative effects of social media use in their work with young adults.

References :

References should be listed in alphabetical order according to the author’s last name. For example:

  • Chou, H. T. G., & Edge, N. (2012). “They are happier and having better lives than I am”: The impact of using Facebook on perceptions of others’ lives. Cyberpsychology, Behavior, and Social Networking, 15(2), 117-121.
  • Twenge, J. M., Joiner, T. E., Rogers, M. L., & Martin, G. N. (2018). Increases in depressive symptoms, suicide-related outcomes, and suicide rates among U.S. adolescents after 2010 and links to increased new media screen time. Clinical Psychological Science, 6(1), 3-17.

Note: This is just a sample Example do not use this in your assignment.

MLA (Modern Language Association) Format

MLA (Modern Language Association) Format is as follows:

  • Page Layout : Use 8.5 x 11-inch white paper, with 1-inch margins on all sides. The font should be 12-point Times New Roman or a similar serif font.
  • Heading and Title : The first page of your research paper should include a heading and a title. The heading should include your name, your instructor’s name, the course title, and the date. The title should be centered and in title case (capitalizing the first letter of each important word).
  • In-Text Citations : Use parenthetical citations to indicate the source of your information. The citation should include the author’s last name and the page number(s) of the source. For example: (Smith 23).
  • Works Cited Page : At the end of your paper, include a Works Cited page that lists all the sources you used in your research. Each entry should include the author’s name, the title of the work, the publication information, and the medium of publication.
  • Formatting Quotations : Use double quotation marks for short quotations and block quotations for longer quotations. Indent the entire quotation five spaces from the left margin.
  • Formatting the Body : Use a clear and readable font and double-space your text throughout. The first line of each paragraph should be indented one-half inch from the left margin.

MLA Research Paper Template

MLA Research Paper Format Template is as follows:

  • Use 8.5 x 11 inch white paper.
  • Use a 12-point font, such as Times New Roman.
  • Use double-spacing throughout the entire paper, including the title page and works cited page.
  • Set the margins to 1 inch on all sides.
  • Use page numbers in the upper right corner, beginning with the first page of text.
  • Include a centered title for the research paper, using title case (capitalizing the first letter of each important word).
  • Include your name, instructor’s name, course name, and date in the upper left corner, double-spaced.

In-Text Citations

  • When quoting or paraphrasing information from sources, include an in-text citation within the text of your paper.
  • Use the author’s last name and the page number in parentheses at the end of the sentence, before the punctuation mark.
  • If the author’s name is mentioned in the sentence, only include the page number in parentheses.

Works Cited Page

  • List all sources cited in alphabetical order by the author’s last name.
  • Each entry should include the author’s name, title of the work, publication information, and medium of publication.
  • Use italics for book and journal titles, and quotation marks for article and chapter titles.
  • For online sources, include the date of access and the URL.

Here is an example of how the first page of a research paper in MLA format should look:

Headings and Subheadings

  • Use headings and subheadings to organize your paper and make it easier to read.
  • Use numerals to number your headings and subheadings (e.g. 1, 2, 3), and capitalize the first letter of each word.
  • The main heading should be centered and in boldface type, while subheadings should be left-aligned and in italics.
  • Use only one space after each period or punctuation mark.
  • Use quotation marks to indicate direct quotes from a source.
  • If the quote is more than four lines, format it as a block quote, indented one inch from the left margin and without quotation marks.
  • Use ellipses (…) to indicate omitted words from a quote, and brackets ([…]) to indicate added words.

Works Cited Examples

  • Book: Last Name, First Name. Title of Book. Publisher, Publication Year.
  • Journal Article: Last Name, First Name. “Title of Article.” Title of Journal, volume number, issue number, publication date, page numbers.
  • Website: Last Name, First Name. “Title of Webpage.” Title of Website, publication date, URL. Accessed date.

Here is an example of how a works cited entry for a book should look:

Smith, John. The Art of Writing Research Papers. Penguin, 2021.

MLA Research Paper Example

MLA Research Paper Format Example is as follows:

Your Professor’s Name

Course Name and Number

Date (in Day Month Year format)

Word Count (not including title page or Works Cited)

Title: The Impact of Video Games on Aggression Levels

Video games have become a popular form of entertainment among people of all ages. However, the impact of video games on aggression levels has been a subject of debate among scholars and researchers. While some argue that video games promote aggression and violent behavior, others argue that there is no clear link between video games and aggression levels. This research paper aims to explore the impact of video games on aggression levels among young adults.

Background:

The debate on the impact of video games on aggression levels has been ongoing for several years. According to the American Psychological Association, exposure to violent media, including video games, can increase aggression levels in children and adolescents. However, some researchers argue that there is no clear evidence to support this claim. Several studies have been conducted to examine the impact of video games on aggression levels, but the results have been mixed.

Methodology:

This research paper used a quantitative research approach to examine the impact of video games on aggression levels among young adults. A sample of 100 young adults between the ages of 18 and 25 was selected for the study. The participants were asked to complete a questionnaire that measured their aggression levels and their video game habits.

The results of the study showed that there was a significant correlation between video game habits and aggression levels among young adults. The participants who reported playing violent video games for more than 5 hours per week had higher aggression levels than those who played less than 5 hours per week. The study also found that male participants were more likely to play violent video games and had higher aggression levels than female participants.

The findings of this study support the claim that video games can increase aggression levels among young adults. However, it is important to note that the study only examined the impact of video games on aggression levels and did not take into account other factors that may contribute to aggressive behavior. It is also important to note that not all video games promote violence and aggression, and some games may have a positive impact on cognitive and social skills.

Conclusion :

In conclusion, this research paper provides evidence to support the claim that video games can increase aggression levels among young adults. However, it is important to conduct further research to examine the impact of video games on other aspects of behavior and to explore the potential benefits of video games. Parents and educators should be aware of the potential impact of video games on aggression levels and should encourage young adults to engage in a variety of activities that promote cognitive and social skills.

Works Cited:

  • American Psychological Association. (2017). Violent Video Games: Myths, Facts, and Unanswered Questions. Retrieved from https://www.apa.org/news/press/releases/2017/08/violent-video-games
  • Ferguson, C. J. (2015). Do Angry Birds make for angry children? A meta-analysis of video game influences on children’s and adolescents’ aggression, mental health, prosocial behavior, and academic performance. Perspectives on Psychological Science, 10(5), 646-666.
  • Gentile, D. A., Swing, E. L., Lim, C. G., & Khoo, A. (2012). Video game playing, attention problems, and impulsiveness: Evidence of bidirectional causality. Psychology of Popular Media Culture, 1(1), 62-70.
  • Greitemeyer, T. (2014). Effects of prosocial video games on prosocial behavior. Journal of Personality and Social Psychology, 106(4), 530-548.

Chicago/Turabian Style

Chicago/Turabian Formate is as follows:

  • Margins : Use 1-inch margins on all sides of the paper.
  • Font : Use a readable font such as Times New Roman or Arial, and use a 12-point font size.
  • Page numbering : Number all pages in the upper right-hand corner, beginning with the first page of text. Use Arabic numerals.
  • Title page: Include a title page with the title of the paper, your name, course title and number, instructor’s name, and the date. The title should be centered on the page and in title case (capitalize the first letter of each word).
  • Headings: Use headings to organize your paper. The first level of headings should be centered and in boldface or italics. The second level of headings should be left-aligned and in boldface or italics. Use as many levels of headings as necessary to organize your paper.
  • In-text citations : Use footnotes or endnotes to cite sources within the text of your paper. The first citation for each source should be a full citation, and subsequent citations can be shortened. Use superscript numbers to indicate footnotes or endnotes.
  • Bibliography : Include a bibliography at the end of your paper, listing all sources cited in your paper. The bibliography should be in alphabetical order by the author’s last name, and each entry should include the author’s name, title of the work, publication information, and date of publication.
  • Formatting of quotations: Use block quotations for quotations that are longer than four lines. Indent the entire quotation one inch from the left margin, and do not use quotation marks. Single-space the quotation, and double-space between paragraphs.
  • Tables and figures: Use tables and figures to present data and illustrations. Number each table and figure sequentially, and provide a brief title for each. Place tables and figures as close as possible to the text that refers to them.
  • Spelling and grammar : Use correct spelling and grammar throughout your paper. Proofread carefully for errors.

Chicago/Turabian Research Paper Template

Chicago/Turabian Research Paper Template is as folows:

Title of Paper

Name of Student

Professor’s Name

I. Introduction

A. Background Information

B. Research Question

C. Thesis Statement

II. Literature Review

A. Overview of Existing Literature

B. Analysis of Key Literature

C. Identification of Gaps in Literature

III. Methodology

A. Research Design

B. Data Collection

C. Data Analysis

IV. Results

A. Presentation of Findings

B. Analysis of Findings

C. Discussion of Implications

V. Conclusion

A. Summary of Findings

B. Implications for Future Research

C. Conclusion

VI. References

A. Bibliography

B. In-Text Citations

VII. Appendices (if necessary)

A. Data Tables

C. Additional Supporting Materials

Chicago/Turabian Research Paper Example

Title: The Impact of Social Media on Political Engagement

Name: John Smith

Class: POLS 101

Professor: Dr. Jane Doe

Date: April 8, 2023

I. Introduction:

Social media has become an integral part of our daily lives. People use social media platforms like Facebook, Twitter, and Instagram to connect with friends and family, share their opinions, and stay informed about current events. With the rise of social media, there has been a growing interest in understanding its impact on various aspects of society, including political engagement. In this paper, I will examine the relationship between social media use and political engagement, specifically focusing on how social media influences political participation and political attitudes.

II. Literature Review:

There is a growing body of literature on the impact of social media on political engagement. Some scholars argue that social media has a positive effect on political participation by providing new channels for political communication and mobilization (Delli Carpini & Keeter, 1996; Putnam, 2000). Others, however, suggest that social media can have a negative impact on political engagement by creating filter bubbles that reinforce existing beliefs and discourage political dialogue (Pariser, 2011; Sunstein, 2001).

III. Methodology:

To examine the relationship between social media use and political engagement, I conducted a survey of 500 college students. The survey included questions about social media use, political participation, and political attitudes. The data was analyzed using descriptive statistics and regression analysis.

Iv. Results:

The results of the survey indicate that social media use is positively associated with political participation. Specifically, respondents who reported using social media to discuss politics were more likely to have participated in a political campaign, attended a political rally, or contacted a political representative. Additionally, social media use was found to be associated with more positive attitudes towards political engagement, such as increased trust in government and belief in the effectiveness of political action.

V. Conclusion:

The findings of this study suggest that social media has a positive impact on political engagement, by providing new opportunities for political communication and mobilization. However, there is also a need for caution, as social media can also create filter bubbles that reinforce existing beliefs and discourage political dialogue. Future research should continue to explore the complex relationship between social media and political engagement, and develop strategies to harness the potential benefits of social media while mitigating its potential negative effects.

Vii. References:

  • Delli Carpini, M. X., & Keeter, S. (1996). What Americans know about politics and why it matters. Yale University Press.
  • Pariser, E. (2011). The filter bubble: What the Internet is hiding from you. Penguin.
  • Putnam, R. D. (2000). Bowling alone: The collapse and revival of American community. Simon & Schuster.
  • Sunstein, C. R. (2001). Republic.com. Princeton University Press.

IEEE (Institute of Electrical and Electronics Engineers) Format

IEEE (Institute of Electrical and Electronics Engineers) Research Paper Format is as follows:

  • Title : A concise and informative title that accurately reflects the content of the paper.
  • Abstract : A brief summary of the paper, typically no more than 250 words, that includes the purpose of the study, the methods used, the key findings, and the main conclusions.
  • Introduction : An overview of the background, context, and motivation for the research, including a clear statement of the problem being addressed and the objectives of the study.
  • Literature review: A critical analysis of the relevant research and scholarship on the topic, including a discussion of any gaps or limitations in the existing literature.
  • Methodology : A detailed description of the methods used to collect and analyze data, including any experiments or simulations, data collection instruments or procedures, and statistical analyses.
  • Results : A clear and concise presentation of the findings, including any relevant tables, graphs, or figures.
  • Discussion : A detailed interpretation of the results, including a comparison of the findings with previous research, a discussion of the implications of the results, and any recommendations for future research.
  • Conclusion : A summary of the key findings and main conclusions of the study.
  • References : A list of all sources cited in the paper, formatted according to IEEE guidelines.

In addition to these elements, an IEEE research paper should also follow certain formatting guidelines, including using 12-point font, double-spaced text, and numbered headings and subheadings. Additionally, any tables, figures, or equations should be clearly labeled and referenced in the text.

AMA (American Medical Association) Style

AMA (American Medical Association) Style Research Paper Format:

  • Title Page: This page includes the title of the paper, the author’s name, institutional affiliation, and any acknowledgments or disclaimers.
  • Abstract: The abstract is a brief summary of the paper that outlines the purpose, methods, results, and conclusions of the study. It is typically limited to 250 words or less.
  • Introduction: The introduction provides a background of the research problem, defines the research question, and outlines the objectives and hypotheses of the study.
  • Methods: The methods section describes the research design, participants, procedures, and instruments used to collect and analyze data.
  • Results: The results section presents the findings of the study in a clear and concise manner, using graphs, tables, and charts where appropriate.
  • Discussion: The discussion section interprets the results, explains their significance, and relates them to previous research in the field.
  • Conclusion: The conclusion summarizes the main points of the paper, discusses the implications of the findings, and suggests future research directions.
  • References: The reference list includes all sources cited in the paper, listed in alphabetical order by author’s last name.

In addition to these sections, the AMA format requires that authors follow specific guidelines for citing sources in the text and formatting their references. The AMA style uses a superscript number system for in-text citations and provides specific formats for different types of sources, such as books, journal articles, and websites.

Harvard Style

Harvard Style Research Paper format is as follows:

  • Title page: This should include the title of your paper, your name, the name of your institution, and the date of submission.
  • Abstract : This is a brief summary of your paper, usually no more than 250 words. It should outline the main points of your research and highlight your findings.
  • Introduction : This section should introduce your research topic, provide background information, and outline your research question or thesis statement.
  • Literature review: This section should review the relevant literature on your topic, including previous research studies, academic articles, and other sources.
  • Methodology : This section should describe the methods you used to conduct your research, including any data collection methods, research instruments, and sampling techniques.
  • Results : This section should present your findings in a clear and concise manner, using tables, graphs, and other visual aids if necessary.
  • Discussion : This section should interpret your findings and relate them to the broader research question or thesis statement. You should also discuss the implications of your research and suggest areas for future study.
  • Conclusion : This section should summarize your main findings and provide a final statement on the significance of your research.
  • References : This is a list of all the sources you cited in your paper, presented in alphabetical order by author name. Each citation should include the author’s name, the title of the source, the publication date, and other relevant information.

In addition to these sections, a Harvard Style research paper may also include a table of contents, appendices, and other supplementary materials as needed. It is important to follow the specific formatting guidelines provided by your instructor or academic institution when preparing your research paper in Harvard Style.

Vancouver Style

Vancouver Style Research Paper format is as follows:

The Vancouver citation style is commonly used in the biomedical sciences and is known for its use of numbered references. Here is a basic format for a research paper using the Vancouver citation style:

  • Title page: Include the title of your paper, your name, the name of your institution, and the date.
  • Abstract : This is a brief summary of your research paper, usually no more than 250 words.
  • Introduction : Provide some background information on your topic and state the purpose of your research.
  • Methods : Describe the methods you used to conduct your research, including the study design, data collection, and statistical analysis.
  • Results : Present your findings in a clear and concise manner, using tables and figures as needed.
  • Discussion : Interpret your results and explain their significance. Also, discuss any limitations of your study and suggest directions for future research.
  • References : List all of the sources you cited in your paper in numerical order. Each reference should include the author’s name, the title of the article or book, the name of the journal or publisher, the year of publication, and the page numbers.

ACS (American Chemical Society) Style

ACS (American Chemical Society) Style Research Paper format is as follows:

The American Chemical Society (ACS) Style is a citation style commonly used in chemistry and related fields. When formatting a research paper in ACS Style, here are some guidelines to follow:

  • Paper Size and Margins : Use standard 8.5″ x 11″ paper with 1-inch margins on all sides.
  • Font: Use a 12-point serif font (such as Times New Roman) for the main text. The title should be in bold and a larger font size.
  • Title Page : The title page should include the title of the paper, the authors’ names and affiliations, and the date of submission. The title should be centered on the page and written in bold font. The authors’ names should be centered below the title, followed by their affiliations and the date.
  • Abstract : The abstract should be a brief summary of the paper, no more than 250 words. It should be on a separate page and include the title of the paper, the authors’ names and affiliations, and the text of the abstract.
  • Main Text : The main text should be organized into sections with headings that clearly indicate the content of each section. The introduction should provide background information and state the research question or hypothesis. The methods section should describe the procedures used in the study. The results section should present the findings of the study, and the discussion section should interpret the results and provide conclusions.
  • References: Use the ACS Style guide to format the references cited in the paper. In-text citations should be numbered sequentially throughout the text and listed in numerical order at the end of the paper.
  • Figures and Tables: Figures and tables should be numbered sequentially and referenced in the text. Each should have a descriptive caption that explains its content. Figures should be submitted in a high-quality electronic format.
  • Supporting Information: Additional information such as data, graphs, and videos may be included as supporting information. This should be included in a separate file and referenced in the main text.
  • Acknowledgments : Acknowledge any funding sources or individuals who contributed to the research.

ASA (American Sociological Association) Style

ASA (American Sociological Association) Style Research Paper format is as follows:

  • Title Page: The title page of an ASA style research paper should include the title of the paper, the author’s name, and the institutional affiliation. The title should be centered and should be in title case (the first letter of each major word should be capitalized).
  • Abstract: An abstract is a brief summary of the paper that should appear on a separate page immediately following the title page. The abstract should be no more than 200 words in length and should summarize the main points of the paper.
  • Main Body: The main body of the paper should begin on a new page following the abstract page. The paper should be double-spaced, with 1-inch margins on all sides, and should be written in 12-point Times New Roman font. The main body of the paper should include an introduction, a literature review, a methodology section, results, and a discussion.
  • References : The reference section should appear on a separate page at the end of the paper. All sources cited in the paper should be listed in alphabetical order by the author’s last name. Each reference should include the author’s name, the title of the work, the publication information, and the date of publication.
  • Appendices : Appendices are optional and should only be included if they contain information that is relevant to the study but too lengthy to be included in the main body of the paper. If you include appendices, each one should be labeled with a letter (e.g., Appendix A, Appendix B, etc.) and should be referenced in the main body of the paper.

APSA (American Political Science Association) Style

APSA (American Political Science Association) Style Research Paper format is as follows:

  • Title Page: The title page should include the title of the paper, the author’s name, the name of the course or instructor, and the date.
  • Abstract : An abstract is typically not required in APSA style papers, but if one is included, it should be brief and summarize the main points of the paper.
  • Introduction : The introduction should provide an overview of the research topic, the research question, and the main argument or thesis of the paper.
  • Literature Review : The literature review should summarize the existing research on the topic and provide a context for the research question.
  • Methods : The methods section should describe the research methods used in the paper, including data collection and analysis.
  • Results : The results section should present the findings of the research.
  • Discussion : The discussion section should interpret the results and connect them back to the research question and argument.
  • Conclusion : The conclusion should summarize the main findings and implications of the research.
  • References : The reference list should include all sources cited in the paper, formatted according to APSA style guidelines.

In-text citations in APSA style use parenthetical citation, which includes the author’s last name, publication year, and page number(s) if applicable. For example, (Smith 2010, 25).

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Scientific Style and Format Citation Quick Guide

Scientific Style and Format presents three systems for referring to references (also known as citations) within the text of a journal article, book, or other scientific publication: 1) citation–sequence; 2) name–year; and 3) citation–name. These abbreviated references are called in-text references. They refer to a list of references at the end of the document.

The system of in-text references that you use will determine the order of references at the end of your document. These end references have essentially the same format in all three systems, except for the placement of the date of publication in the name–year system.

Though Scientific Style and Format now uses citation–sequence for its own references, each system is widely used in scientific publishing. Consult your publisher to determine which system you will need to follow.

Click on the tabs below for more information and to see some common examples of materials cited in each style, including examples of electronic sources. For numerous specific examples, see Chapter 29 of the 8th edition of Scientific Style and Format .

Citation–Sequence and Citation–Name

The following examples illustrate the citation–sequence and citation–name systems. The two systems are identical except for the order of references. In both systems, numbers within the text refer to the end references.

In citation–sequence, the end references are listed in the sequence in which they first appear within the text. For example, if a reference by Smith is the first one mentioned in the text, then the complete reference to the Smith work will be number 1 in the end references. The same number is used for subsequent in-text references to the same document.

In citation–name, the end references are listed alphabetically by author. Multiple works by the same author are listed alphabetically by title. The references are numbered in that sequence, such that a work authored by Adam is number 1, Brown is number 2, and so on. Numbers assigned to the end references are used for the in-text references regardless of the sequence in which they appear in the text of the work. For example, if a work by Zielinski is number 56 in the reference list, each in-text reference to Zielinski will be number 56 also.

List authors in the order in which they appear in the original text, followed by a period. Periods also follow article and journal title and volume or issue information. Separate the date from volume and issue by a semicolon. The location (usually the page range for the article) is preceded by a colon.

Author(s). Article title. Journal title. Date;volume(issue):location.

Journal titles are generally abbreviated according to the List of Title Word Abbreviations maintained by the ISSN International Centre. See Appendix 29.1 in Scientific Style and Format for more information.

For articles with more than 1 author, names are separated by a comma.

Smart N, Fang ZY, Marwick TH. A practical guide to exercise training for heart failure patients. J Card Fail. 2003;9(1):49–58.

For articles with more than 10 authors, list the first 10 followed by “et al.”

Pizzi C, Caraglia M, Cianciulli M, Fabbrocini A, Libroia A, Matano E, Contegiacomo A, Del Prete S, Abbruzzese A, Martignetti A, et al. Low-dose recombinant IL-2 induces psychological changes: monitoring by Minnesota Multiphasic Personality Inventory (MMPI). Anticancer Res. 2002;22(2A):727–732.

Volume with no issue or other subdivision

Laskowski DA. Physical and chemical properties of pyrethroids. Rev Environ Contam Toxicol. 2002;174:49–170.

Volume with issue and supplement

Gardos G, Cole JO, Haskell D, Marby D, Paine SS, Moore P. The natural history of tardive dyskinesia. J Clin Pharmacol. 1988;8(4 Suppl):31S–37S

Volume with supplement but no issue

Heemskerk J, Tobin AJ, Ravina B. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials. Nat Neurosci. 2002;5 Suppl:1027–1029.

Multiple issue numbers

Ramstrom O, Bunyapaiboonsri T, Lohmann S, Lehn JM. Chemical biology of dynamic combinatorial libraries. Biochim Biophys Acta. 2002;1572(2–3):178–186.

Issue with no volume

Sabatier R. Reorienting health and social services. AIDS STD Health Promot Exch. 1995;(4):1–3.

Separate information about author(s), title, edition, and publication by periods. The basic format is as follows:

Author(s). Title. Edition. Place of publication: publisher; date. Extent. Notes.

Extent can include information about pagination or number of volumes and is considered optional. Notes can include information of interest to the reader, such as language of publication other than English; such notes are optional.

Essential notes provide information about location, such as a URL for online works. See Chapter 29 for more information.

For books with more than 1 author, names are separated by a comma.

Ferrozzi F, Garlaschi G, Bova D. CT of metastases. New York (NY): Springer; 2000.

For books with more than 10 authors, list the first 10 followed by “et al.”

Wenger NK, Sivarajan Froelicher E, Smith LK, Ades PA, Berra K, Blumenthal JA, Certo CME, Dattilo AM, Davis D, DeBusk RF, et al. Cardiac rehabilitation. Rockville (MD): Agency for Health Care Policy and Research (US); 1995.

Organization as author

Advanced Life Support Group. Acute medical emergencies: the practical approach. London (England): BMJ Books; 2001.

Author(s) plus editor(s) or translator(s)

Klarsfeld A, Revah F. The biology of death: origins of mortality. Brady L, translator. Ithaca (NY): Cornell University Press; 2003.

Luzikov VN. Mitochondrial biogenesis and breakdown. Galkin AV, translator; Roodyn DB, editor. New York (NY): Consultants Bureau; 1985.

Chapter or other part of a book, same author(s)

Gawande A. The checklist manifesto: how to get things right. New York (NY): Metropolitan Books; 2010. Chapter 3, The end of the master builder; p. 48–71.

Chapter or other part of a book, different authors

Rapley R. Recombinant DNA and genetic analysis. In: Wilson K, Walker J, editors. Principles and techniques of biochemistry and molecular biology. 7th ed. New York (NY): Cambridge University Press; 2010. p. 195–262.

Multivolume work as a whole

Alkire LG, editor. Periodical title abbreviations. 16th ed. Detroit (MI): Thompson Gale; 2006. 2 vol. Vol. 1, By abbreviation; vol. 2, By title.

Dissertations and Theses

Lutz M. 1903: American nervousness and the economy of cultural change [dissertation]. [Stanford (CA)]: Stanford University; 1989.

Blanco EE, Meade JC, Richards WD, inventors; Ophthalmic Ventures, assignee. Surgical stapling system. United States patent US 4,969,591. 1990 Nov 13.

Weiss R. Study shows problems in cloning people: researchers find replicating primates will be harder than other mammals. Washington Post (Home Ed.). 2003 Apr 11;Sect. A:12 (col. 1).

Indicate a copyright date with a lowercase “c”.

Johnson D, editor. Surgical techniques in orthopaedics: anterior cruciate ligament reconstruction [DVD]. Rosemont (IL): American Academy of Orthopaedic Surgeons; c2002. 1 DVD.

Websites and Other Online Formats

References to websites and other online formats follow the same general principles as for printed references, with the addition of a date of update/revision (if available) along with an access date and a URL.

Title of Homepage. Edition. Place of publication: publisher; date of publication [date updated; date accessed]. Notes.

If no date of publication can be determined, use a copyright date (if available), preceded by “c”. Include the URL in the notes.

APSnet: plant pathology. St Paul (MN): American Phytopathological Association; c1994–2005 [accessed 2005 Jun 20]. http://www.apsnet.org/.

Online journal article

Author(s) of article. Title of article. Title of journal (edition). Date of publication [date updated; date accessed];volume(issue):location. Notes.

A DOI (Digital Object Identifier) may be included in the notes in addition to a URL, if available:

Savage E, Ramsay M, White J, Beard S, Lawson H, Hunjan R, Brown D. Mumps outbreaks across England and Wales in 2004: observational study. BMJ. 2005 [accessed 2005 May 31];330(7500):1119–1120. http://bmj.bmjjournals.com/cgi/reprint/330/7500/1119. doi:10.1136/bmj.330.7500.1119.

Author(s). Title of book. Edition. Place of publication: publisher; date of publication [date updated; date accessed]. Notes.

Brogden KA, Guthmille JM, editors. Polymicrobial diseases. Washington (DC): ASM Press; 2002 [accessed February 28, 2014]. http://www.ncbi.nlm.nih.gov/books/NBK2475/.

Author’s name. Title of post [descriptive word]. Title of blog. Date of publication. [accessed date]. URL.

Fogarty M. Formatting titles on Twitter and Facebook [blog]. Grammar Girl: Quick and Dirty Tips for Better Writing. 2012 Aug 14. [accessed 2012 Oct 19]. http://grammar.quickanddirtytips.com/formatting-titles-on-twitter-and-facebook.aspx.

Forthcoming or Unpublished Material

Not all forthcoming or unpublished sources are suitable for inclusion in reference lists. Check with your publisher if in doubt.

Forthcoming journal article or book

Journal article:

Farley T, Galves A, Dickinson LM, Perez MJ. Stress, coping, and health: a comparison of Mexican immigrants, Mexican-Americans, and non-Hispanic whites. J Immigr Health. Forthcoming 2005 Jul.

Goldstein DS. Adrenaline and the inner world: an introduction to scientific integrative medicine. Baltimore (MD): Johns Hopkins University Press. Forthcoming 2006.

Paper or poster presented at meeting

Unpublished presentations are cited as follows:

Antani S, Long LR, Thoma GR, Lee DJ. Anatomical shape representation in spine x-ray images. Paper presented at: VIIP 2003. Proceedings of the 3rd IASTED International Conference on Visualization, Imaging and Image Processing; 2003 Sep 8–10; Benalmadena, Spain.

Charles L, Gordner R. Analysis of MedlinePlus en Español customer service requests. Poster session presented at: Futuro magnifico! Celebrating our diversity. MLA ’05: Medical Library Association Annual Meeting; 2005 May 14–19; San Antonio, TX.

References to published presentations are cited much like contributions to books, with the addition of information about the date and place of the conference. See Chapter 29 for more information.

Personal communication

References to personal communication are placed in running text rather than as formal end references.

Permission is usually required and should be acknowledged in an “Acknowledgment” or “Notes” section at the end of the document.

. . . and most of these meningiomas proved to be inoperable (2003 letter from RS Grant to me; unreferenced, see “Notes”) while a few were not.

Name–Year

The following examples illustrate the name–year system. In this system (sometimes called the Harvard system), in-text references consist of the surname of the author or authors and the year of publication of the document. End references are unnumbered and appear in alphabetical order by author and year of publication, with multiple works by the same author listed in chronological order.

Each example of an end reference is accompanied here by an example of a corresponding in-text reference. For more details and many more examples, see Chapter 29 of Scientific Style and Format .

For the end reference, list authors in the order in which they appear in the original text. The year of publication follows the author list. Use periods to separate each element, including author(s), date of publication, article and journal title, and volume or issue information. Location (usually the page range for the article) is preceded by a colon.

Author(s). Date. Article title. Journal title. Volume(issue):location.

For the in-text reference, use parentheses and list author(s) by surname followed by year of publication.

(Author(s) Year)

For articles with 2 authors, names are separated by a comma in the end reference but by “and” in the in-text reference.

Mazan MR, Hoffman AM. 2001. Effects of aerosolized albuterol on physiologic responses to exercise in standardbreds. Am J Vet Res. 62(11):1812–1817.

(Mazan and Hoffman 2001)

For articles with 3 to 10 authors, list all authors in the end reference; in the in-text reference, list only the first, followed by “et al.”

Smart N, Fang ZY, Marwick TH. 2003. A practical guide to exercise training for heart failure patients. J Card Fail. 9(1):49–58.

(Smart et al. 2003)

For articles with more than 10 authors, list the first 10 in the end reference, followed by “et al.”

Pizzi C, Caraglia M, Cianciulli M, Fabbrocini A, Libroia A, Matano E, Contegiacomo A, Del Prete S, Abbruzzese A, Martignetti A, et al. 2002. Low-dose recombinant IL-2 induces psychological changes: monitoring by Minnesota Multiphasic Personality Inventory (MMPI). Anticancer Res. 22(2A):727–732.

(Pizzi et al. 2002)

Laskowski DA. 2002. Physical and chemical properties of pyrethroids. Rev Environ Contam Toxicol. 174:49–170.

(Laskowski 2002)

Gardos G, Cole JO, Haskell D, Marby D, Paine SS, Moore P. 1988. The natural history of tardive dyskinesia. J Clin Pharmacol. 8(4 Suppl):31S–37S.

(Gardos et al. 1988)

Heemskerk J, Tobin AJ, Ravina B. 2002. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials. Nat Neurosci. 5 Suppl:1027–1029.

(Heemskerk et al. 2002)

Ramstrom O, Bunyapaiboonsri T, Lohmann S, Lehn JM. 2002. Chemical biology of dynamic combinatorial libraries. Biochim Biophys Acta. 1572(2–3):178–186.

(Ramstrom et al. 2002)

Sabatier R. 1995. Reorienting health and social services. AIDS STD Health Promot Exch. (4):1–3.

(Sabatier 1995)

In the end reference, separate information about author(s), date, title, edition, and publication by periods. The basic format is as follows:

Author(s). Date. Title. Edition. Place of publication: publisher. Extent. Notes.

Extent can include information about pagination or number of volumes and is considered optional. Notes can include information of interest to the reader, such as language of publication other than English; such notes are optional. Essential notes provide information about location, such as a URL for online works. See Chapter 29 for more information.

For books with 2 authors, names are separated by a comma in the end reference but by “and” in the in-text reference.

Leboffe MJ, Pierce BE. 2010. Microbiology: laboratory theory and application. Englewood (CO): Morton Publishing Company.

(Leboffe and Pierce 2010)

For books with 3 to 10 authors, list all authors in the end reference; in the in-text reference, list only the first, followed by “et al.”

Ferrozzi F, Garlaschi G, Bova D. 2000. CT of metastases. New York (NY): Springer.

(Ferrozzi et al. 2000)

For books with more than 10 authors, list the first 10 in the end reference, followed by “et al.”

Wenger NK, Sivarajan Froelicher E, Smith LK, Ades PA, Berra K, Blumenthal JA, Certo CME, Dattilo AM, Davis D, DeBusk RF, et al. 1995. Cardiac rehabilitation. Rockville (MD): Agency for Health Care Policy and Research (US).

(Wenger et al. 1995)

[ALSG] Advanced Life Support Group. 2001. Acute medical emergencies: the practical approach. London (England): BMJ Books.

(ALSG 2001)

Klarsfeld A, Revah F. 2003. The biology of death: origins of mortality. Brady L, translator. Ithaca (NY): Cornell University Press.

Luzikov VN. 1985. Mitochondrial biogenesis and breakdown. Galkin AV, translator; Roodyn DB, editor. New York (NY): Consultants Bureau.

(Klarsfeld and Revah 2003)

(Luzikov 1985)

Gawande A. 2010. The checklist manifesto: how to get things right. New York (NY): Metropolitan Books. Chapter 3, The end of the master builder; p. 48–71.

(Gawande 2010)

Rapley R. 2010. Recombinant DNA and genetic analysis. In: Wilson K, Walker J, editors. Principles and techniques of biochemistry and molecular biology. 7th ed. New York (NY): Cambridge University Press. p. 195–262.

(Rapley 2010)

Alkire LG, editor. 2006. Periodical title abbreviations. 16th ed. Detroit (MI): Thompson Gale. 2 vol. Vol. 1, By abbreviation; vol. 2, By title.

(Alkire 2006)

Lutz M. 1989. 1903: American nervousness and the economy of cultural change [dissertation]. [Stanford (CA)]: Stanford University.

(Lutz 1989)

Blanco EE, Meade JC, Richards WD, inventors; Ophthalmic Ventures, assignee. 1990 Nov 13. Surgical stapling system. United States patent US 4,969,591.

(Blanco et al. 1990)

Weiss R. 2003 Apr 11. Study shows problems in cloning people: researchers find replicating primates will be harder than other mammals. Washington Post (Home Ed.). Sect. A:12 (col. 1).

(Weiss 2003)

Johnson D, editor. c2002. Surgical techniques in orthopaedics: anterior cruciate ligament reconstruction [DVD]. Rosemont (IL): American Academy of Orthopaedic Surgeons. 1 DVD.

(Johnson c2002)

Format for end reference:

Title of Homepage. Date of publication. Edition. Place of publication: publisher; [date updated; date accessed]. Notes.

APSnet: plant pathology online. c1994–2005. St Paul (MN): American Phytopathological Association; [accessed 2005 Jun 20]. http://www.apsnet.org/.

For the in-text reference, include only the first word or two of the title (enough to distinguish it from other titles in the reference list), followed by an ellipsis.

(APSnet . . . c1994–2005)

Author(s) of article. Date of publication. Title of article. Title of journal (edition). [date updated; date accessed];Volume(issue):location. Notes.

Savage E, Ramsay M, White J, Beard S, Lawson H, Hunjan R, Brown D. 2005. Mumps outbreaks across England and Wales in 2004: observational study. BMJ. [accessed 2005 May 31];330(7500):1119–1120. http://bmj.bmjjournals.com/cgi/reprint/330/7500/1119. doi:10.1136/bmj.330.7500.1119.

(Savage et al. 2005)

Author(s). Date of publication. Title of book. Edition. Place of publication: publisher; [date updated; date accessed]. Notes.

Brogden KA, Guthmille JM, editors. 2002. Polymicrobial diseases. Washington (DC): ASM Press; [accessed February 28, 2014]. http://www.ncbi.nlm.nih.gov/books/NBK2475/.

(Brogden and Guthmille 2002)

Author’s name. Date of publication. Title of post [descriptive word]. Title of blog. [accessed date]. URL.

Fogarty M. 2012 Aug 14. Formatting titles on Twitter and Facebook [blog]. Grammar Girl: Quick and Dirty Tips for Better Writing. [accessed 2012 Oct 19]. http://grammar.quickanddirtytips.com/formatting-titles-on-twitter-and-facebook.aspx.

(Fogarty 2012)

Farley T, Galves A, Dickinson LM, Perez MJ. Forthcoming 2005 Jul. Stress, coping, and health: a comparison of Mexican immigrants, Mexican-Americans, and non-Hispanic whites. J Immigr Health.

(Farley et al. 2005)

Goldstein DS. Forthcoming 2006. Adrenaline and the inner world: an introduction to scientific integrative medicine. Baltimore (MD): Johns Hopkins University Press.

(Goldstein 2006)

Antani S, Long LR, Thoma GR, Lee DJ. 2003. Anatomical shape representation in spine x-ray images. Paper presented at: VIIP 2003. Proceedings of the 3rd IASTED International Conference on Visualization, Imaging and Image Processing; Benalmadena, Spain.

Charles L, Gordner R. 2005. Analysis of MedlinePlus en Español customer service requests. Poster session presented at: Futuro magnifico! Celebrating our diversity. MLA ’05: Medical Library Association Annual Meeting; San Antonio, TX.

(Atani et al. 2003)

(Charles and Gordner 2005)

References to personal communication are placed in running text rather than as formal end references. Permission is usually required and should be acknowledged in an “Acknowledgment” or “Notes” section at the end of the document.

Scientific Style and Format, 8th Edition text © 2014 by the Council of Science Editors. Scientific Style and Format Online © 2014 by the Council of Science Editors.

ScienceDaily

Life from a drop of rain: New research suggests rainwater helped form the first protocell walls

A nobel-winning biologist, two engineering schools, and a vial of houston rainwater cast new light on the origin of life on earth.

One of the major unanswered questions about the origin of life is how droplets of RNA floating around the primordial soup turned into the membrane-protected packets of life we call cells.

A new paper by engineers from the University of Chicago's Pritzker School of Molecular Engineering (UChicago PME), the University of Houston's Chemical Engineering Department, and biologists from the UChicago Chemistry Department, have proposed a solution.

In the paper, published today in Science Advances , UChicago PME postdoctoral researcher Aman Agrawal and his co-authors -- including UChicago PME Dean Emeritus Matthew Tirrell and Nobel Prize-winning biologist Jack Szostak -- show how rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.

"This is a distinctive and novel observation," Tirrell said.

The research looks at "coacervate droplets" -- naturally occurring compartments of complex molecules like proteins, lipids, and RNA. The droplets, which behave like drops of cooking oil in water, have long been eyed as a candidate for the first protocells. But there was a problem. It wasn't that these droplets couldn't exchange molecules between each other, a key step in evolution, the problem was that they did it too well, and too fast.

Any droplet containing a new, potentially useful pre-life mutation of RNA would exchange this RNA with the other RNA droplets within minutes, meaning they would quickly all be the same. There would be no differentiation and no competition -- meaning no evolution.

And that means no life.

"If molecules continually exchange between droplets or between cells, then all the cells after a short while will look alike, and there will be no evolution because you are ending up with identical clones," Agrawal said.

Engineering a solution

Life is by nature interdisciplinary, so Szostak, the director of UChicago's Chicago Center for the Origins of Life, said it was natural to collaborate with both UChicago PME, UChicago's interdisciplinary school of molecular engineering, and the chemical engineering department at the University of Houston.

"Engineers have been studying the physical chemistry of these types of complexes -- and polymer chemistry more generally -- for a long time. It makes sense that there's expertise in the engineering school," Szostak said. "When we're looking at something like the origin of life, it's so complicated and there are so many parts that we need people to get involved who have any kind of relevant experience."

In the early 2000s, Szostak started looking at RNA as the first biological material to develop. It solved a problem that had long stymied researchers looking at DNA or proteins as the earliest molecules of life.

"It's like a chicken-egg problem. What came first?" Agrawal said. "DNA is the molecule which encodes information, but it cannot do any function. Proteins are the molecules which perform functions, but they don't encode any heritable information."

Researchers like Szostak theorized that RNA came first, "taking care of everything" in Agrawal's words, with proteins and DNA slowly evolving from it.

"RNA is a molecule which, like DNA, can encode information, but it also folds like proteins so that it can perform functions such as catalysis as well," Agrawal said.

RNA was a likely candidate for the first biological material. Coacervate droplets were likely candidates for the first protocells. Coacervate droplets containing early forms of RNA seemed a natural next step.

That is until Szostak poured cold water on this theory, publishing a paper in 2014 showing that RNA in coacervate droplets exchanged too rapidly.

"You can make all kinds of droplets of different types of coacervates, but they don't maintain their separate identity. They tend to exchange their RNA content too rapidly. That's been a long-standing problem," Szostak said. "What we showed in this new paper is that you can overcome at least part of that problem by transferring these coacervate droplets into distilled water -- for example, rainwater or freshwater of any type -- and they get a sort of tough skin around the droplets that restricts them from exchanging RNA content."

'A spontaneous combustion of ideas'

Agrawal started transferring coacervate droplets into distilled water during his PhD research at the University of Houston, studying their behavior under an electric field. At this point, the research had nothing to do with the origin of life, just studying the fascinating material from an engineering perspective.

"Engineers, particularly Chemical and Materials, have good knowledge of how to manipulate material properties such as interfacial tension, role of charged polymers, salt, pH control, etc.," said University of Houston Prof. Alamgir Karim, Agrawal's former thesis advisor and a senior co-author of the new paper. "These are all key aspects of the world popularly known as 'complex fluids' -- think shampoo and liquid soap."

Agrawal wanted to study other fundamental properties of coacervates during his PhD. It wasn't Karim's area of study, but Karim had worked decades earlier at the University of Minnesota under one of the world's top experts -- Tirrell, who later became founding dean of the UChicago Pritzker School of Molecular Engineering.

During a lunch with Agrawal and Karim, Tirrell brought up how the research into the effects of distilled water on coacervate droplets might relate to the origin of life on Earth. Tirrell asked where distilled water would have existed 3.8 billion years ago.

"I spontaneously said 'rainwater!' His eyes lit up and he was very excited at the suggestion," Karim said. "So, you can say it was a spontaneous combustion of ideas or ideation!"

Tirrell brought Agrawal's distilled water research to Szostak, who had recently joined the University of Chicago to lead what was then called the Origins of Life Initiative. He posed the same question he had asked Karim.

"I said to him, 'Where do you think distilled water could come from in a prebiotic world?'" Tirrell recalled. "And Jack said exactly what I hoped he would say, which was rain."

Working with RNA samples from Szostak, Agrawal found that transferring coacervate droplets into distilled water increased the time scale of RNA exchange -- from mere minutes to several days. This was long enough for mutation, competition, and evolution.

"If you have protocell populations that are unstable, they will exchange their genetic material with each other and become clones. There is no possibility of Darwinian evolution," Agrawal said. "But if they stabilize against exchange so that they store their genetic information well enough, at least for several days so that the mutations can happen in their genetic sequences, then a population can evolve."

Rain, checked

Initially, Agrawal experimented with deionized water, which is purified under lab conditions. "This prompted the reviewers of the journal who then asked what would happen if the prebiotic rainwater was very acidic," he said.

Commercial lab water is free from all contaminants, has no salt, and lives with a neutral pH perfectly balanced between base and acid. In short, it's about as far from real-world conditions as a material can get. They needed to work with a material more like actual rain.

What's more like rain than rain?

"We simply collected water from rain in Houston and tested the stability of our droplets in it, just to make sure what we are reporting is accurate," Agrawal said.

In tests with the actual rainwater and with lab water modified to mimic the acidity of rainwater, they found the same results. The meshy walls formed, creating the conditions that could have led to life.

The chemical composition of the rain falling over Houston in the 2020s is not the rain that would have fallen 750 million years after the Earth formed, and the same can be said for the model protocell system Agrawal tested. The new paper proves that this approach of building a meshy wall around protocells is possible and can work together to compartmentalize the molecules of life, putting researchers closer than ever to finding the right set of chemical and environmental conditions that allow protocells to evolve.

"The molecules we used to build these protocells are just models until more suitable molecules can be found as substitutes," Agrawal said. "While the chemistry would be a little bit different, the physics will remain the same."

  • Biochemistry Research
  • Environmental Issues
  • Origin of Life
  • Charles Darwin
  • Homo (genus)
  • Albertosaurus
  • Ichthyosaur
  • Neandertal interaction with Cro-Magnons
  • Structure of the Earth

Story Source:

Materials provided by University of Chicago . Original written by Paul Dailing. Note: Content may be edited for style and length.

Journal Reference :

  • Aman Agrawal, Aleksandar Radakovic, Anusha Vonteddu, Syed Rizvi, Vivian N. Huynh, Jack F. Douglas, Matthew V. Tirrell, Alamgir Karim, Jack W. Szostak. Did the exposure of coacervate droplets to rain make them the first stable protocells? Science Advances , 2024; 10 (34) DOI: 10.1126/sciadv.adn9657

Cite This Page :

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Library of Congress Science Tracer Bullet Inventory (1972-2013)

Introduction.

  • Tracer Bullet Title Index
  • Tracer Bullets: 1972-1980
  • Tracer Bullets: 1981-1990
  • Tracer Bullets: 1991-2000
  • Tracer Bullets: 2001-2010
  • Tracer Bullets: 2011-2013
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Author: Michelle Cadoree Bradley, Science Research Specialist, Science, Technology & Business Division

Created: June 2020

Last updated: April 5, 2021

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This guide provides an inventory of the Library of Congress Tracer Bullet series. In addition to their titles, Tracer Bullets were identified by a number indicating the year of publication, followed by the issue number; this inventory allows access to the titles by either title or by year and issue number. Links are provided when available to the Tracer Bullets that are accessible online, but some titles may be available only in print format.

What is a Science Tracer Bullet?

The Library of Congress Science Tracer Bullet series (ISSN 0090-5232) was an informal and irregular series of library pathfinders published from 1972-2013. They were designed to help someone begin to locate research materials on a subject about which they held only general knowledge.

These guides were produced by expert reference staff of the Science & Technology Division's Science Reference Section, and, on occasion, by guest librarians, consultants, interns, and volunteers. Most guides were aimed at the undergraduate level, however some, particularly those involving science fair projects, were written with parents and educators in mind. The Tracer Bullets were distributed as government documents to government depository libraries. In 1990 Omnigraphics, Inc. republished 173 of the titles in four volumes.

For more information on library pathfinders see " Library Pathfinders: a New Possibility for Cooperative Reference Service External ," by Charles H. Stevens, Marie P. Canfield, and Jeffrey J. Gardner, in College and Research Libraries News , v. 34, No 1 (1973).

What features are included in a Science Tracer Bullet?

One of the important aspects of the Science Tracer Bullet is that the progress of the information in the format of the bibliographic guide is supposed to mimic the research process itself. The prescribed format defines a scope, gives review articles and basic texts, and then leads the researcher on to suggestions for finding additional information.

The major features of a Science Tracer Bullet include:

  • a weighted list of subject headings, which can be used in searching a library card catalog
  • a list of basic texts
  • lists of bibliographies, state-of-the-art reports, conference proceedings, or technical reports
  • a list of journals in which one can usually find articles on a particular subject
  • a list of abstracting and indexing services, or databases, useful in finding journal articles and government publications
  • the names and addresses of organizations to contact for additional information
  • a list of selected internet sources

Why are they called "Tracer Bullets"?

"Tracer bullets," also called "tracer rounds," are usually loaded as every fifth round in machine gun belts. They provide essential information to soldiers firing at an enemy target by creating a line-of-sight that allows them to track the trajectory of their bullets and adjust their aim. Because these compilations were intended to put a reader "on target," they were called "tracer bullets."

About the Science Section

Part of the  Science & Business Reading Room  at the Library of Congress, the Science Section is the starting point for conducting research at the Library of Congress in the subject areas of science, medicine and engineering. Here, reference specialists in specific subject areas of science and engineering  assist patrons in formulating search strategies and gaining access to the information and materials contained in the Library's rich collections of science, medicine, and engineering materials.

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  • Advances in Methods and Practices in Psychological Science
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science research article format

Natural Experiments: Missed Opportunities for Causal Inference in Psychology Michael P. Grosz, Adam Ayaita, Ruben C. Arslan, et al.    

Knowledge about causal effects is essential for building useful theories and designing effective interventions. The preferred design for learning about causal effects is randomized experiments (i.e., studies in which the researchers randomly assign units to treatment and control conditions). However, randomized experiments are often unethical or unfeasible. On the other hand, observational studies are usually feasible but lack the random assignment that renders randomized experiments causally informative. Natural experiments can sometimes offer unique opportunities for dealing with this dilemma, allowing causal inference on the basis of events that are not controlled by researchers but that nevertheless establish random or as-if random assignment to treatment and control conditions. Yet psychological researchers have rarely exploited natural experiments. To remedy this shortage, we describe three main types of studies exploiting natural experiments (standard natural experiments, instrumental-variable designs, and regression-discontinuity designs) and provide examples from psychology and economics to illustrate how natural experiments can be harnessed. Natural experiments are challenging to find, provide information about only specific causal effects, and involve assumptions that are difficult to validate empirically. Nevertheless, we argue that natural experiments provide valuable causal-inference opportunities that have not yet been sufficiently exploited by psychologists.   

Tempered Expectations: A Tutorial for Calculating and Interpreting Prediction Intervals in the Context of Replications Jeffrey R. Spence, David J. Stanley   

Over the last decade, replication research in the psychological sciences has become more visible. One way that replication research can be conducted is to compare the results of the replication study with the original study to look for consistency, that is to say, to evaluate whether the original study is “replicable.” Unfortunately, many popular and readily accessible methods for ascertaining replicability, such as comparing significance levels across studies or eyeballing confidence intervals, are generally ill suited to the task of comparing results across studies. To address this issue, we present the prediction interval as a statistic that is effective for determining whether a replication study is inconsistent with the original study. We review the statistical rationale for prediction intervals, demonstrate hand calculations, and provide a walkthrough using an R package for obtaining prediction intervals for means, d values, and correlations. To aid the effective adoption of prediction intervals, we provide guidance on the correct interpretation of results when using prediction intervals in replication research.   

Interacting With Curves: How to Validly Test and Probe Interactions in the Real (Nonlinear) World Uri Simonsohn

Hypotheses involving interactions in which one variable modifies the association between another two are very common. They are typically tested relying on models that assume effects are linear, for example, with a regression like y = a + b x + c z + d x × z. In the real world, however, few effects are linear, invalidating inferences about interactions. For instance, in realistic situations, the false-positive rate can be 100% for detecting an interaction, and a probed interaction can reliably produce estimated effects of the wrong sign. In this article, I propose a revised toolbox for studying interactions in a curvilinear-robust manner, giving correct answers “even” when effects are not linear. It is applicable to most study designs and produces results that are analogous to those of current—often invalid—practices. The presentation combines statistical intuition, demonstrations with published results, and simulations. 

Performing Small-Telescopes Analysis by Resampling: Empirically Constructing Confidence Intervals and Estimating Statistical Power for Measures of Effect Size Samantha Costigan, John Ruscio, Jarret T. Crawford    

When new data are collected to check the findings of an original study, it can be challenging to evaluate replication results. The small-telescopes method is designed to assess not only whether the effect observed in the replication study is statistically significant but also whether this effect is large enough to have been detected in the original study. Unless both criteria are met, the replication either fails to support the original findings or the results are mixed. When implemented in the conventional manner, this small-telescopes method can be impractical or impossible to conduct, and doing so often requires parametric assumptions that may not be satisfied. We present an empirical approach that can be used for a variety of study designs and data-analytic techniques. The empirical approach to the small-telescopes method is intended to extend its reach as a tool for addressing the replication crisis by evaluating findings in psychological science and beyond. In the present tutorial, we demonstrate this approach using a Shiny app and R code and included an analysis of most studies (95%) replicated as part of the Open Science Collaboration’s Reproducibility Project in Psychology. In addition to its versatility, simulations demonstrate the accuracy and precision of the empirical approach to implementing small-telescopes analysis.   

Diagnosing the Misuse of the Bayes Factor in Applied Research Jorge N. Tendeiro, Henk A. L. Kiers, Rink Hoekstra, Tsz Keung Wong, Richard D. Morey    

Hypothesis testing is often used for inference in the social sciences. In particular, null hypothesis significance testing (NHST) and its p value have been ubiquitous in published research for decades. Much more recently, null hypothesis Bayesian testing (NHBT) and its Bayes factor have also started to become more commonplace in applied research. Following preliminary work by Wong and colleagues, we investigated how, and to what extent, researchers misapply the Bayes factor in applied psychological research by means of a literature study. Based on a final sample of 167 articles, our results indicate that, not unlike NHST and the [Formula: see text] value, the use of NHBT and the Bayes factor also shows signs of misconceptions. We consider the root causes of the identified problems and provide suggestions to improve the current state of affairs. This article is aimed to assist researchers in drawing the best inferences possible while using NHBT and the Bayes factor in applied research.   

Careless Responding: Why Many Findings Are Spurious or Spuriously Inflated Morgan D. Stosic, Brett A. Murphy, Fred Duong, Amber A. Fultz, Summer E. Harvey, Frank Bernieri    

Contrary to long-standing conventional wisdom, failing to exclude data from carelessly responding participants on questionnaires or behavioral tasks will frequently result in false-positive or spuriously inflated findings. Despite prior publications demonstrating this disturbing statistical confound, it continues to be widely underappreciated by most psychologists, including highly experienced journal editors. In this article, we aim to comprehensively explain and demonstrate the severity and widespread prevalence of careless responding’s (CR) inflationary effects in psychological research. We first describe when and why one can expect to observe the inflationary effect of unremoved CR data in a manner accessible to early graduate or advanced undergraduate students. To this end, we provide an online simulator tool and instructional videos for use in classrooms. We then illustrate realistic magnitudes of the severity of unremoved CR data by presenting novel reanalyses of data sets from three high-profile articles: We found that many of their published effects would have been meaningfully, sometimes dramatically, inflated if they had not rigorously screened out CR data. To demonstrate the frequency with which researchers fail to adequately screen for CR, we then conduct a systematic review of CR screening procedures in studies using paid online samples (e.g., MTurk) published across two prominent psychological-science journals. These findings suggest that most researchers either did not conduct any kind of CR screening or conducted only bare minimal screening. To help researchers avoid publishing spuriously inflated findings, we summarize best practices to help mitigate the threats of CR data.   

A Tutorial on Analyzing Ecological Momentary Assessment Data in Psychological Research With Bayesian (Generalized) Mixed-Effects Models Jonas Dora, Connor J. McCabe, Caspar J. van Lissa, Katie Witkiewitz, Kevin M. King    

In this tutorial, we introduce the reader to analyzing ecological momentary assessment (EMA) data as applied in psychological sciences with the use of Bayesian (generalized) linear mixed-effects models. We discuss practical advantages of the Bayesian approach over frequentist methods and conceptual differences. We demonstrate how Bayesian statistics can help EMA researchers to (a) incorporate prior knowledge and beliefs in analyses, (b) fit models with a large variety of outcome distributions that reflect likely data-generating processes, (c) quantify the uncertainty of effect-size estimates, and (d) quantify the evidence for or against an informative hypothesis. We present a workflow for Bayesian analyses and provide illustrative examples based on EMA data, which we analyze using (generalized) linear mixed-effects models to test whether daily self-control demands predict three different alcohol outcomes. All examples are reproducible, and data and code are available at https://osf.io/rh2sw/ . Having worked through this tutorial, readers should be able to adopt a Bayesian workflow to their own analysis of EMA data.   

The Causal Cookbook: Recipes for Propensity Scores, G-Computation, and Doubly Robust Standardization Arthur Chatton, Julia M. Rohrer    

Recent developments in the causal-inference literature have renewed psychologists’ interest in how to improve causal conclusions based on observational data. A lot of the recent writing has focused on concerns of causal identification (under which conditions is it, in principle, possible to recover causal effects?); in this primer, we turn to causal estimation (how do researchers actually turn the data into an effect estimate?) and modern approaches to it that are commonly used in epidemiology. First, we explain how causal estimands can be defined rigorously with the help of the potential-outcomes framework, and we highlight four crucial assumptions necessary for causal inference to succeed (exchangeability, positivity, consistency, and noninterference). Next, we present three types of approaches to causal estimation and compare their strengths and weaknesses: propensity-score methods (in which the independent variable is modeled as a function of controls), g-computation methods (in which the dependent variable is modeled as a function of both controls and the independent variable), and doubly robust estimators (which combine models for both independent and dependent variables). A companion R Notebook is available at github.com/ArthurChatton/CausalCookbook . We hope that this nontechnical introduction not only helps psychologists and other social scientists expand their causal toolbox but also facilitates communication across disciplinary boundaries when it comes to causal inference, a research goal common to all fields of research.   

Simulation-Based Power Analyses for the Smallest Effect Size of Interest: A Confidence-Interval Approach for Minimum-Effect and Equivalence Testing Paul Riesthuis    

Effect sizes are often used in psychology because they are crucial when determining the required sample size of a study and when interpreting the implications of a result. Recently, researchers have been encouraged to contextualize their effect sizes and determine what the smallest effect size is that yields theoretical or practical implications, also known as the “smallest effect size of interest” (SESOI). Having a SESOI will allow researchers to have more specific hypotheses, such as whether their findings are truly meaningful (i.e., minimum-effect testing) or whether no meaningful effect exists (i.e., equivalence testing). These types of hypotheses should be reflected in power analyses to accurately determine the required sample size. Through a confidence-interval-focused approach and simulations, I show how to conduct power analyses for minimum-effect and equivalence testing. Moreover, I show that conducting a power analysis for the SESOI might result in inconclusive results. This confidence-interval-focused simulation-based power analysis can be easily adopted to different types of research areas and designs. Last, I provide recommendations on how to conduct such simulation-based power analyses.   

Capturing the Social Life of a Person by Integrating Experience-Sampling Methodology and Personal-Social-Network Assessments Marie Stadel, Laura F. Bringmann, Gert Stulp, et al.

The daily social life of a person can be captured with different methodologies. Two methods that are especially promising are personal-social-network (PSN) data collection and experience-sampling methodology (ESM). Whereas PSN data collections ask participants to provide information on their social relationships and broader social environment, ESM studies collect intensive longitudinal data on social interactions in daily life using multiple short surveys per day. In combination, the two methods enable detailed insights into someone’s social life, including information on interactions with specific interaction partners from the personal network. Despite many potential uses of such data integration, there are few studies to date using the two methods in conjunction. This is likely due to their complexity and lack of software that allows capturing the full social life of someone while keeping the burden for participants and researchers sufficiently low. In this article, we report on the development of methodology and software for an ESM/PSN integration within the established ESM tool m-Path. We describe results of a first study using the developed tool that illustrate the feasibility of the proposed method combination and show that participants consider the assessments insightful. We further outline study-design choices and ethical considerations when combining the two methodologies. We hope to encourage applications of the presented methods in research and practice across different fields.   

The Incremental Propensity Score Approach for Diversity Science Wen Wei Loh, Dongning Ren    

Addressing core questions in diversity science requires quantifying causal effects (e.g., what drives social inequities and how to reduce them). Conventional approaches target the average causal effect (ACE), but ACE-based analyses suffer from limitations that undermine their relevance for diversity science. In this article, we introduce a novel alternative from the causal inference literature: the so-called incremental propensity score (IPS). First, we explain why the IPS is well suited for investigating core queries in diversity science. Unlike the ACE, the IPS does not demand conceptualizing unrealistic counterfactual scenarios in which everyone in the population is uniformly exposed versus unexposed to a causal factor. Instead, the IPS focuses on the effect of hypothetically shifting individuals’ chances of being exposed along a continuum. This allows seeing how the effect may be graded, offering a more realistic and policy-relevant quantification of the causal effect than a single ACE estimate. Moreover, the IPS does not require the positivity assumption, a necessary condition for estimating the ACE but which rarely holds in practice. Next, to broaden accessibility, we provide a step-by-step guide on estimating the IPS using R, a free and popular software. Finally, we illustrate the IPS using two real-world examples. The current article contributes to the methodological advancement in diversity science and offers researchers a more realistic, relevant, and meaningful approach.   

Practices in Data-Quality Evaluation: A Large-Scale Review of Online Survey Studies Published in 2022 Jaroslav Gottfried    

In this study, I examine data-quality evaluation methods in online surveys and their frequency of use. Drawing from survey-methodology literature, I identified 11 distinct assessment categories and analyzed their prevalence across 3,298 articles published in 2022 from 200 psychology journals in the Web of Science Master Journal List. These English-language articles employed original data from self-administered online questionnaires. Strikingly, 55% of articles opted not to employ any data-quality evaluation, and 24% employed only one method despite the wide repertoire of methods available. The most common data-quality indicators were attention-control items (22%) and nonresponse rates (13%). Strict and unjustified nonresponse-based data-exclusion criteria were often observed. The results highlight a trend of inadequate quality control in online survey research, leaving results vulnerable to biases from automated response bots or respondents’ carelessness and fatigue. More thorough data-quality assurance is currently needed for online surveys.   

Implementing Statcheck During Peer Review Is Related to a Steep Decline in Statistical-Reporting Inconsistencies Michèle B. Nuijten, Jelte M. Wicherts   

We investigated whether statistical-reporting inconsistencies could be avoided if journals implement the tool statcheck in the peer-review process. In a preregistered pretest–posttest quasi-experiment covering more than 7,000 articles and more than 147,000 extracted statistics, we compared the prevalence of reported p values that were inconsistent with their degrees of freedom and test statistics in two journals that implemented statcheck in their peer-review process ( Psychological Science and Journal of Experimental and Social Psychology ) and two matched control journals ( Journal of Experimental Psychology: General and Journal of Personality and Social Psychology ) before and after statcheck was implemented. Preregistered multilevel logistic regression analyses showed that the decrease in both inconsistencies and decision inconsistencies around p = .05 is considerably steeper in statcheck journals than in control journals, offering preliminary support for the notion that statcheck can be a useful tool for journals to avoid statistical-reporting inconsistencies in published articles. We discuss limitations and implications of these findings.   

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Scientists Propose Upgrades to Research-Methods Education for Psychology Students 

Many undergraduate psychology courses fail to ensure students fully understand research design and analysis. An international team of psychological scientists have recommended some systemic steps to remedy that shortcoming.

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Multilab Replication Challenges Long-held Theories on Cognitive Dissonance

One of the foremost models that scientists use to measure the effects of cognitive dissonance may have some deficiencies, a new multilab registered replication indicates.

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When Things Don’t Go According to Plan

Methodologists have embraced preregistration as a way to prevent questionable research practices and add transparency to scientific studies. But many researchers end up deviating from those preregistered plans, and those deviations aren’t reported systematically, if at all.

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  • 21 August 2024

South Korean science on the global stage

Research output.

South Korea's Share in natural-science journals in the Nature Index is shown alongside its closest competitors in the database. Among these countries, India is the only one to have increased its natural-science output between 2019 and 2023, with a 14.5% jump in adjusted Share between 2022 and 2023 alone.

People power

South Korea has the most researchers in science, technology and innovation roles (full-time equivalent) per million inhabitants — and by a large margin. It is notably the only non-European country in the top 10 by this measure in 2021. Japan, not shown here, is ranked 11th.

Subject strengths

A breakdown of subject contributions to countries’ overall 2023 output in journals tracked by the Nature Index is shown for South Korea and some of its closest competitors. With almost 55% of its output attributed to the physical sciences, South Korea joins India in this group as having a dominant subject that is worth more than half of its total output. France and Switzerland, by comparison, have a more balanced output.

The fastest rising South Korean institutions for the period 2019 to 2023 have recorded very modest gains in natural-science output in the Index, which could speak to the country’s relatively stable performance in recent years. Samsung Group, the only corporate institution in this list, had the largest percentage increase over the period, at 57.98%. This was from a much smaller adjusted Share of 10.77 in 2019, however, compared with Seoul National University at 174.97.

Most improved

The fastest-rising institutions in four natural-science subjects, and in the natural sciences overall, are shown for the period 2019 to 2023. Institutions are ranked according to change in adjusted Share, which for the Pohang University of Science and Technology was larger in the physical sciences than it was in the natural sciences overall.

A bar graph showing the fastest-rising institutions in four natural-science subjects, and in the natural sciences overall, in the Nature Index for the period 2019 to 2023.

Source: Nature Index

Big spender

Although South Korea spends more on its research and development as a proportion of its gross domestic product than most other countries in the world, this does not translate to higher Share in the Nature Index. Its output does seem relatively stable, however; among the selected countries shown below, many recorded a decline in Share (per million people) in natural-science journals over the past five years, but South Korea’s drop was smaller than most.

Nature 632 , S8-S9 (2024)

doi: https://doi.org/10.1038/d41586-024-02686-x

This article is part of Nature Index 2024 South Korea , an editorially independent supplement. Advertisers have no influence over the content. For more information about Nature Index, see the homepage .

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What will it take to open South Korean research to the world?

What will it take to open South Korean research to the world?

How South Korea can build better gender diversity into research

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The University of Texas at San Antonio and The University of Texas Health Science Center at San Antonio will merge into one premier global university to best serve the growing needs of the region and state, combining their collective academic, research, and clinical strengths to deliver immense value to the communities they serve.

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UTSA and UT Health San Antonio will unite their strengths to create a global powerhouse in education, healthcare, and innovation that exceeds the sum of its parts.

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The most impactful and prestigious public research universities in the country combine top-tier academic and health science components within a single institution. This new university will leverage its size and scale to bring significant advantages to Texas on a national level. Great cities thrive with great universities, and great universities, in turn, make cities even greater.

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San Antonio, the second-largest city in Texas and seventh largest in the U.S., serves as the gateway to South Texas, home to 5.5 million people and projected to grow to 6.1 million by 2040. It plays a crucial role in Texas’ care for its citizens and in maintaining the state's national competitiveness.

This unified institution will activate and accelerate the complementary strengths of UTSA and UTHSA, expanding academic degree programs, bolstering the healthcare enterprise, multiplying research, technological, and commercialization advancements, and empowering the next generation of innovators, educators, and healthcare providers to build a highly skilled workforce that benefits society.  

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A Guide to Writing a Scientific Paper: A Focus on High School Through Graduate Level Student Research

Renee a. hesselbach.

1 NIEHS Children's Environmental Health Sciences Core Center, University of Wisconsin—Milwaukee, Milwaukee, Wisconsin.

David H. Petering

2 Department of Chemistry and Biochemistry, University of Wisconsin—Milwaukee, Milwaukee, Wisconsin.

Craig A. Berg

3 Curriculum and Instruction, University of Wisconsin—Milwaukee, Milwaukee, Wisconsin.

Henry Tomasiewicz

Daniel weber.

This article presents a detailed guide for high school through graduate level instructors that leads students to write effective and well-organized scientific papers. Interesting research emerges from the ability to ask questions, define problems, design experiments, analyze and interpret data, and make critical connections. This process is incomplete, unless new results are communicated to others because science fundamentally requires peer review and criticism to validate or discard proposed new knowledge. Thus, a concise and clearly written research paper is a critical step in the scientific process and is important for young researchers as they are mastering how to express scientific concepts and understanding. Moreover, learning to write a research paper provides a tool to improve science literacy as indicated in the National Research Council's National Science Education Standards (1996), and A Framework for K–12 Science Education (2011), the underlying foundation for the Next Generation Science Standards currently being developed. Background information explains the importance of peer review and communicating results, along with details of each critical component, the Abstract, Introduction, Methods, Results , and Discussion . Specific steps essential to helping students write clear and coherent research papers that follow a logical format, use effective communication, and develop scientific inquiry are described.

Introduction

A key part of the scientific process is communication of original results to others so that one's discoveries are passed along to the scientific community and the public for awareness and scrutiny. 1 – 3 Communication to other scientists ensures that new findings become part of a growing body of publicly available knowledge that informs how we understand the world around us. 2 It is also what fuels further research as other scientists incorporate novel findings into their thinking and experiments.

Depending upon the researcher's position, intent, and needs, communication can take different forms. The gold standard is writing scientific papers that describe original research in such a way that other scientists will be able to repeat it or to use it as a basis for their studies. 1 For some, it is expected that such articles will be published in scientific journals after they have been peer reviewed and accepted for publication. Scientists must submit their articles for examination by other scientists familiar with the area of research, who decide whether the work was conducted properly and whether the results add to the knowledge base and are conveyed well enough to merit publication. 2 If a manuscript passes the scrutiny of peer-review, it has the potential to be published. 1 For others, such as for high school or undergraduate students, publishing a research paper may not be the ultimate goal. However, regardless of whether an article is to be submitted for publication, peer review is an important step in this process. For student researchers, writing a well-organized research paper is a key step in learning how to express understanding, make critical connections, summarize data, and effectively communicate results, which are important goals for improving science literacy of the National Research Council's National Science Education Standards, 4 and A Framework for K–12 Science Education, 5 and the Next Generation Science Standards 6 currently being developed and described in The NSTA Reader's Guide to A Framework for K–12 Science Education. 7 Table 1 depicts the key skills students should develop as part of the Science as Inquiry Content Standard. Table 2 illustrates the central goals of A Framework for K–12 Science Education Scientific and Engineering Practices Dimension.

Key Skills of the Science as Inquiry National Science Education Content Standard

Identify questions and concepts that guide scientific investigation
Design and conduct scientific investigations
Use technology and mathematics to improve investigations and communications
Formulate and revise scientific explanations and models using logic and evidence
Recognize and analyze alternative explanations and models
Communicate and defend a scientific argument

National Research Council (1996).

Important Practices of A Framework for K–12 Science Education Scientific and Engineering Practices Dimension

Asking questions and defining problems
Developing and using models
Planning and carrying out investigations
Analyzing and interpreting data
Using mathematics and computational thinking
Constructing explanations and designing solutions
Engaging in argument from evidence
Obtaining, evaluating, and communicating information

National Research Council (2011).

Scientific papers based on experimentation typically include five predominant sections: Abstract, Introduction, Methods, Results, and Discussion . This structure is a widely accepted approach to writing a research paper, and has specific sections that parallel the scientific method. Following this structure allows the scientist to tell a clear, coherent story in a logical format, essential to effective communication. 1 , 2 In addition, using a standardized format allows the reader to find specific information quickly and easily. While readers may not have time to read the entire research paper, the predictable format allows them to focus on specific sections such as the Abstract , Introduction , and Discussion sections. Therefore, it is critical that information be placed in the appropriate and logical section of the report. 3

Guidelines for Writing a Primary Research Article

The Title sends an important message to the reader about the purpose of the paper. For example, Ethanol Effects on the Developing Zebrafish: Neurobehavior and Skeletal Morphogenesis 8 tells the reader key information about the content of the research paper. Also, an appropriate and descriptive title captures the attention of the reader. When composing the Title , students should include either the aim or conclusion of the research, the subject, and possibly the independent or dependent variables. Often, the title is created after the body of the article has been written, so that it accurately reflects the purpose and content of the article. 1 , 3

The Abstract provides a short, concise summary of the research described in the body of the article and should be able to stand alone. It provides readers with a quick overview that helps them decide whether the article may be interesting to read. Included in the Abstract are the purpose or primary objectives of the experiment and why they are important, a brief description of the methods and approach used, key findings and the significance of the results, and how this work is different from the work of others. It is important to note that the Abstract briefly explains the implications of the findings, but does not evaluate the conclusions. 1 , 3 Just as with the Title , this section needs to be written carefully and succinctly. Often this section is written last to ensure it accurately reflects the content of the paper. Generally, the optimal length of the Abstract is one paragraph between 200 and 300 words, and does not contain references or abbreviations.

All new research can be categorized by field (e.g., biology, chemistry, physics, geology) and by area within the field (e.g., biology: evolution, ecology, cell biology, anatomy, environmental health). Many areas already contain a large volume of published research. The role of the Introduction is to place the new research within the context of previous studies in the particular field and area, thereby introducing the audience to the research and motivating the audience to continue reading. 1

Usually, the writer begins by describing what is known in the area that directly relates to the subject of the article's research. Clearly, this must be done judiciously; usually there is not room to describe every bit of information that is known. Each statement needs one or more references from the scientific literature that supports its validity. Students must be reminded to cite all references to eliminate the risk of plagiarism. 2 Out of this context, the author then explains what is not known and, therefore, what the article's research seeks to find out. In doing so, the scientist provides the rationale for the research and further develops why this research is important. The final statement in the Introduction should be a clearly worded hypothesis or thesis statement, as well as a brief summary of the findings as they relate to the stated hypothesis. Keep in mind that the details of the experimental findings are presented in the Results section and are aimed at filling the void in our knowledge base that has been pointed out in the Introduction .

Materials and Methods

Research utilizes various accepted methods to obtain the results that are to be shared with others in the scientific community. The quality of the results, therefore, depends completely upon the quality of the methods that are employed and the care with which they are applied. The reader will refer to the Methods section: (a) to become confident that the experiments have been properly done, (b) as the guide for repeating the experiments, and (c) to learn how to do new methods.

It is particularly important to keep in mind item (b). Since science deals with the objective properties of the physical and biological world, it is a basic axiom that these properties are independent of the scientist who reported them. Everyone should be able to measure or observe the same properties within error, if they do the same experiment using the same materials and procedures. In science, one does the same experiment by exactly repeating the experiment that has been described in the Methods section. Therefore, someone can only repeat an experiment accurately if all the relevant details of the experimental methods are clearly described. 1 , 3

The following information is important to include under illustrative headings, and is generally presented in narrative form. A detailed list of all the materials used in the experiments and, if important, their source should be described. These include biological agents (e.g., zebrafish, brine shrimp), chemicals and their concentrations (e.g., 0.20 mg/mL nicotine), and physical equipment (e.g., four 10-gallon aquariums, one light timer, one 10-well falcon dish). The reader needs to know as much as necessary about each of the materials; however, it is important not to include extraneous information. For example, consider an experiment involving zebrafish. The type and characteristics of the zebrafish used must be clearly described so another scientist could accurately replicate the experiment, such as 4–6-month-old male and female zebrafish, the type of zebrafish used (e.g., Golden), and where they were obtained (e.g., the NIEHS Children's Environmental Health Sciences Core Center in the WATER Institute of the University of Wisconsin—Milwaukee). In addition to describing the physical set-up of the experiment, it may be helpful to include photographs or diagrams in the report to further illustrate the experimental design.

A thorough description of each procedure done in the reported experiment, and justification as to why a particular method was chosen to most effectively answer the research question should also be included. For example, if the scientist was using zebrafish to study developmental effects of nicotine, the reader needs to know details about how and when the zebrafish were exposed to the nicotine (e.g., maternal exposure, embryo injection of nicotine, exposure of developing embryo to nicotine in the water for a particular length of time during development), duration of the exposure (e.g., a certain concentration for 10 minutes at the two-cell stage, then the embryos were washed), how many were exposed, and why that method was chosen. The reader would also need to know the concentrations to which the zebrafish were exposed, how the scientist observed the effects of the chemical exposure (e.g., microscopic changes in structure, changes in swimming behavior), relevant safety and toxicity concerns, how outcomes were measured, and how the scientist determined whether the data/results were significantly different in experimental and unexposed control animals (statistical methods).

Students must take great care and effort to write a good Methods section because it is an essential component of the effective communication of scientific findings.

The Results section describes in detail the actual experiments that were undertaken in a clear and well-organized narrative. The information found in the Methods section serves as background for understanding these descriptions and does not need to be repeated. For each different experiment, the author may wish to provide a subtitle and, in addition, one or more introductory sentences that explains the reason for doing the experiment. In a sense, this information is an extension of the Introduction in that it makes the argument to the reader why it is important to do the experiment. The Introduction is more general; this text is more specific.

Once the reader understands the focus of the experiment, the writer should restate the hypothesis to be tested or the information sought in the experiment. For example, “Atrazine is routinely used as a crop pesticide. It is important to understand whether it affects organisms that are normally found in soil. We decided to use worms as a test organism because they are important members of the soil community. Because atrazine damages nerve cells, we hypothesized that exposure to atrazine will inhibit the ability of worms to do locomotor activities. In the first experiment, we tested the effect of the chemical on burrowing action.”

Then, the experiments to be done are described and the results entered. In reporting on experimental design, it is important to identify the dependent and independent variables clearly, as well as the controls. The results must be shown in a way that can be reproduced by the reader, but do not include more details than needed for an effective analysis. Generally, meaningful and significant data are gathered together into tables and figures that summarize relevant information, and appropriate statistical analyses are completed based on the data gathered. Besides presenting each of these data sources, the author also provides a written narrative of the contents of the figures and tables, as well as an analysis of the statistical significance. In the narrative, the writer also connects the results to the aims of the experiment as described above. Did the results support the initial hypothesis? Do they provide the information that was sought? Were there problems in the experiment that compromised the results? Be careful not to include an interpretation of the results; that is reserved for the Discussion section.

The writer then moves on to the next experiment. Again, the first paragraph is developed as above, except this experiment is seen in the context of the first experiment. In other words, a story is being developed. So, one commonly refers to the results of the first experiment as part of the basis for undertaking the second experiment. “In the first experiment we observed that atrazine altered burrowing activity. In order to understand how that might occur, we decided to study its impact on the basic biology of locomotion. Our hypothesis was that atrazine affected neuromuscular junctions. So, we did the following experiment..”

The Results section includes a focused critical analysis of each experiment undertaken. A hallmark of the scientist is a deep skepticism about results and conclusions. “Convince me! And then convince me again with even better experiments.” That is the constant challenge. Without this basic attitude of doubt and willingness to criticize one's own work, scientists do not get to the level of concern about experimental methods and results that is needed to ensure that the best experiments are being done and the most reproducible results are being acquired. Thus, it is important for students to state any limitations or weaknesses in their research approach and explain assumptions made upfront in this section so the validity of the research can be assessed.

The Discussion section is the where the author takes an overall view of the work presented in the article. First, the main results from the various experiments are gathered in one place to highlight the significant results so the reader can see how they fit together and successfully test the original hypotheses of the experiment. Logical connections and trends in the data are presented, as are discussions of error and other possible explanations for the findings, including an analysis of whether the experimental design was adequate. Remember, results should not be restated in the Discussion section, except insofar as it is absolutely necessary to make a point.

Second, the task is to help the reader link the present work with the larger body of knowledge that was portrayed in the Introduction . How do the results advance the field, and what are the implications? What does the research results mean? What is the relevance? 1 , 3

Lastly, the author may suggest further work that needs to be done based on the new knowledge gained from the research.

Supporting Documentation and Writing Skills

Tables and figures are included to support the content of the research paper. These provide the reader with a graphic display of information presented. Tables and figures must have illustrative and descriptive titles, legends, interval markers, and axis labels, as appropriate; should be numbered in the order that they appear in the report; and include explanations of any unusual abbreviations.

The final section of the scientific article is the Reference section. When citing sources, it is important to follow an accepted standardized format, such as CSE (Council of Science Editors), APA (American Psychological Association), MLA (Modern Language Association), or CMS (Chicago Manual of Style). References should be listed in alphabetical order and original authors cited. All sources cited in the text must be included in the Reference section. 1

When writing a scientific paper, the importance of writing concisely and accurately to clearly communicate the message should be emphasized to students. 1 – 3 Students should avoid slang and repetition, as well as abbreviations that may not be well known. 1 If an abbreviation must be used, identify the word with the abbreviation in parentheses the first time the term is used. Using appropriate and correct grammar and spelling throughout are essential elements of a well-written report. 1 , 3 Finally, when the article has been organized and formatted properly, students are encouraged to peer review to obtain constructive criticism and then to revise the manuscript appropriately. Good scientific writing, like any kind of writing, is a process that requires careful editing and revision. 1

A key dimension of NRC's A Framework for K–12 Science Education , Scientific and Engineering Practices, and the developing Next Generation Science Standards emphasizes the importance of students being able to ask questions, define problems, design experiments, analyze and interpret data, draw conclusions, and communicate results. 5 , 6 In the Science Education Partnership Award (SEPA) program at the University of Wisconsin—Milwaukee, we found the guidelines presented in this article useful for high school science students because this group of students (and probably most undergraduates) often lack in understanding of, and skills to develop and write, the various components of an effective scientific paper. Students routinely need to focus more on the data collected and analyze what the results indicated in relation to the research question/hypothesis, as well as develop a detailed discussion of what they learned. Consequently, teaching students how to effectively organize and write a research report is a critical component when engaging students in scientific inquiry.

Acknowledgments

This article was supported by a Science Education Partnership Award (SEPA) grant (Award Number R25RR026299) from the National Institute of Environmental Health Sciences of the National Institutes of Health. The SEPA program at the University of Wisconsin—Milwaukee is part of the Children's Environmental Health Sciences Core Center, Community Outreach and Education Core, funded by the National Institute of Environmental Health Sciences (Award Number P30ES004184). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the National Institute of Environmental Health Sciences.

Disclosure Statement

No competing financial interests exist.

IMAGES

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COMMENTS

  1. PDF How to Write Paper in Scientific Journal Style and Format

    Lewiston, ME. v. 10‐2014. This is a reference sheet to help you remember the common format we expect you to use on your formal lab write‐ups. Refer to the "How to Write Guide" for the details. Other than the title, use 12 point type, preferably Calibri, Times New Roman, or Courier.

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  3. Successful Scientific Writing and Publishing: A Step-by-Step Approach

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  4. Instructions for preparing an initial manuscript

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    Then, writing the paper and getting it ready for submission may take me 3 to 6 months. I like separating the writing into three phases. The results and the methods go first, as this is where I write what was done and how, and what the outcomes were. In a second phase, I tackle the introduction and refine the results section with input from my ...

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  19. Word templates for journal articles

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