example research proposal on breast cancer

prevalent cases of cancer and about 35,000 new cases are added to this every year. Based on the. (18.5%) it ranks second to cervical cancer. The burden of breast cancer is increasing in both. rate ...

r loss of PTEN in breast cancer. We propo. e to address the following Aims:Aim1: Deconstruct the metabolic phenome conferred by the activation of PI3K. Akt signalli. g in breast cancer.Objective 1. Characterisation of cellular metabolism conferred by oncogenic mutations in PI. 3CA and/or l.

Research Proposal PDF Available. ... Breast cancer is the most common diagnosed malignancy in women worldwide (22%) and in India (18.5%) it ranks second to cervical cancer. ... for example, to.

new case diagnosed every 18 seconds; additionally, 626,679 women with breast cancer died. The global. incidence of breast cancer has been rising wi th annual. increases of 3.1%, beginning with ...

id/955951), tackling different aspects of the metastatic process. In addition to undertaking a dedicated research project at the ICR, the student will participate. in EVOMET meetings, workshops and two 2-month secondments abroad. This project will focus on invasive lobular breast cancer (ILC). ILC is the 2nd most common form of breast c.

Sample Research Proposal for the Department of Psychology Chair's Minority/Underrepresented Research Grant The Roles of Body Image and Self-Esteem in Breast Cancer Treatment Decisions Project Overview Breast cancer is the second most commonly diagnosed cancer among women, and has the second

a. Targeting cancer metabolism to combat bone metastasis of breast cancer b. Elucidating the role of dietary interventions in therapy response RESEARCH PROPOSAL In the context of this Proposal, and building on our preliminary results, two main aims will be pursued: 1.

The purpose of this mixed-method study was to investigate levels of PTSD, PTG, QOL, their relationships, and unmet mental health needs of triple-negative breast cancer survivors diagnosed between stages 2b-4 and 2-5 years post-treatment. Participants were recruited through two cancer organizations, breast health navigators, TNBC support groups, and online breast cancer support groups.

New research questions emerge as medical needs continue to evolve and as we improve our understanding of cancer biology and treatment of malignancies. Although significant advances have been made in some areas of breast cancer research resulting in improvements in therapies and outcomes over the last few decades, other areas have not benefited to the same degree and we continue to have many ...

Black cancer patients in the United States have both increased overall cancer mortality and increased cancer-specific mortality 1,2,3. In breast cancer, Black women have a 41% higher risk of dying ...

Current Funding Opportunities. Through our research program, Komen awards grants to support cutting-edge breast cancer research that will provide the greatest benefit to patients. We're focused on conquering metastatic and aggressive breast cancers, advancing personalized breast care and eliminating breast cancer disparities and inequities.

Introduction Breast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translating solutions into practice. Methods More than 100 internationally recognised specialist breast cancer scientists, clinicians and healthcare ...

In recent years, the reported number of new breast cancer cases reached approximately 2.3 million worldwide, contributing to an estimated 685,000 deaths attributed to this disease 1.So, despite ...

Figure 1. Example classifications of a malignant tumor (right) and benign tumor (left) from our model. Green is for ground truth, Red is for a malignant tumor classification, and blue is for a benign tumor [15] 2.3. Deep Learning For Breast Cancer Detection: Regions of Interest Many of the relevant difficulties in breast cancer detec-

INTRODUCTION The Sharing Progress in Cancer Care (SPCC) and Pfizer Global Medical Grants (Pfizer) are collaborating to offer a new grant opportunity seeking proposals in support of improving care of metastatic breast cancer (MBC) patients in Europe. The intent of this RFP is to encourage the submission of proposals describing concepts and ideas to improve the quality

NCI is funding a large-scale randomized breast screening trial, the Tomosynthesis Mammographic Imaging Screening Trial (TMIST), to compare the number of advanced cancers detected in women screened for 5 years with 3-D mammography with the number detected in women screened with 2-D mammography. Two concerns in breast cancer screening, as in all ...

According to the International Agency for Research on Cancer of the World Health Organization in 2021, the incidence of breast cancer has surpassed that of lung cancer, becoming the most common cancer worldwide [].The pathogenesis of breast cancer is complex, with numerous identified risk factors, including genetic mutations (BRCA1, BRCA2) [], lifestyle factors (alcohol consumption, smoking ...

Deciding which research topics to focus on in medicine and health depends on many factors. These factors can include the currency of a topic, feedback from people providing or receiving care, and the priorities of funders. In late 2019, the Cochrane Breast Cancer Group (part of Cochrane's Cancer Network) conducted a formal priority-setting ...

Breast conserving treatment typically involves surgical excision of tumor and adjuvant radiotherapy targeting the breast area or tumor bed. Accurately defining the tumor bed is challenging and lead to irradiation of greater volume of healthy tissues. Preoperative stereotactic body radiotherapy (SBRT) which target tumor may solves that issues. We conducted a systematic literature review to ...

The 2011 Early Breast Cancer Trialists' Collaborative Group meta-analysis of more than 10 000 women treated with breast-conserving surgery with or without postoperative whole-breast radiotherapy showed that radiotherapy halved the risk of first recurrence (most of which were local) at 10 years, and this translated into a modest reduction in ...

In April 2024, the US Preventive Services Task Force (USPSTF) recommended that women aged 40 to 74 years with an average risk of breast cancer undergo mammography screening every 2 years. This updated the USPSTF's prior suggestion that women aged 40 to 49 years engage in shared decision-making with their clinician before deciding whether to be screened.

Posted: January 20, 2023. Many young women who are diagnosed with early-stage breast cancer want to become pregnant in the future. New research suggests that these women may be able to pause their hormone therapy for up to 2 years as they try to get pregnant without raising the risk of a recurrence in the short term.

The result of the study indicated that; Secondary school female teachers in Rivers State have average knowledge level (60.6%) of breast cancer. 47.9% have poor knowledge of breast cancer risk ...

Title of Project. Grant Mechanism & Award Number. Elizabeth Kantor, PhD, MPH, Memorial Sloan Kettering Cancer Center. Obesity, Chemotherapy Dosing, and Breast Cancer Outcomes. View Abstract. R37 CA222793-04. View Grant Application. [PDF - 1.48 MB] Anna Prizment, PhD, University of Minnesota.

Ongoing research and treatment advances are providing hope and improving outcomes in patients with metastatic breast cancer. Dr. Wade Smith, a medical oncologist specializing in breast cancer at City of Hope in California, discussed the role of research, personalized care and new treatment options for patients during a session of CURE® Educated Patient® Updates in Metastatic Breast Cancer.

Sample Grant Applications. Several investigators and their organizations agreed to post part of their dissemination and implementation grant applications online. We are grateful to them for letting us provide this resource to the community. Note: These sample grants predate some recent grants policy changes, including NIH's Data Management ...

Calls for Proposals will be issued by Against Breast Cancer (ABC) and researchers are invited to apply before the advertised deadline date using the template forms provided. Against Breast Cancer Seed Grants are intended for innovative research projects that have the potential to impact the way metastatic breast cancer is diagnosed, treated or ...

Abstract. Current proposals for a monitoring and evaluation system in breast cancer screening programmes focus on mortality reduction. Here emphasis is laid on the prevention of too high a number of false-positive screening results, i.e. no subsequent demonstration of malignancy. By comparing the specificity of the screening test, the positive ...

1. Show clearly how the application builds on existing knowledge. Your research must be based on solid principles. 2. Spend time on the abstract. Include all aspects of the study so the reviewers can immediately see everything you plan to do. Make sure it's clear, concise, and thorough. 3.

We are committed to supporting young investigators in breast cancer research and encourage applications from talented new postdoctoral researchers. 2. Eligibility ... research proposal for a different award (for example, a rejected fellowship resubmitted as a project grant), you must include a covering letter acknowledging the rejected grant ...